PANTHER Gene Information

Gene Symbol(s):

sox3

Organism:

Danio rerio

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Gene Name:

Transcription factor Sox-3

Gene ID:

ZDB-GENE-980526-333

Protein ID:

Q6EJB7

Persistent Id:

PTN000030805

Alternate Ids:

30529(GeneID)	ZDB-GENE-980526-333(ZFIN)
AB242330(EMBL)	SOX3(Synonym)
AAH92845(EMBL-CDS)	SOX3_DANRE(UniProtKB-ID)
NP_001001811(refSeq)	Q762C1(AltAccession)
sox3{ECO:0000312\|ZFIN:ZDB-GENE-980526-333}(Symbol)	82183737(GI)
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PANTHER Classification

PANTHER Family:	SOX TRANSCRIPTION FACTOR (PTHR10270)
PANTHER Subfamily:	TRANSCRIPTION FACTOR SOX-3 (PTHR10270:SF111)
PANTHER GO-slim Molecular Function:	DNA-binding transcription activator activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding
PANTHER GO-slim Biological Process:	negative regulation of transcription by RNA polymerase II neuron differentiation brain development positive regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	HMG box transcription factor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA binding, DNA-binding transcription factor activity, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific
GO BP Complete:	negative regulation of transcription by RNA polymerase II, central nervous system development, neuron differentiation, regulation of DNA-templated transcription, peripheral nervous system development, brain development, positive regulation of transcription by RNA polymerase II, positive regulation of DNA-binding transcription factor activity, otic placode formation, otic placode development, ovarian follicle development, regulation of transcription by RNA polymerase II
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Signaling by WNT, TCF dependent signaling in response to WNT, Deactivation of the beta-catenin transactivating complex, Signal Transduction

Orthologs

ID	Organism	Type
HUMAN\|HGNC=11199\|UniProtKB=P41225	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000044005.1\|UniProtKB=A0A2I3TQ10	Pan troglodytes	LDO
MACMU\|Ensembl=ENSMMUG00000013179.4\|UniProtKB=F6XQU8	Macaca mulatta	LDO
MOUSE\|MGI=MGI=98365\|UniProtKB=P53784	Mus musculus	LDO
RAT\|RGD=1591839\|UniProtKB=A0A8I5ZM42	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000049481.1\|UniProtKB=A0A3Q1MUX6	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000022501.3\|UniProtKB=I3LG51	Sus scrofa	LDO
CANLF\|Ensembl=ENSCAFG00845030422.1\|UniProtKB=A0A8I3Q427	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000013932.3\|UniProtKB=F6SCS3	Monodelphis domestica	LDO
ORYLA\|Ensembl=ENSORLG00000001780.2\|UniProtKB=Q9PT76	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000017493.1\|UniProtKB=W5NLT9	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000006005.3\|UniProtKB=F6T302	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000019315.1\|UniProtKB=Q4H2S2	Ciona intestinalis	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_263176\|UniProtKB=Q0Q578	Branchiostoma floridae	O
BRAFL\|Gene=LOC118427232\|UniProtKB=Q0Q579	Branchiostoma floridae	O
STRPU\|EnsemblGenome=GeneID_373201\|UniProtKB=Q9Y0D8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=GeneID_373202\|UniProtKB=Q9Y0D7	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00004950\|UniProtKB=Q20201	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00029569\|UniProtKB=A8X4J1	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00004949\|UniProtKB=Q21305	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00036570\|UniProtKB=A8XPM5	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00096578\|UniProtKB=A0A2A6B5A0	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00089564\|UniProtKB=A0A2A6BFP9	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0042630\|UniProtKB=M9PCG2	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP010922\|UniProtKB=A0A1S4H699	Anopheles gambiae	O
DROME\|FlyBase=FBgn0029123\|UniProtKB=M9PCZ7	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0000411\|UniProtKB=Q24533	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0036411\|UniProtKB=M9PFG6	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP009957\|UniProtKB=Q7PMD4	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP029652\|UniProtKB=A0A453Z0E6	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC013163\|UniProtKB=D6WND4	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC013165\|UniProtKB=D6WND2	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC014065\|UniProtKB=D6WK03	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC013166\|UniProtKB=D6WND1	Tribolium castaneum	O
IXOSC\|EnsemblGenome=ISCW007308\|UniProtKB=B7PUB6	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW006248\|UniProtKB=B7PLH0	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW000242\|UniProtKB=B7P775	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW023383\|UniProtKB=B7QK34	Ixodes scapularis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g235967\|UniProtKB=A7SUF3	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g207820\|UniProtKB=A7S716	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g243069\|UniProtKB=Q3S381	Nematostella vectensis	O
YEAST\|SGD=S000006269\|UniProtKB=P25042	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ADL331C\|UniProtKB=Q75B97	Eremothecium gossypii	O
CANAL\|CGD=CAL0000179598\|UniProtKB=Q5A220	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_B02266g\|UniProtKB=Q6CFZ3	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_D22660g\|UniProtKB=Q6C851	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_01962\|UniProtKB=Q5BBW8	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_4G10820\|UniProtKB=Q4WPX7	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU03481\|UniProtKB=Q1K507	Neurospora crassa	O
EMENI\|EnsemblGenome=ANIA_03549\|UniProtKB=Q5B7D1	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_04734\|UniProtKB=C8VAU1	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_4G12410\|UniProtKB=Q4WQD2	Neosartorya fumigata	O
ASPFU\|EnsemblGenome=AFUA_3G06170\|UniProtKB=Q4WWK2	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU02326\|UniProtKB=Q7S4T8	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_04006\|UniProtKB=A7EFB5	Sclerotinia sclerotiorum	O
SCHPO\|PomBase=SPBC23G7.09\|UniProtKB=P0CY17	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_05153\|UniProtKB=B6K8G9	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNM02020\|UniProtKB=Q5K7L5	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_12033\|UniProtKB=A0A0D1BUZ6	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_06975\|UniProtKB=E3KAW4	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_16202\|UniProtKB=E3L027	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_17717\|UniProtKB=E3L4J2	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_28269\|UniProtKB=F4PDI5	Batrachochytrium dendrobatidis	O
TRIV3\|Gene_ORFName=TVAG_172880\|UniProtKB=A2DF38	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_142450\|UniProtKB=A2EHK4	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_463800\|UniProtKB=A2E233	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_280760\|UniProtKB=A2DRJ7	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_180150\|UniProtKB=A2EE44	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_010230\|UniProtKB=A2FA38	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_110110\|UniProtKB=A2DGL2	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_344020\|UniProtKB=A2E7M3	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_201900\|UniProtKB=A2DWL1	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_414220\|UniProtKB=A2EC93	Trichomonas vaginalis	O