PANTHER Gene Information

Gene Symbol(s):

CYP2C18

Organism:

Macaca mulatta

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Gene Name:

Cytochrome P450 CYP2C75

Gene ID:

ENSMMUG00000018330.4

Protein ID:

Q6GUQ6

Persistent Id:

PTN009090387

Alternate Ids:

Q6GUQ6(Synonym)	NP_001035301(refSeq)
ENSMMUT00000000178(Ensembl_TRS)	AY635463(EMBL)
678686(GeneID)	ENSMMUP00000000166(Ensembl_PRO)
AAT49267(EMBL-CDS)	Q6GUQ6_MACMU(UniProtKB-ID)
ENSMMUG00000018330(Ensembl)	49066331(GI)
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PANTHER Classification

PANTHER Family:	CYTOCHROME P450 508A4-RELATED (PTHR24300)
PANTHER Subfamily:	CYTOCHROME P450 2C9 (PTHR24300:SF400)
PANTHER GO-slim Molecular Function:	monooxygenase activity heme binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
PANTHER GO-slim Biological Process:	cellular response to chemical stimulus organic acid metabolic process
PANTHER GO-slim Cellular Component:	intracellular membrane-bounded organelle cytoplasm
PANTHER protein class:	oxygenase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	arachidonate epoxygenase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen, iron ion binding, oxidoreductase activity, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, metal ion binding, steroid hydroxylase activity, caffeine oxidase activity, monooxygenase activity, heme binding
GO BP Complete:	organic acid metabolic process, urea metabolic process, estrogen metabolic process, epoxygenase P450 pathway, xenobiotic metabolic process, monoterpenoid metabolic process, steroid metabolic process, xenobiotic catabolic process, icosanoid biosynthetic process, oxidative demethylation, monocarboxylic acid metabolic process
GO CC Complete:	endoplasmic reticulum membrane, cytoplasm, intracellular membrane-bounded organelle, endoplasmic reticulum, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=2621\|UniProtKB=P33261	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000002779.5\|UniProtKB=A0A2I3RMB5	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000000057.4\|UniProtKB=G3QCV6	Gorilla gorilla gorilla	O
HUMAN\|HGNC=2623\|UniProtKB=P11712	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000002780.6\|UniProtKB=H2Q2B1	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000015433.4\|UniProtKB=G3RHD9	Gorilla gorilla gorilla	LDO
MOUSE\|MGI=MGI=1919553\|UniProtKB=Q148B1	Mus musculus	O
MOUSE\|MGI=MGI=1917138\|UniProtKB=Q5GLZ0	Mus musculus	LDO
RAT\|RGD=6488119\|UniProtKB=A0A8I6AFV7	Rattus norvegicus	LDO
RAT\|RGD=2469\|UniProtKB=P08683	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000049120.1\|UniProtKB=F1N6N4	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000053354.1\|UniProtKB=F1MEU8	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000037795.3\|UniProtKB=A0A3S5ZP79	Bos taurus	LDO
HORSE\|Ensembl=ENSECAG00000056239.1\|UniProtKB=A0A9L0T4Q6	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000039250.3\|UniProtKB=A0A3Q2HNV3	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000038251.3\|UniProtKB=F6W4J7	Equus caballus	LDO
MONDO\|Ensembl=ENSMODG00000011252.4\|UniProtKB=A0A5F8GA47	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000005516.4\|UniProtKB=F7CGP7	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000011489.4\|UniProtKB=F6V1R8	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000010204.4\|UniProtKB=F6SAU5	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000025781.3\|UniProtKB=F7FSV0	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000005361.4\|UniProtKB=F6YL42	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000005439.4\|UniProtKB=F7D0J8	Monodelphis domestica	LDO
LEPOC\|Ensembl=ENSLOCG00000014781.1\|UniProtKB=W5NC46	lepisosteus oculatus	O
CAEEL\|WormBase=WBGene00007913\|UniProtKB=P90771	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00026819\|UniProtKB=A8WW56	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00094501\|UniProtKB=A0A8R1Y7A5	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00098125\|UniProtKB=A0A454XRQ2	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00284156\|UniProtKB=A0A2A6CKC1	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00096193\|UniProtKB=A0A2A6CME8	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00100674\|UniProtKB=A0A2A6BLU9	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00100368\|UniProtKB=A0A2A6CNE7	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00274158\|UniProtKB=A0A2A6BNU3	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00115359\|UniProtKB=A0A2A6CNT1	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00115644\|UniProtKB=A0A2A6BLK1	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00277971\|UniProtKB=A0A2A6CEQ5	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00100681\|UniProtKB=A0A2A6CJP7	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00098124\|UniProtKB=A0A2A6BLN1	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00015135\|UniProtKB=Q27465	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00034232\|UniProtKB=A8XHN9	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00097800\|UniProtKB=A0A2A6BZL5	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00011698\|UniProtKB=O62378	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00011699\|UniProtKB=O62377	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00038021\|UniProtKB=A8XTS5	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00015040\|UniProtKB=O44655	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00024531\|UniProtKB=A8WQ01	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00015400\|UniProtKB=O02628	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00015399\|UniProtKB=O02627	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00019565\|UniProtKB=Q9N5I1	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00019473\|UniProtKB=O44649	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00016786\|UniProtKB=O16220	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG01388\|UniProtKB=A8WQA7	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00032566\|UniProtKB=A8XCZ4	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00024637\|UniProtKB=A8WQA9	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00015041\|UniProtKB=O44656	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00015043\|UniProtKB=O44658	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00015042\|UniProtKB=O44657	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00015044\|UniProtKB=H2KY69	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG01271\|UniProtKB=A8WQ03	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG01339\|UniProtKB=A8WQ64	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00024639\|UniProtKB=A8WQB1	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG01270\|UniProtKB=A8WQ02	