PANTHER Gene Information

Gene Symbol(s):

zgc:66101

Organism:

Danio rerio

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Gene Name:

Serine_threonine-protein kinase SIK3 homolog

Gene ID:

ZDB-GENE-140106-203

Protein ID:

Q6NSM8

Persistent Id:

PTN001966396

Alternate Ids:

BC070022(EMBL)	47123268(GI)
Q6PHV1(AltAccession)	SIK3_DANRE(UniProtKB-ID)
393513(GeneID)	AAH70022(EMBL-CDS)
ZDB-GENE-140106-203(ZFIN)	NP_956835(refSeq)
2.7.11.1(EC)	SIK3(Synonym)
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PANTHER Classification

PANTHER Family:	MAP/MICROTUBULE AFFINITY-REGULATING KINASE (PTHR24346)
PANTHER Subfamily:	SERINE_THREONINE-PROTEIN KINASE SIK3 (PTHR24346:SF42)
PANTHER GO-slim Molecular Function:	protein serine/threonine kinase activity
PANTHER GO-slim Biological Process:	intracellular signal transduction microtubule cytoskeleton organization
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	non-receptor serine/threonine protein kinase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	nucleotide binding, magnesium ion binding, tau-protein kinase activity, ATP binding, metal ion binding, protein kinase activity, protein serine/threonine kinase activity, transferase activity, kinase activity, protein serine kinase activity
GO BP Complete:	microtubule cytoskeleton organization, phosphorylation, protein phosphorylation, intracellular signal transduction
GO CC Complete:	cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=29165\|UniProtKB=Q9Y2K2	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000045188.1\|UniProtKB=A0A2I3SAF3	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000004317.7\|UniProtKB=H2R4Y2	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000011085.3\|UniProtKB=A0A2I2ZLH2	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000016128.4\|UniProtKB=A0A1D5Q6B4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2446296\|UniProtKB=Q6P4S6	Mus musculus	LDO
RAT\|RGD=1593938\|UniProtKB=M0RD40	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000015119.5\|UniProtKB=F1MXE2	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000015071.5\|UniProtKB=A0A8W4FQH7	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000010252.4\|UniProtKB=F6PH61	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000008202.6\|UniProtKB=A0A2I2UYU7	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845004222.1\|UniProtKB=A0A8I3MPH9	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000013784.5\|UniProtKB=F6TUU1	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000015712.4\|UniProtKB=F7EFA6	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010024788.1\|UniProtKB=A0A8V1A7E9	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000001502.4\|UniProtKB=H9G5C1	Anolis carolinensis	LDO
XENLA\|Gene=sik3.L\|UniProtKB=A0A1L8FLN0	Xenopus laevis	O
XENLA\|Gene=sik3.S\|UniProtKB=A0A1L8FFU9	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-6042192\|UniProtKB=A0A6I8SYZ1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000015807.2\|UniProtKB=H2MM62	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000001801.1\|UniProtKB=W5M158	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118420045\|UniProtKB=A0A9J7LGV7	Branchiostoma floridae	O
BRAFL\|Gene=LOC118408898\|UniProtKB=A0A9J7KLS0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118429760\|UniProtKB=A0A9J7M8D2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118419915\|UniProtKB=A0A9J7MXL4	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC593886\|UniProtKB=A0A7M7NAU9	Strongylocentrotus purpuratus	LDO
PRIPA\|EnsemblGenome=WBGene00109828\|UniProtKB=A0A2A6CUZ0	Pristionchus pacificus	LDO
ANOGA\|EnsemblGenome=AGAP029812\|UniProtKB=A0A499FWX1	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC015081\|UniProtKB=D2A600	Tribolium castaneum	LDO
HELRO\|EnsemblGenome=HelroG131017\|UniProtKB=T1EHV0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG73300\|UniProtKB=T1G1C6	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g139527\|UniProtKB=A7SZV3	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG27001\|UniProtKB=B3S0C9	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_34468\|UniProtKB=A9VBY4	Monosiga brevicollis	O
CANAL\|CGD=CAL0000177153\|UniProtKB=A0A1D8PRN8	Candida albicans	O
ASPFU\|EnsemblGenome=AFUA_1G11080\|UniProtKB=Q4WSZ7	Neosartorya fumigata	O
SCHJY\|EnsemblGenome=SJAG_02838\|UniProtKB=B6K1B3	Schizosaccharomyces japonicus	O
ASPFU\|EnsemblGenome=AFUA_1G11930\|UniProtKB=E9RDZ3	Neosartorya fumigata	O
SCHJY\|EnsemblGenome=SJAG_04469\|UniProtKB=B6K6W9	Schizosaccharomyces japonicus	O
SCHJY\|EnsemblGenome=SJAG_03602\|UniProtKB=B6K4P0	Schizosaccharomyces japonicus	O
BATDJ\|Gene_ORFName=BATDEDRAFT_10042\|UniProtKB=F4NZ62	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_073490\|UniProtKB=C4LXL3	Entamoeba histolytica	O
ENTH1\|Gene_ORFName=EHI_025300\|UniProtKB=A0A8U0WP54	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0280133\|UniProtKB=Q54VU4	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_151676\|UniProtKB=F0ZJH1	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0292304\|UniProtKB=Q54DF2	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_51418\|UniProtKB=F1A3P4	Dictyostelium purpureum	O
