PANTHER Gene Information

Gene Symbol(s):

ABRAXAS1

Organism:

Rattus norvegicus

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Gene Name:

BRCA1-A complex subunit Abraxas 1

Gene ID:

1305287

Protein ID:

Q5I0F1

Persistent Id:

PTN000786826

Alternate Ids:

NM_001009633(refSeq)	81882976(GI)
BC088408(EMBL)	Ccdc98(Synonym)
1305287(RGD)	AAH88408(EMBL-CDS)
ABRX1_RAT(UniProtKB-ID)	289468(GeneID)
ABRAXAS1{ECO:0000312\|RGD:1305287}(Symbol)
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PANTHER Classification

PANTHER Family:	ABRAXAS FAMILY MEMBER (PTHR31728)
PANTHER Subfamily:	BRCA1-A COMPLEX SUBUNIT ABRAXAS 1 (PTHR31728:SF2)
PANTHER GO-slim Molecular Function:	microtubule binding polyubiquitin modification-dependent protein binding
PANTHER GO-slim Biological Process:	mitotic spindle assembly protein K63-linked deubiquitination attachment of spindle microtubules to kinetochore
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	polyubiquitin modification-dependent protein binding, microtubule binding
GO BP Complete:	positive regulation of DNA repair, DNA repair, mitotic G2 DNA damage checkpoint signaling, attachment of spindle microtubules to kinetochore, chromatin organization, double-strand break repair, response to ionizing radiation, protein K63-linked deubiquitination, mitotic spindle assembly
GO CC Complete:	nucleus, nuclear body, BRCA1-A complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

G2/M DNA damage checkpoint, Deubiquitination, DNA Repair, Metalloprotease DUBs, Cell Cycle, Cell Cycle Checkpoints, Metabolism of proteins, Nonhomologous End-Joining (NHEJ), Post-translational protein modification, G2/M Checkpoints, HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA), DNA Double-Strand Break Repair, Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks, Homology Directed Repair, DNA Double Strand Break Response, Processing of DNA double-strand break ends

