PANTHER Gene Information   
Gene Symbol(s): Gnb3
Organism: Mus musculus
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Gene Name: Guanine nucleotide-binding protein G(I)_G(S)_G(T) subunit beta-3
Gene ID: MGI:95785
Protein ID: Q61011
Persistent Id: PTN000457595
Alternate Ids:
NP_038558(refSeq) AAB01725(EMBL-CDS)
ENSMUSG00000023439(Ensembl) 1353492(GI)
U38494(EMBL) 14695(GeneID)
ENSMUST00000024206(Ensembl_TRS) ENSMUSP00000024206(Ensembl_PRO)
Gnb3(Symbol) GBB3(Synonym)
GBB3_MOUSE(UniProtKB-ID) MGI:95785(MGI)
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PANTHER Classification
PANTHER Family: GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA (PTHR19850)
PANTHER Subfamily: GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)_G(S)_G(T) SUBUNIT BETA-3 (PTHR19850:SF31)  
PANTHER GO-slim Molecular Function: signaling receptor complex adaptor activity
PANTHER GO-slim Biological Process: G protein-coupled receptor signaling pathway
PANTHER GO-slim Cellular Component: cytoplasmic side of plasma membrane
cytoplasm
extrinsic component of membrane
catalytic complex
plasma membrane protein complex
PANTHER protein class: heterotrimeric G-protein
Pathway Categories: Beta3 adrenergic receptor signaling pathway
   G-Protein
Wnt signaling pathway
   G protein, beta subunit
Thyrotropin-releasing hormone receptor signaling pathway
   G-Protein
GABA-B receptor II signaling
   G protein, beta subunit
Histamine H1 receptor mediated signaling pathway
   G-Protein
Inflammation mediated by chemokine and cytokine signaling pathway
   G protein, beta and gamma subunit
5HT1 type receptor mediated signaling pathway
   G-protein
5HT4 type receptor mediated signaling pathway
   G-protein
Muscarinic acetylcholine receptor 1 and 3 signaling pathway
   Gq-protein
Dopamine receptor mediated signaling pathway
   G protein, beta subunit
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
   G protein-activated inward rectifying potassium channel
Gonadotropin-releasing hormone receptor pathway
   Gbeta
Endogenous cannabinoid signaling
   G protein, beta subunit
Beta1 adrenergic receptor signaling pathway
   G-Protein
PI3 kinase pathway
   G protein, beta and gamma subunit
5HT2 type receptor mediated signaling pathway
   G-protein
Enkephalin release
   Gi-protein
Opioid proenkephalin pathway
   G-protein
Enkephalin release
   Gs-protein
Angiotensin II-stimulated signaling through G proteins and beta-arrestin
   G-protein, beta subunit
Opioid prodynorphin pathway
   G-protein
Beta2 adrenergic receptor signaling pathway
   G-Protein
Histamine H2 receptor mediated signaling pathway
   G-Protein
Opioid proopiomelanocortin pathway
   G-protein
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
   Gi-protein
Metabotropic glutamate receptor group III pathway
   Gi-protein
Cortocotropin releasing factor receptor signaling pathway
   G-Protein
Metabotropic glutamate receptor group II pathway
   G-protein
Oxytocin receptor mediated signaling pathway
   G-Protein
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: spectrin binding, GTPase activity, GTPase binding, signaling receptor complex adaptor activity
GO BP Complete: regulation of glucose metabolic process, G protein-coupled receptor signaling pathway, signal transduction, regulation of hormone metabolic process, regulation of gene expression, regulation of fat cell differentiation, cell volume homeostasis, regulation of triglyceride metabolic process, regulation of cholesterol metabolic process, regulation of phospholipid metabolic process
GO CC Complete: dendrite, heterotrimeric G-protein complex, cytoplasm, cell body
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: G protein gated Potassium channels, Regulation of insulin secretion, G alpha (q) signalling events, GPCR downstream signalling, Integration of energy metabolism, Vasopressin regulates renal water homeostasis via Aquaporins, Signaling by Nuclear Receptors, Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits, Aquaporin-mediated transport, G-protein beta:gamma signalling, Protein folding, Thromboxane signalling through TP receptor, Adrenaline,noradrenaline inhibits insulin secretion, Presynaptic function of Kainate receptors, G beta:gamma signalling through PLC beta, Activation of kainate receptors upon glutamate binding, Glucagon-type ligand receptors, Opioid Signalling, Inwardly rectifying K+ channels, Signaling by WNT, Peptide hormone metabolism, G alpha (12/13) signalling events, Signal Transduction, Beta-catenin independent WNT signaling, Platelet homeostasis, Sensory perception of sweet, bitter, and umami (glutamate) taste, Glucagon-like Peptide-1 (GLP1) regulates insulin secretion, GPER1 signaling, G beta:gamma signalling through BTK, Potassium Channels, Sensory Perception, G alpha (z) signalling events, GPCR ligand binding, Transport of small molecules, G alpha (i) signalling events, GABA receptor activation, Class B/2 (Secretin family receptors), Incretin synthesis, secretion, and inactivation, G alpha (s) signalling events, GABA B receptor activation, Signal amplification, ADP signalling through P2Y purinoceptor 1, Sensory perception of taste, Transmission across Chemical Synapses, Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding, ESR-mediated signaling, Extra-nuclear estrogen signaling, Neuronal System, Chaperonin-mediated protein folding, Signaling by GPCR, Activation of G protein gated Potassium channels, Neurotransmitter receptors and postsynaptic signal transmission, Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1), G beta:gamma signalling through PI3Kgamma, ADP signalling through P2Y purinoceptor 12, Activation of GABAB receptors, Platelet activation, signaling and aggregation, Hemostasis, Thrombin signalling through proteinase activated receptors (PARs), Metabolism, G-protein activation, G beta:gamma signalling through CDC42, Prostacyclin signalling through prostacyclin receptor, Ca2+ pathway, Metabolism of proteins

Orthologs