PANTHER Gene Information

Gene Symbol(s):

WIPI2

Organism:

Gallus gallus

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Gene Name:

WD repeat domain phosphoinositide-interacting protein 2

Gene ID:

ENSGALG00010021162

Protein ID:

Q5ZHN3

Persistent Id:

PTN000132200

Alternate Ids:

82233677(GI)	NM_001006162(refSeq)
WIPI2(Synonym)	WIPI2_CHICK(UniProtKB-ID)
CAG32760(EMBL-CDS)	ENSGALG00010021162(Ensembl)
ENSGALT00010051262(Ensembl_TRS)	AJ721101(EMBL)
416481(GeneID)	WIPI2(Symbol)
ENSGALP00010030453(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED (PTHR11227)
PANTHER Subfamily:	WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 2 (PTHR11227:SF27)
PANTHER GO-slim Molecular Function:	anion binding phosphatidylinositol-3-phosphate binding phosphatidylinositol bisphosphate binding
PANTHER GO-slim Biological Process:	autophagosome assembly protein localization autophagy of mitochondrion protein lipidation
PANTHER GO-slim Cellular Component:	cytosol extrinsic component of membrane phagophore assembly site
PANTHER protein class:	scaffold/adaptor protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	phosphatidylinositol-3,5-bisphosphate binding, phosphatidylinositol-3-phosphate binding
GO BP Complete:	autophagosome assembly, nucleophagy, protein localization to phagophore assembly site, protein lipidation, autophagy of peroxisome, cellular response to starvation, autophagy of mitochondrion, glycophagy
GO CC Complete:	phagophore assembly site membrane, cytosol, extrinsic component of membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Autophagy, Macroautophagy

