PANTHER Gene Information

Gene Symbol(s):

zgc:91929

Organism:

Danio rerio

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Gene Name:

Dual specificity protein phosphatase

Gene ID:

ZDB-GENE-040801-188

Protein ID:

Q6DBR5

Persistent Id:

PTN000017081

Alternate Ids:

BC078397(EMBL)	445057(GeneID)
Q6DBR5_DANRE(UniProtKB-ID)	182890976(GI)
ENSDARG00000098108(Ensembl)	NP_001003451(refSeq)
Q6DBR5(Synonym)	AAI63999(EMBL-CDS)
ENSDARP00000133300(Ensembl_PRO)	ENSDART00000163598(Ensembl_TRS)
ZDB-GENE-040801-188(ZFIN)
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PANTHER Classification

PANTHER Family:	DUAL SPECIFICITY PROTEIN PHOSPHATASE (PTHR10159)
PANTHER Subfamily:	DUAL SPECIFICITY PROTEIN PHOSPHATASE 2 (PTHR10159:SF109)
PANTHER GO-slim Molecular Function:	phosphoprotein phosphatase activity
PANTHER GO-slim Biological Process:	negative regulation of MAPK cascade protein dephosphorylation endoderm formation
PANTHER GO-slim Cellular Component:	cytoplasm nucleus
PANTHER protein class:	protein phosphatase

Pathway Categories:

Oxidative stress response

Mitogen activated protein kinase phosphatase 5

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	protein serine/threonine phosphatase activity, phosphoprotein phosphatase activity, protein tyrosine phosphatase activity, MAP kinase tyrosine/serine/threonine phosphatase activity, hydrolase activity, myosin phosphatase activity
GO BP Complete:	signal transduction, negative regulation of MAPK cascade, protein dephosphorylation, endoderm formation, dephosphorylation, negative regulation of JNK cascade, axon regeneration
GO CC Complete:	nucleus, cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

RAF-independent MAPK1/3 activation, MAPK1/MAPK3 signaling, Signal Transduction, MAPK family signaling cascades, RAF/MAP kinase cascade, Negative regulation of MAPK pathway

Orthologs

ID	Organism	Type
HUMAN\|HGNC=3068\|UniProtKB=Q05923	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000052076.1\|UniProtKB=K7C7C3	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000011069.3\|UniProtKB=G3R650	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000049314.1\|UniProtKB=A0A5F8AUL7	Macaca mulatta	LDO
MOUSE\|MGI=MGI=101911\|UniProtKB=Q05922	Mus musculus	LDO
RAT\|RGD=1305804\|UniProtKB=Q5M863	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000020350.6\|UniProtKB=F1MP34	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000035971.3\|UniProtKB=A0A286ZMV8	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000007242.4\|UniProtKB=F7BUD3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000010694.6\|UniProtKB=M3WDR4	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845006226.1\|UniProtKB=A0A8I3N0J1	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000008288.2\|UniProtKB=F6YIH7	Monodelphis domestica	LDO
ANOCA\|Ensembl=ENSACAG00000040611.1\|UniProtKB=A0A803TEZ8	Anolis carolinensis	LDO
ORYLA\|Ensembl=ENSORLG00000003043.2\|UniProtKB=H2LD04	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000015652.1\|UniProtKB=W5NF57	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000007986.3\|UniProtKB=F7ATJ8	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118413453\|UniProtKB=A0A9J7KYM6	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC579231\|UniProtKB=A0A7M7GGH4	Strongylocentrotus purpuratus	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g81300\|UniProtKB=A7RGX7	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG14780\|UniProtKB=B3S3C2	Trichoplax adhaerens	LDO
CRYNJ\|EnsemblGenome=CNB03810\|UniProtKB=Q5KLW5	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_02303\|UniProtKB=A0A0D1E1H7	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_04707\|UniProtKB=E3K3U9	Puccinia graminis	LDO
DICDI\|dictyBase=DDB_G0271350\|UniProtKB=Q55BI8	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_55591\|UniProtKB=F0ZMS0	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_08_0100\|UniProtKB=Q4QIF9	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb927.5.3620\|UniProtKB=Q57UA4	Trypanosoma brucei	LDO
PARTE\|EnsemblGenome=GSPATT00012095001\|UniProtKB=A0D0H6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00015531001\|UniProtKB=A0DC86	Paramecium tetraurelia	LDO