GIAIC\|EnsemblGenome=GL50803_9487\|UniProtKB=A8B530	Giardia intestinalis	O
PLAF7\|EnsemblGenome=PF3D7_1441300\|UniProtKB=Q8IL57	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00031618001\|UniProtKB=A0BS70	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00002297001\|UniProtKB=A0DGK1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00020040001\|UniProtKB=A0DTJ2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00018964001\|UniProtKB=A0DP01	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00030300001\|UniProtKB=A0BM97	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00004376001\|UniProtKB=A0BCL5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00018952001\|UniProtKB=A0DNY9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00026401001\|UniProtKB=A0EFI7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00024498001\|UniProtKB=A0E900	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00024481001\|UniProtKB=A0E8Y3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00017966001\|UniProtKB=A0DKR9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028068001\|UniProtKB=A0BER8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00022278001\|UniProtKB=A0E1E2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00009964001\|UniProtKB=A0CSC5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00025088001\|UniProtKB=A0EAN7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00029968001\|UniProtKB=A0BLB9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00014139001\|UniProtKB=A0D805	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00019068001\|UniProtKB=A0DPB9	Paramecium tetraurelia	O
PHYRM\|Gene=H3H0P0_PHYRM\|UniProtKB=H3H0P0	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_07g329850v5\|UniProtKB=A0A2K3DJR9	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_09g403850v5\|UniProtKB=A0A2K3DCM7	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_13g568050v5\|UniProtKB=A0A2K3CZG1	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_16g685389v5\|UniProtKB=A0A2K3CW32	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_02g076000v5\|UniProtKB=A0A2K3E058	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_01g036000v5\|UniProtKB=A0A2K3E716	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_06g251050v5\|UniProtKB=A0A2K3DLY4	Chlamydomonas reinhardtii	O
HELAN\|Gene_ORFName=HanXRQr2_Chr05g0231561\|UniProtKB=A0A9K3J1W2	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C500236580\|UniProtKB=A0A9R1XB86	Lactuca sativa	O
KLENI\|Gene_ORFName=KFL_000330150\|UniProtKB=A0A1Y1HQV7	Klebsormidium nitens	O
LACSA\|Gene_ORFName=LSAT_V11C400212270\|UniProtKB=A0A9R1XHY6	Lactuca sativa	O
KLENI\|Gene_ORFName=KFL_000980330\|UniProtKB=A0A0U9HJG2	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_007820030\|UniProtKB=A0A1Y1IQA2	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_001250250\|UniProtKB=A0A1Y1I3Z9	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_000970360\|UniProtKB=A0A0U9HJE6	Klebsormidium nitens	O
MUSAM\|EnsemblGenome=Ma01_g02460\|UniProtKB=A0A804HPI0	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma00_g00400\|UniProtKB=A0A804HLY2	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma10_g08280\|UniProtKB=A0A804KTZ1	Musa acuminata subsp. malaccensis	O
MAIZE\|EnsemblGenome=Zm00001eb013270\|UniProtKB=Q6RXY1	Zea mays	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0320770\|UniProtKB=A0A8I7BB45	Hordeum vulgare subsp. vulgare	O
SETIT\|EnsemblGenome=SETIT_019716mg\|UniProtKB=K3YZK6	Setaria italica	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0060110\|UniProtKB=A0A8I6X3U9	Hordeum vulgare subsp. vulgare	O
MAIZE\|EnsemblGenome=Zm00001eb293240\|UniProtKB=A0A804Q4X7	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb353700\|UniProtKB=A0A804QSJ7	Zea mays	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0286490\|UniProtKB=A0A8I6XFN7	Hordeum vulgare subsp. vulgare	O
SPIOL\|Gene=LOC110800356\|UniProtKB=A0A9R0J5M8	Spinacia oleracea	O
HELAN\|Gene_ORFName=HanXRQr2_Chr07g0308661\|UniProtKB=A0A9K3ING8	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C900467660\|UniProtKB=A0A9R1UGU9	Lactuca sativa	O
PHYPA\|EnsemblGenome=Pp3c3_5570\|UniProtKB=A0A7I4DGQ5	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0038s0082\|UniProtKB=A0A2R6X3U9	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0160s0010\|UniProtKB=A0A2R6W3Y3	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_008220030\|UniProtKB=A0A1Y1INE1	Klebsormidium nitens	O
STRCO\|Gene_OrderedLocusName=SCO4820\|UniProtKB=Q9K3K0	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO4817\|UniProtKB=Q9K3K3	Streptomyces coelicolor	O
DEIRA\|EnsemblGenome=DR_1213\|UniProtKB=Q9RV17	Deinococcus radiodurans	O
RHOBA\|EnsemblGenome=RB12694\|UniProtKB=Q7UI82	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_576\|UniProtKB=O66844	Aquifex aeolicus	O