PANTHER Gene Information

Gene Symbol(s):

Defa38

Organism:

Mus musculus

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Gene Name:

CRS1C-2

Gene ID:

MGI:3709605

Protein ID:

Q5ERJ0

Persistent Id:

PTN000933786

Alternate Ids:

Q5ERJ0(Synonym)	ENSMUSP00000076665(Ensembl_PRO)
634825(GeneID)	MGI:3709605(MGI)
Q5ERJ0_MOUSE(UniProtKB-ID)	ENSMUST00000077452(Ensembl_TRS)
58891607(GI)	NP_001170953(refSeq)
AAW83122(EMBL-CDS)	ENSMUSG00000061958(Ensembl)
AY761183(EMBL)
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PANTHER Classification

PANTHER Family:	ALPHA-DEFENSIN 1 (PTHR11876)
PANTHER Subfamily:	ALPHA-DEFENSIN 1-RELATED (PTHR11876:SF2)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	defense response to Gram-positive bacterium antimicrobial humoral immune response mediated by antimicrobial peptide antibacterial humoral response cellular response to lipopolysaccharide defense response to Gram-negative bacterium innate immune response
PANTHER GO-slim Cellular Component:	extracellular space extracellular matrix
PANTHER protein class:	antimicrobial response protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	protein homodimerization activity, molecular_function
GO BP Complete:	disruption of plasma membrane integrity in another organism, innate immune response in mucosa, defense response to Gram-negative bacterium, cellular response to lipopolysaccharide, antibacterial humoral response, defense response to Gram-positive bacterium, antimicrobial humoral immune response mediated by antimicrobial peptide
GO CC Complete:	extracellular space, azurophil granule

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Immune System, Alpha-defensins, Innate Immune System, Neutrophil degranulation, Antimicrobial peptides, Defensins

Orthologs

ID	Organism	Type
GORGO\|Ensembl=ENSGGOG00000039811.1\|UniProtKB=A0A2I2YQC3	Gorilla gorilla gorilla	O
MACMU\|Gene=RTD3_MACMU\|UniProtKB=Q9GLR2	Macaca mulatta	O
MACMU\|Gene=RTD1B\|UniProtKB=P82271	Macaca mulatta	O
MACMU\|Gene=RTD1A\|UniProtKB=P82270	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000049881.1\|UniProtKB=A0A5F8AES1	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000054742.1\|UniProtKB=A0A5F7Z7A6	Macaca mulatta	O
HUMAN\|HGNC=2763\|UniProtKB=P12838	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000034369\|UniProtKB=Q5G862	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000010900.3\|UniProtKB=G3R5N8	Gorilla gorilla gorilla	O
HUMAN\|HGNC=2765\|UniProtKB=Q01524	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000051516\|UniProtKB=Q5G860	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000010901.3\|UniProtKB=G3R5P2	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000052512.1\|UniProtKB=F7DMC6	Macaca mulatta	O
PANTR\|Gene=DEFA7\|UniProtKB=Q5G859	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000040805.1\|UniProtKB=A0A2I2Y9B9	Gorilla gorilla gorilla	O
HUMAN\|HGNC=2762\|UniProtKB=P59666	Homo sapiens	O
HUMAN\|HGNC=2761\|UniProtKB=P59665	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000050573\|UniProtKB=Q5G863	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000004514.3\|UniProtKB=G3QPD5	Gorilla gorilla gorilla	O
MACMU\|Gene=DEF8_MACMU\|UniProtKB=P60032	Macaca mulatta	O
MACMU\|Gene=DEF3_MACMU\|UniProtKB=P60031	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000018517\|UniProtKB=P60030	Macaca mulatta	O
HUMAN\|HGNC=2764\|UniProtKB=Q01523	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000049316\|UniProtKB=Q5G861	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000016102.3\|UniProtKB=G3RJ35	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000040721.2\|UniProtKB=A0A1D5QQV7	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000045717.2\|UniProtKB=F7DY92	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000054369.1\|UniProtKB=A0A5F7ZH18	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000054195.1\|UniProtKB=A0A5F8AQZ0	Macaca mulatta	O
MACMU\|Gene=DEF4_MACMU\|UniProtKB=P82319	Macaca mulatta	O
MACMU\|Gene=DEF6_MACMU\|UniProtKB=P82320	Macaca mulatta	O
RAT\|RGD=1304852\|UniProtKB=Q4JEI9	Rattus norvegicus	O
RAT\|RGD=1566065\|UniProtKB=Q4JEI6	Rattus norvegicus	O
RAT\|RGD=1562293\|UniProtKB=Q4JEI8	Rattus norvegicus	O
RAT\|Gene=DEF5_RAT\|UniProtKB=P82106	Rattus norvegicus	O
RAT\|RGD=1564555\|UniProtKB=Q4JEI5	Rattus norvegicus	O
RAT\|RGD=150344900\|UniProtKB=A0A8I6GLV0	Rattus norvegicus	O
RAT\|RGD=1561398\|UniProtKB=Q4JEI2	Rattus norvegicus	O
HORSE\|Ensembl=ENSECAG00000049963.1\|UniProtKB=C8BNH6	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000030501.2\|UniProtKB=C8BNG1	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000033357.1\|UniProtKB=C8BNI9	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000011787\|UniProtKB=A6YB85	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000027869.3\|UniProtKB=A0A3Q2HQJ5	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000039434.1\|UniProtKB=A0A3Q2GSZ3	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000032644.1\|UniProtKB=A0A3Q2IBF0	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000028505.2\|UniProtKB=A0A3Q2L6V2	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000043705.2\|UniProtKB=A0A5F5PG18	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000054883.1\|UniProtKB=C8BNG5	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000037168.3\|UniProtKB=A0A5F5PU65	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000051382.1\|UniProtKB=F6WLD2	Equus caballus	O
ORNAN\|Gene=DEFA2_ORNAN\|UniProtKB=P0C8A2	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000037525.1\|UniProtKB=A0A6I8PB05	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000050290\|UniProtKB=P0C8A3	Ornithorhynchus anatinus	O
TRIAD\|EnsemblGenome=TriadG55945\|UniProtKB=B3RTJ3	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG55948\|UniProtKB=B3RTJ6	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG55947\|UniProtKB=B3RTJ5	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG63910\|UniProtKB=B3RTJ8	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG63869\|UniProtKB=B3RVQ0	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG55946\|UniProtKB=B3RTJ4	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG55949\|UniProtKB=B3RTJ7	Trichoplax adhaerens	O