PANTHER Gene Information

Gene Symbol(s):

Krt18

Organism:

Rattus norvegicus

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Gene Name:

Keratin, type I cytoskeletal 18

Gene ID:

619935

Protein ID:

Q5BJY9

Persistent Id:

PTN000580169

Alternate Ids:

73621121(GI)	K18(Synonym)
294853(GeneID)	NM_053976(refSeq)
619935(RGD)	ENSRNOP00000067234(Ensembl_PRO)
Krt18{ECO:0000250\|UniProtKB:P05783}(Symbol)	Q63278(AltAccession)
BC091275(EMBL)	ENSRNOT00000073951(Ensembl_TRS)
ENSRNOG00000047393(Ensembl)	CAA57204(EMBL-CDS)
K1C18_RAT(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	INTERMEDIATE FILAMENT (PTHR23239)
PANTHER Subfamily:	KERATIN, TYPE I CYTOSKELETAL 18 (PTHR23239:SF349)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	intermediate filament cytoskeleton organization
PANTHER GO-slim Cellular Component:	keratin filament
PANTHER protein class:	intermediate filament

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	scaffold protein binding, structural molecule activity
GO BP Complete:	tumor necrosis factor-mediated signaling pathway, response to fructose, hepatocyte differentiation, negative regulation of apoptotic process, mesenchymal stem cell differentiation, intermediate filament cytoskeleton organization, extrinsic apoptotic signaling pathway, Golgi to plasma membrane protein transport, cholangiocyte apoptotic process, response to nutrient levels, hepatocyte apoptotic process
GO CC Complete:	centriolar satellite, external side of plasma membrane, intermediate filament, nucleolus, extracellular space, cytoskeleton, keratin filament, perinuclear region of cytoplasm, microtubule organizing center, cytoplasm, cytosol, nuclear matrix, protein-containing complex, cell periphery

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Formation of the cornified envelope, Developmental Biology, Keratinization

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000051489.1\|UniProtKB=A0A2I3SM20	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000021954.2\|UniProtKB=A0A2I2YBX7	Gorilla gorilla gorilla	O
PANTR\|Ensembl=ENSPTRG00000044139.1\|UniProtKB=A0A2I3RRI5	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000024203.2\|UniProtKB=G3S9X8	Gorilla gorilla gorilla	O
HUMAN\|HGNC=6430\|UniProtKB=P05783	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000047333.1\|UniProtKB=A0A2I3RAY7	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000004996.4\|UniProtKB=H2Q609	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000025508.2\|UniProtKB=G3SE94	Gorilla gorilla gorilla	O
GORGO\|Ensembl=ENSGGOG00000024155.2\|UniProtKB=A0A2I2ZWP5	Gorilla gorilla gorilla	O
GORGO\|Ensembl=ENSGGOG00000010157.3\|UniProtKB=G3R3T2	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000043308.2\|UniProtKB=A0A5F7ZHW8	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000031911.3\|UniProtKB=F6VBK4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=96692\|UniProtKB=P05784	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000001517.6\|UniProtKB=F6S1Q0	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000000253.5\|UniProtKB=A0A5G2RBD3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000038379.3\|UniProtKB=A0A9L0QY80	Equus caballus	LDO
HORSE\|Ensembl=ENSECAG00000002256.4\|UniProtKB=F6VY00	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000000299.6\|UniProtKB=M3VUH3	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845023645.1\|UniProtKB=A0A8I3PJ84	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000036454.1\|UniProtKB=A0A5F8GUW7	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000045852.1\|UniProtKB=A0A6I8PG64	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010024018.1\|UniProtKB=A0A8V1A2T7	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000011762.4\|UniProtKB=H9GI59	Anolis carolinensis	LDO
XENLA\|Gene=krt18-a\|UniProtKB=P08802	Xenopus laevis	O
XENLA\|Gene=krt18-b\|UniProtKB=Q7SY65	Xenopus laevis	LDO
ORYLA\|Ensembl=ENSORLG00000016545.2\|UniProtKB=H2MPQ2	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-040426-1508\|UniProtKB=Q6PHE4	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000001491.2\|UniProtKB=H2L7M8	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000001481.2\|UniProtKB=H2L7M4	Oryzias latipes	LDO
DANRE\|Gene=si=ch211-133j6.3\|UniProtKB=A0A8N7TEZ1	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-030411-6\|UniProtKB=Q7ZTS4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000005463.1\|UniProtKB=W5MDY8	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118405578\|UniProtKB=A0A9J7HMI6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118403465\|UniProtKB=A0A9J7KGN5	Branchiostoma floridae	O