PANTHER Gene Information

Gene Symbol(s):

Laptm4b

Organism:

Rattus norvegicus

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Gene Name:

Lysosomal-associated transmembrane protein 4B

Gene ID:

1311853

Protein ID:

Q5U1W4

Persistent Id:

PTN000280449

Alternate Ids:

81883433(GI)	LAP4B(Synonym)
ENSRNOG00000006766(Ensembl)	NM_001013174(refSeq)
AAH86442(EMBL-CDS)	BC086442(EMBL)
315047(GeneID)	ENSRNOP00000008969(Ensembl_PRO)
LAP4B_RAT(UniProtKB-ID)	1311853(RGD)
ENSRNOT00000008969(Ensembl_TRS)	Laptm4b{ECO:0000312\|RGD:1311853}(Symbol)
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PANTHER Classification

PANTHER Family:	LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN (PTHR12479)
PANTHER Subfamily:	LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN 4B (PTHR12479:SF6)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	lysosomal membrane
PANTHER protein class:	transporter

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ceramide binding, phosphatidylinositol bisphosphate binding, ubiquitin protein ligase binding, kinase binding
GO BP Complete:	negative regulation of lysosomal protein catabolic process, negative regulation of transforming growth factor beta1 production, regulation of lysosome organization, endosome organization, regulation of lysosomal membrane permeability, endosome transport via multivesicular body sorting pathway
GO CC Complete:	late endosome membrane, early endosome, multivesicular body, internal vesicle, endosome, multivesicular body membrane, cell projection, lysosomal membrane, plasma membrane, lysosome

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000045980.1\|UniProtKB=A0A2I3RQA7	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000042529.1\|UniProtKB=A0A2I2YED4	Gorilla gorilla gorilla	O
HUMAN\|HGNC=13646\|UniProtKB=Q86VI4	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000048729.1\|UniProtKB=A0A2I3S6V6	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000045677.1\|UniProtKB=A0A2I3TSM5	Pan troglodytes	LDO
PANTR\|Ensembl=ENSPTRG00000020448.6\|UniProtKB=H2QWH1	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000000543.3\|UniProtKB=G3QE49	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000008926.4\|UniProtKB=F7EW64	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1890494\|UniProtKB=Q91XQ6	Mus musculus	LDO
BOVIN\|Gene=LAPTM4B\|UniProtKB=Q71SV0	Bos taurus	LDO
BOVIN\|Ensembl=ENSBTAG00000053088.1\|UniProtKB=A0A3Q1MY65	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000046974.2\|UniProtKB=A0A3Q1LMY6	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000012254.5\|UniProtKB=F1MY67	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000016959.5\|UniProtKB=A6QQ25	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000006083.5\|UniProtKB=A0A480K595	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000020137.4\|UniProtKB=A0A3Q2ICC9	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000040131.3\|UniProtKB=A0A2I2U5F1	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845023537.1\|UniProtKB=A0A8I3S7G8	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000006848.4\|UniProtKB=A0A5F8GBV3	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000003683.3\|UniProtKB=F7DYY0	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010011556.1\|UniProtKB=A0A8V0YBJ6	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000015960.4\|UniProtKB=G1KRY2	Anolis carolinensis	LDO
XENLA\|Gene=laptm4b.S\|UniProtKB=A0A1L8FTJ9	Xenopus laevis	LDO
XENLA\|Gene=laptm4b.L\|UniProtKB=B1H1Y1	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-13579710\|UniProtKB=A0A6I8S9L7	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000002899.2\|UniProtKB=A0A3B3HN64	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000025607.1\|UniProtKB=A0A3B3H5A7	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030616-616\|UniProtKB=Q801V1	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000009853.1\|UniProtKB=W5MUI5	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118409848\|UniProtKB=A0A9J7KN74	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC105440581\|UniProtKB=A0A7M7NNF4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100890040\|UniProtKB=A0A7M7NNI9	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00014214\|UniProtKB=Q23393	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG16398\|UniProtKB=A8XNI9	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00277696\|UniProtKB=A0A2A6BJZ5	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00016262\|UniProtKB=Q95YE0	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00026695\|UniProtKB=A8WVS8	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00094692\|UniProtKB=A0A2A6BV48	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00007338\|UniProtKB=G5EEY1	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG06040\|UniProtKB=A8X116	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00277086\|UniProtKB=A0A2A6BYC2	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00016533\|UniProtKB=Q18527	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG16844\|UniProtKB=A8XPX6	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00089652\|UniProtKB=A0A2A6BEM6	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00008191\|UniProtKB=O45310	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG18791\|UniProtKB=A8XU46	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00112490\|UniProtKB=A0A454XTY0	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00017675\|UniProtKB=P91269	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00039466\|UniProtKB=A8XXX6	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00278537\|UniProtKB=A0A2A6C586	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00021060\|UniProtKB=Q23190	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG14761\|UniProtKB=A8XKM0	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00015494\|UniProtKB=L8E7Y1	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00034969\|UniProtKB=A8XK23	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00275435\|UniProtKB=A0A2A6BFK2	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00280703\|UniProtKB=A0A2A6D2R3	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0040777\|UniProtKB=Q7KGU6	Drosophila melanogaster	O
TRICA\|EnsemblGenome=TC006677\|UniProtKB=D6WYF0	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_310676\|UniProtKB=E9FV48	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_307524\|UniProtKB=E9H2M7	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW014133\|UniProtKB=B7QHE6	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG174805\|UniProtKB=T1F8I0	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g116948\|UniProtKB=A7SFY8	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG57979\|UniProtKB=B3S2D1	Trichoplax adhaerens	O