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000049208.1\|UniProtKB=A0A2I3RA29	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000041876.1\|UniProtKB=A0A2I2YL74	Gorilla gorilla gorilla	O
HUMAN\|HGNC=25829\|UniProtKB=Q6UWZ7	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000023645.5\|UniProtKB=H2RA73	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000005818.3\|UniProtKB=G3QSQ4	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000030337.3\|UniProtKB=A0A1D5QK97	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1917931\|UniProtKB=Q8BPZ8	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000014076\|UniProtKB=Q5E9P1	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000009234.4\|UniProtKB=F1RW10	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000055802.1\|UniProtKB=A0A5F5Q135	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000018503.5\|UniProtKB=M3WPD0	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845021759.1\|UniProtKB=A0A8I3PGI2	Canis lupus familiaris	LDO
ORNAN\|Ensembl=ENSOANG00000032008.2\|UniProtKB=K7E7P0	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010002588.1\|UniProtKB=A0A8V0X6I0	Gallus gallus	O
CHICK\|Gene_ORFName=RCJMB04_33o10\|UniProtKB=Q5ZHS0	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000042829.1\|UniProtKB=A0A803TJS3	Anolis carolinensis	LDO
XENLA\|Gene=abraxas1\|UniProtKB=Q6GR31	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5730310\|UniProtKB=Q28HX0	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000022037.1\|UniProtKB=A0A3B3IMJ4	Oryzias latipes	LDO
DANRE\|Gene=abraxas2a\|UniProtKB=A0A8M9PTT5	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-041010-70\|UniProtKB=Q1LVP6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000012124.1\|UniProtKB=W5N2Q8	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000012898.2\|UniProtKB=F6PT97	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118413888\|UniProtKB=A0A9J7MMI9	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC589113\|UniProtKB=A0A7M7NSU8	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC754412\|UniProtKB=A0A7M7PDL2	Strongylocentrotus purpuratus	LDO
TRICA\|EnsemblGenome=TC032132\|UniProtKB=A0A139WMD4	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_227109\|UniProtKB=E9H423	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW009320\|UniProtKB=B7PYJ6	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g239133\|UniProtKB=A7RLH6	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG58498\|UniProtKB=B3S2V8	Trichoplax adhaerens	LDO
CHLRE\|EnsemblGenome=CHLRE_12g537700v5\|UniProtKB=A0A2K3D5A3	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00023p00049170\|UniProtKB=W1NJA3	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_141G00170\|UniProtKB=A0A0K9PZW7	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma05_g14260\|UniProtKB=A0A804J4B4	Musa acuminata subsp. malaccensis	LDO
SORBI\|EnsemblGenome=SORBI_3005G007700\|UniProtKB=C5Y320	Sorghum bicolor	O
SORBI\|EnsemblGenome=SORBI_3008G008300\|UniProtKB=A0A1B6PAR4	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb421620\|UniProtKB=A0A804RIL3	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb163300\|UniProtKB=A0A804NIR5	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os04g0479300\|UniProtKB=Q0JCC9	Oryza sativa	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0175640\|UniProtKB=F2ECW8	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS1A02G382300\|UniProtKB=A0A3B5Y6W3	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1B02G407600\|UniProtKB=A0A3B5Z3J9	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2D02G337200\|UniProtKB=A0A3B6DEP8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2B02G356400\|UniProtKB=A0A3B6CB20	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2A02G325500\|UniProtKB=A0A3B6B1K4	Triticum aestivum	O
ORYSJ\|EnsemblGenome=Os07g0540200\|UniProtKB=Q7XHK9	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_4g44770v3\|UniProtKB=I1IV51	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0465240\|UniProtKB=A0A8I6YQS9	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS5A02G151000\|UniProtKB=A0A3B6KDR6	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5D02G156000\|UniProtKB=A0A3B6MQT5	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5B02G149500\|UniProtKB=A0A3B6LIC2	Triticum aestivum	LDO
NELNU\|Gene=LOC104597264\|UniProtKB=A0A1U8A6L0	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110804770\|UniProtKB=A0A9R0JDL1	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr16g0742541\|UniProtKB=A0A251RY70	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C800429940\|UniProtKB=A0A9R1UNP8	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a011092mg\|UniProtKB=A0A022RPK3	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_23189\|UniProtKB=A0A1U8EDW3	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400017108\|UniProtKB=M1BFK9	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc09g015180.3\|UniProtKB=A0A3Q7I1B0	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107775552\|UniProtKB=A0A1S3YF45	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107798940\|UniProtKB=A0A1S4ALD9	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi08g00780\|UniProtKB=F6GXT4	Vitis vinifera	LDO
BRANA\|Gene_ORFName=DARMORV10_C05P59060.1\|UniProtKB=A0A078GTJ9	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A05P40020.1\|UniProtKB=A0A078HGN6	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra029720\|UniProtKB=A0A397ZFA0	Brassica campestris	LDO
ARATH\|TAIR=locus=2077798\|UniProtKB=Q8RY09	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107938952\|UniProtKB=A0A1U8MQA9	Gossypium hirsutum	O
GOSHI\|Gene=LOC107958085\|UniProtKB=A0A1U8PDH7	Gossypium hirsutum	O
GOSHI\|Gene=LOC107890935\|UniProtKB=A0A1U8HYD8	Gossypium hirsutum	O
GOSHI\|Gene=LOC107937069\|UniProtKB=A0A1U8MEW3	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_021595\|UniProtKB=A0A061EQX8	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g022036mg\|UniProtKB=A0A067FIK1	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_016G126200v3\|UniProtKB=B9IGH9	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_09G111300\|UniProtKB=A0A2C9V9Z4	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0848310\|UniProtKB=B9SL12	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_01G125600\|UniProtKB=I1J7I2	Glycine max	LDO
SOYBN\|EnsemblGenome=GLYMA_03G047200\|UniProtKB=A0A0R0KR12	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_4g014250\|UniProtKB=G7JKM8	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr03_26320\|UniProtKB=A0A2I4DPV0	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_4G314410\|UniProtKB=A0A0A0KY28	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_6G284500\|UniProtKB=A0A251NWZ3	Prunus persica	LDO
PHYPA\|EnsemblGenome=Pp3c3_16910\|UniProtKB=A9RSH0	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0060s0108\|UniProtKB=A0A2R6WT63	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_001730280\|UniProtKB=A0A1Y1HZF6	Klebsormidium nitens	LDO