PANTHER Gene Information

Gene Symbol(s):

SLC18B1

Organism:

Homo sapiens

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Gene Name:

MFS-type transporter SLC18B1

Gene ID:

HGNC:21573

Protein ID:

Q6NT16

Enhancers:

View enhancers for HUMAN|HGNC=21573|UniProtKB=Q6NT16

Genetic Variant Annotation:

Annoq

Persistent Id:

PTN002512355

Alternate Ids:

AAH69567(EMBL-CDS)	119568398(GI)
116843(GeneID)	AL032821(EMBL)
C6orf192(Synonym)	613361(MIM)
A8K1K3(AltAccession)	S18B1_HUMAN(UniProtKB-ID)
ENSG00000146409(Ensembl)	NP_439896(refSeq)
ENST00000275227(Ensembl_TRS)	HGNC:21573(HGNC)
ENSP00000275227(Ensembl_PRO)	SLC18B1{ECO:0000303\|PubMed:25355561}(Symbol)
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PANTHER Classification

PANTHER Family:	GH10249P (PTHR23506)
PANTHER Subfamily:	MFS-TYPE TRANSPORTER SLC18B1 (PTHR23506:SF26)
PANTHER GO-slim Molecular Function:	transmembrane transporter activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	secondary carrier transporter

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	polyamine:proton antiporter activity, monoamine:proton antiporter activity, transmembrane transporter activity
GO BP Complete:	serotonin uptake, spermine transport, polyamine transmembrane transport, proton transmembrane transport, spermidine transport
GO CC Complete:	secretory granule membrane, synaptic vesicle membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000018616.7\|UniProtKB=H2QTR7	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000007215.3\|UniProtKB=G3QWA7	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000013236.4\|UniProtKB=A0A5F8A948	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1923556\|UniProtKB=D3Z5L6	Mus musculus	LDO
RAT\|RGD=1306962\|UniProtKB=D4A9K4	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000015242.6\|UniProtKB=E1BHT6	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000004178.5\|UniProtKB=F1S3R0	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000023651.4\|UniProtKB=F7CJ96	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000011135.6\|UniProtKB=M3WEJ5	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845004799.1\|UniProtKB=A0A8I3N9X2	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000017522.4\|UniProtKB=F7EI89	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000022303.3\|UniProtKB=A0A6I8NH99	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010004285.1\|UniProtKB=A0A8V0XGM3	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000010502.4\|UniProtKB=A0A803SVI2	Anolis carolinensis	LDO
XENLA\|Gene=LOC108705432\|UniProtKB=A0A8J1KNI7	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-953331\|UniProtKB=Q07G00	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000018460.2\|UniProtKB=H2MW77	Oryzias latipes	LDO
DANRE\|Gene=slc18b1\|UniProtKB=A0A8M2B5I6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000016237.1\|UniProtKB=W5NHB1	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000020876.1\|UniProtKB=H2XK52	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118419488\|UniProtKB=A0A9J7LF93	Branchiostoma floridae	O
BRAFL\|Gene=LOC118404724\|UniProtKB=A0A9J7KH72	Branchiostoma floridae	O
BRAFL\|Gene=LOC118418959\|UniProtKB=A0A9J7LDU9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118419489\|UniProtKB=A0A9J7MX41	Branchiostoma floridae	O
BRAFL\|Gene=LOC118407510\|UniProtKB=A0A9J7HQC4	Branchiostoma floridae	LDO
BRAFL\|Gene=LOC118419490\|UniProtKB=A0A9J7LHE1	Branchiostoma floridae	O
BRAFL\|Gene=LOC118418803\|UniProtKB=A0A9J7LD90	Branchiostoma floridae	O
BRAFL\|Gene=LOC118419027\|UniProtKB=A0A9J7LER2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118407511\|UniProtKB=A0A9J7HT39	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC105441943\|UniProtKB=A0A7M7NZ91	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100887893\|UniProtKB=A0A7M7N5B4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100891858\|UniProtKB=A0A7M7N299	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC584747\|UniProtKB=A0A7M7HFT1	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105437415\|UniProtKB=A0A7M7HIG1	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC594160\|UniProtKB=A0A7M7MZR6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100888927\|UniProtKB=A0A7M7SSR1	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00018860\|UniProtKB=H2KYF2	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG08069\|UniProtKB=A8X5Q6	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00109691\|UniProtKB=A0A2A6B5D3	Pristionchus pacificus	LDO
TRICA\|EnsemblGenome=TC033112\|UniProtKB=A0A139WH29	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC013544\|UniProtKB=D6WKY9	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_303768\|UniProtKB=E9GI10	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_332905\|UniProtKB=E9HR98	Daphnia pulex	O
ANOGA\|EnsemblGenome=AGAP001980\|UniProtKB=Q7PYK2	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC013893\|UniProtKB=D6WMQ6	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_315076\|UniProtKB=E9G8M8	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_319730\|UniProtKB=E9GMM8	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW015275\|UniProtKB=B7QMP4	Ixodes scapularis	LDO
IXOSC\|EnsemblGenome=ISCW022407\|UniProtKB=B7QA30	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW017160\|UniProtKB=B7P7T1	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW017158\|UniProtKB=B7P7S9	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW019583\|UniProtKB=B7PV74	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG91778\|UniProtKB=T1G887	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g213661\|UniProtKB=A7SKG0	Nematostella vectensis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g214544\|UniProtKB=A7SMH9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g171569\|UniProtKB=A7SKG1	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG58955\|UniProtKB=B3S451	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG58963\|UniProtKB=B3S459	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG51494\|UniProtKB=B3RJD0	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG58954\|UniProtKB=B3S450	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG58957\|UniProtKB=B3S453	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG64145\|UniProtKB=B3S458	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG58799\|UniProtKB=B3S3P7	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG58964\|UniProtKB=B3S460	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG58958\|UniProtKB=B3S454	Trichoplax adhaerens	LDO
TRIAD\|EnsemblGenome=TriadG51495\|UniProtKB=B3RJD1	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG60062\|UniProtKB=B3S769	Trichoplax adhaerens	O
PARTE\|EnsemblGenome=GSPATT00023132001\|UniProtKB=A0E3U2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00014105001\|UniProtKB=A0D7X1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028036001\|UniProtKB=A0BEN6	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00005685001\|UniProtKB=A0BV72	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00018142001\|UniProtKB=A0DLA8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00027749001\|UniProtKB=A0BDV2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00015710001\|UniProtKB=A0DCT4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00025815001\|UniProtKB=A0EDV4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00026238001\|UniProtKB=A0EF24	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028034001\|UniProtKB=A0BEN4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00032164001\|UniProtKB=A0BTR5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00000650001\|UniProtKB=A0CJH2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00026063001\|UniProtKB=A0EEK0	Paramecium tetraurelia	O
PHYRM\|Gene=H3GY18_PHYRM\|UniProtKB=H3GY18	Phytophthora ramorum	LDO
KLENI\|Gene_ORFName=KFL_001400230\|UniProtKB=A0A1Y1HX57	Klebsormidium nitens	LDO
KLENI\|Gene_ORFName=KFL_001410320\|UniProtKB=A0A0U9HJV2	Klebsormidium nitens	O
KORCO\|EnsemblGenome=Kcr_1033\|UniProtKB=B1L5Q0	Korarchaeum cryptofilum	O
PYRAE\|EnsemblGenome=PAE2306\|UniProtKB=Q8ZVF8	Pyrobaculum aerophilum	O
METJA\|EnsemblGenome=MJ_1560\|UniProtKB=Q58955	Methanocaldococcus jannaschii	O