PANTHER Gene Information   
Gene Symbol(s): Alas2
Organism: Rattus norvegicus
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Gene Name: 5-aminolevulinate synthase, erythroid-specific, mitochondrial
Gene ID: 2084
Protein ID: Q63147
Persistent Id: PTN001415450
Alternate Ids:
NM_013197(refSeq) D86297(EMBL)
Alas2(Symbol) Alase(Synonym)
6978485(GI) BAA13063(EMBL-CDS)
2084(RGD) 2.3.1.37 {ECO:0000269|PubMed:8407861}(EC)
HEM0_RAT(UniProtKB-ID) Q63895(AltAccession)
25748(GeneID)
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PANTHER Classification
PANTHER Family: CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE (PTHR13693)
PANTHER Subfamily: 5-AMINOLEVULINATE SYNTHASE, ERYTHROID-SPECIFIC, MITOCHONDRIAL (PTHR13693:SF58)  
PANTHER GO-slim Molecular Function: N-acyltransferase activity
PANTHER GO-slim Biological Process: protein metabolic process
heme biosynthetic process
erythrocyte differentiation
macromolecule biosynthetic process
PANTHER GO-slim Cellular Component: mitochondrion
PANTHER protein class: transaminase
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: pyridoxal phosphate binding, coenzyme A binding, 5-aminolevulinate synthase activity
GO BP Complete: maternal process involved in female pregnancy, heme biosynthetic process, lactation, hemoglobin biosynthetic process, erythrocyte development, protoporphyrinogen IX biosynthetic process, response to xenobiotic stimulus, response to benzene, intracellular iron ion homeostasis, liver regeneration, response to hypoxia, erythrocyte differentiation, response to cobalt ion, response to fatty acid, response to lead ion
GO CC Complete: mitochondrial matrix, mitochondrion, mitochondrial inner membrane
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Metabolism, Metabolism of porphyrins, Heme biosynthesis

Orthologs