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00019470\|UniProtKB=O44652	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00019472\|UniProtKB=O44650	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00019471\|UniProtKB=O44651	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00024632\|UniProtKB=A8WQA4	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00024638\|UniProtKB=A8WQB0	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00015709\|UniProtKB=Q27470	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG17010\|UniProtKB=A8XQ93	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00016092\|UniProtKB=Q27471	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG19168\|UniProtKB=A8XUZ8	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00008829\|UniProtKB=O45364	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG22835\|UniProtKB=A8Y360	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00041296\|UniProtKB=A8Y357	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00016686\|UniProtKB=O44704	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00016697\|UniProtKB=O44706	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00030566\|UniProtKB=A8X7I8	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG21837\|UniProtKB=A8Y0X9	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00040506\|UniProtKB=A8Y0W6	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00018334\|UniProtKB=Q27499	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00016768\|UniProtKB=Q27482	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00026374\|UniProtKB=A8WV77	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG03499\|UniProtKB=A8WV94	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00018262\|UniProtKB=O16670	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00019967\|UniProtKB=O02641	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00018261\|UniProtKB=O16671	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00018264\|UniProtKB=A0A0M7RF98	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00018413\|UniProtKB=O16362	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00024506\|UniProtKB=A8WPX6	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG01236\|UniProtKB=A8WPX1	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00021168\|UniProtKB=Q9N4Q4	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG01257\|UniProtKB=A8WPZ0	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00015045\|UniProtKB=O61204	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00024534\|UniProtKB=A8WQ04	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00007362\|UniProtKB=G5ECD0	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG11445\|UniProtKB=A8XD01	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00010589\|UniProtKB=O45659	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00012448\|UniProtKB=G5EE22	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00029469\|UniProtKB=A8X4U1	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00020386\|UniProtKB=O61935	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00024530\|UniProtKB=A8WQ00	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00016860\|UniProtKB=O16482	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00021710\|UniProtKB=Q965T7	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00018260\|UniProtKB=O16673	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG06337\|UniProtKB=A8X201	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG06602\|UniProtKB=A8X2M4	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00095332\|UniProtKB=A0A2A6C4I1	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00091774\|UniProtKB=A0A8R1YBK8	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00101192\|UniProtKB=A0A2A6BY51	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00284432\|UniProtKB=A0A2A6BX43	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00280176\|UniProtKB=A0A2A6CNR8	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00115306\|UniProtKB=A0A2A6BJ45	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00100939\|UniProtKB=A0A2A6C207	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00115307\|UniProtKB=A0A2A6BJ16	Pristionchus pacificus	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g234969\|UniProtKB=A7S5T4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g204234\|UniProtKB=A7RYZ5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g208281\|UniProtKB=A7S865	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g171703\|UniProtKB=A7SKW0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g164344\|UniProtKB=A7RYZ4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g143569\|UniProtKB=A7T2W8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g122119\|UniProtKB=A7SKW3	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g122140\|UniProtKB=A7SKW2	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g231218\|UniProtKB=A7SZN0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g227345\|UniProtKB=A7SNF8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g60849\|UniProtKB=A7RWT2	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g238893\|UniProtKB=A7RK94	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g82634\|UniProtKB=A7RI92	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g209361\|UniProtKB=A7SAR4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g221914\|UniProtKB=A7T3R2	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g107875\|UniProtKB=A7S7U4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g161477\|UniProtKB=A7RQ60	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g13146\|UniProtKB=A7S7V0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g182833\|UniProtKB=A7RWT1	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g217770\|UniProtKB=A7SUQ2	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g235065\|UniProtKB=A7S7U0	Nematostella vectensis	O
DICDI\|dictyBase=DDB_G0272704\|UniProtKB=Q86A22	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_42091\|UniProtKB=F1A1D7	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0271778\|UniProtKB=Q55AJ4	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_92019\|UniProtKB=F0ZKM6	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0282283\|UniProtKB=Q54SV9	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_81297\|UniProtKB=F0ZT26	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_99050\|UniProtKB=F0ZVS1	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0286743\|UniProtKB=Q54LA8	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_17677\|UniProtKB=F0ZHS5	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0282769\|UniProtKB=Q1ZXG3	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0292168\|UniProtKB=Q54DT2	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_153109\|UniProtKB=F0ZN31	Dictyostelium purpureum	O