Orthologs

ID	Organism	Type
HUMAN\|HGNC=32225\|UniProtKB=Q9Y4P8	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000018882.6\|UniProtKB=H2QU47	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000006240.3\|UniProtKB=G3S581	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000007045.4\|UniProtKB=F7F1A7	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1923831\|UniProtKB=Q80W47	Mus musculus	LDO
RAT\|RGD=1359154\|UniProtKB=Q6AY57	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000012049.4\|UniProtKB=Q2KJ60	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000007580.5\|UniProtKB=A0A5G2R553	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000022114.4\|UniProtKB=A0A9L0SQR7	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000009990.5\|UniProtKB=M3WCI0	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845013987.1\|UniProtKB=A0A8I3P1L5	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000044770.1\|UniProtKB=A0A5F8G717	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000036784.1\|UniProtKB=A0A5F8GBU1	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000024415.2\|UniProtKB=F7GFS3	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000039640.1\|UniProtKB=A0A5F8GTT2	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000028702.2\|UniProtKB=K7E1Z3	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000001936.3\|UniProtKB=F6VKC1	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000000956.4\|UniProtKB=F6UUB2	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000006569.4\|UniProtKB=F6WFA8	Ornithorhynchus anatinus	LDO
ANOCA\|Ensembl=ENSACAG00000014501.4\|UniProtKB=H9GL94	Anolis carolinensis	LDO
XENLA\|Gene=wipi2\|UniProtKB=Q7ZWU5	Xenopus laevis	LDO
XENTR\|Gene=wipi2\|UniProtKB=A0A8J1IWV1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000013601.2\|UniProtKB=H2MEQ1	Oryzias latipes	LDO
DANRE\|Gene=wipi2\|UniProtKB=A0A8M1P910	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000004511.1\|UniProtKB=W5MAJ8	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000004244.3\|UniProtKB=F6YG27	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118428714\|UniProtKB=A0A9J7M5W7	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC575901\|UniProtKB=A0A7M7NQS1	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00018294\|UniProtKB=O16466	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00024700\|UniProtKB=A8WQM3	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG01469\|UniProtKB=A8WQM1	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00102396\|UniProtKB=A0A2A6CRZ1	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0032935\|UniProtKB=Q9VIE1	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP007970\|UniProtKB=A0A1S4GXM5	Anopheles gambiae	O
DROME\|FlyBase=FBgn0035850\|UniProtKB=M9PER1	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP005910\|UniProtKB=Q7Q6D5	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC006217\|UniProtKB=D6WVG2	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_99438\|UniProtKB=E9G6W9	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW018244\|UniProtKB=B7PHQ2	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG189501\|UniProtKB=T1FR39	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG185812\|UniProtKB=T1FNB8	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g21829\|UniProtKB=A7SCQ4	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG20961\|UniProtKB=B3RQ37	Trichoplax adhaerens	LDO
YEAST\|SGD=S000006021\|UniProtKB=Q02887	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ABR189W\|UniProtKB=Q75D34	Eremothecium gossypii	O
YEAST\|SGD=S000001917\|UniProtKB=P43601	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AAL119W\|UniProtKB=Q75F47	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000201683\|UniProtKB=Q5AI22	Candida albicans	O
CANAL\|CGD=CAL0000198706\|UniProtKB=Q5ABA6	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_F27907g\|UniProtKB=Q6C044	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_00127\|UniProtKB=Q5BH53	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_5G11660\|UniProtKB=Q4WVD0	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU03441\|UniProtKB=Q96U88	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_09586\|UniProtKB=A7EW77	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_14035\|UniProtKB=Q0U2J8	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC823.16c\|UniProtKB=Q9P6N1	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_04963\|UniProtKB=B6K883	Schizosaccharomyces japonicus	O
SCHPO\|PomBase=SPAC589.07c\|UniProtKB=Q9HDZ7	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_01783\|UniProtKB=B6JYW2	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNE02750\|UniProtKB=P0CS28	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_04932\|UniProtKB=Q4P4N1	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_10397\|UniProtKB=E3KKV1	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_14943\|UniProtKB=F4PES2	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=EHI_152060\|UniProtKB=C4LSP5	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0285375\|UniProtKB=Q54NA2	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_33979\|UniProtKB=F0ZLV2	Dictyostelium purpureum	LDO
TRYB2\|Gene_ORFName=Tb10.389.1510\|UniProtKB=Q389C0	Trypanosoma brucei	LDO
TRIV3\|Gene_ORFName=TVAG_198640\|UniProtKB=A2DDP9	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_217070\|UniProtKB=A2F542	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_226490\|UniProtKB=A2ER83	Trichomonas vaginalis	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_1017\|UniProtKB=B8BT37	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GM26_PHYRM\|UniProtKB=H3GM26	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_10g457550v5\|UniProtKB=A8I0Q7	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00019p00100510\|UniProtKB=W1PGK3	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_388G00180\|UniProtKB=A0A0K9P4T7	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma09_g13030\|UniProtKB=A0A804KJ15	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_017545mg\|UniProtKB=K3YTF0	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3004G327100\|UniProtKB=A0A194YSU3	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb257610\|UniProtKB=A0A1D6HN15	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os02g0791800\|UniProtKB=Q6K9M2	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g53850v3\|UniProtKB=I1IDD3	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0623190\|UniProtKB=A0A8I7BCL0	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS6D02G335900\|UniProtKB=A0A3B6QLZ5	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6A02G353600\|UniProtKB=A0A3B6NWH2	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6B02G386200\|UniProtKB=A0A3B6PQV1	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_029006\|UniProtKB=A0A1U8BLW3	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110793573\|UniProtKB=A0A9R0K0Q0	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr09g0371321\|UniProtKB=A0A251TSC0	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C700362660\|UniProtKB=A0A9R1X2P5	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a008602mg\|UniProtKB=A0A022R0S1	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_33433\|UniProtKB=A0A2G2XYY5	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400011161\|UniProtKB=M1AS17	Solanum tuberosum	LDO
TOBAC\|Gene=LOC107781078\|UniProtKB=A0A1S3YXY1	Nicotiana tabacum	O
TOBAC\|Gene=LOC107798793\|UniProtKB=A0A1S4AKU0	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi11g00813\|UniProtKB=F6HYN1	Vitis vinifera	LDO
BRANA\|Gene_ORFName=DARMORV10_A03P59920.1\|UniProtKB=A0A078HL52	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra024070\|UniProtKB=M4E5L6	Brassica campestris	LDO
ARATH\|TAIR=locus=2118801\|UniProtKB=Q8H1Q8	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107957111\|UniProtKB=A0A1U8PA01	Gossypium hirsutum	O
GOSHI\|Gene=LOC107912975\|UniProtKB=A0A1U8K317	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_038453\|UniProtKB=A0A061GNU4	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g0193492mg\|UniProtKB=A0A067FFT8	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_018G101200v3\|UniProtKB=A0A2K1WYT2	Populus trichocarpa	LDO
RICCO\|Gene_ORFName=RCOM_0287180\|UniProtKB=B9T6W4	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_02G207500\|UniProtKB=K7K9T5	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_10G126200\|UniProtKB=K7LJ17	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_16G109400\|UniProtKB=A0A0R0FP94	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_17G070200\|UniProtKB=A0A0R0FIP9	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_4g130190\|UniProtKB=G7JED6	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr06_18070\|UniProtKB=A0A2I4EH26	Juglans regia	O
JUGRE\|EnsemblGenome=Jr06_18060\|UniProtKB=A0A2I4EH10	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_2G036700\|UniProtKB=A0A0A0LK48	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_1G100700\|UniProtKB=A0A251QVB2	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_176503\|UniProtKB=D8S386	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_233351\|UniProtKB=D8S802	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c7_8510\|UniProtKB=A9S1Y6	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0027s0044\|UniProtKB=A0A2R6X9Y4	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_004040130\|UniProtKB=A0A1Y1IC46	Klebsormidium nitens	LDO