PANTHER Gene Information   
Gene Symbol(s): Birc2
Organism: Rattus norvegicus
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Gene Name: Baculoviral IAP repeat-containing 2
Gene ID: 620690
Protein ID: Q6P6S1
Persistent Id: PTN000005360
Alternate Ids:
Q6P6S1_RAT(UniProtKB-ID) XP_006242556(refSeq)
ENSRNOG00000010602(Ensembl) 148747116(GI)
ENSRNOT00000014560(Ensembl_TRS) Q6P6S1(Synonym)
ENSRNOP00000014560(Ensembl_PRO) 620690(RGD)
60371(GeneID)
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PANTHER Classification
PANTHER Family: INHIBITOR OF APOPTOSIS (PTHR10044)
PANTHER Subfamily: BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 2 (PTHR10044:SF79)  
PANTHER GO-slim Molecular Function: enzyme regulator activity
ubiquitin protein ligase activity
PANTHER GO-slim Biological Process: positive regulation of protein modification process
regulation of cell cycle
negative regulation of apoptotic process
PANTHER GO-slim Cellular Component: nucleus
cytoplasm
PANTHER protein class: protease inhibitor
Pathway Categories: Apoptosis signaling pathway
   Cellular inhibitor of apoptosis protein 1 and 2
CCKR signaling map
   BIRC2
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: ubiquitin-protein transferase activity, zinc ion binding, identical protein binding, ubiquitin protein ligase activity, transcription coactivator activity, ubiquitin binding, protein-folding chaperone binding, transferase activity, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, FBXO family protein binding, protein-containing complex binding
GO BP Complete: regulation of non-canonical NF-kappaB signal transduction, positive regulation of canonical NF-kappaB signal transduction, response to cAMP, placenta development, regulation of necroptotic process, negative regulation of necroptotic process, response to ethanol, response to hypoxia, positive regulation of DNA-templated transcription, necroptotic process, apoptotic process, positive regulation of protein ubiquitination, regulation of reactive oxygen species metabolic process, cellular response to tumor necrosis factor, regulation of cell cycle, negative regulation of ripoptosome assembly involved in necroptotic process, protein polyubiquitination, positive regulation of protein K63-linked ubiquitination, positive regulation of protein K48-linked ubiquitination, regulation of apoptotic process, response to organic cyclic compound, positive regulation of protein monoubiquitination, positive regulation of protein polyubiquitination, proteasome-mediated ubiquitin-dependent protein catabolic process, negative regulation of apoptotic process
GO CC Complete: XY body, nucleus, cytoplasm, protein-containing complex, CD40 receptor complex, cytoplasmic side of plasma membrane
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Death Receptor Signaling, Apoptotic cleavage of cellular proteins, Deubiquitination, Apoptosis, Toll Like Receptor 4 (TLR4) Cascade, TNFR2 non-canonical NF-kB pathway, RIPK1-mediated regulated necrosis, Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, TNFR1-induced NF-kappa-B signaling pathway, TNF signaling, IKK complex recruitment mediated by RIP1, Innate Immune System, Apoptotic execution phase, Ub-specific processing proteases, TRIF(TICAM1)-mediated TLR4 signaling , Signal Transduction, MyD88-independent TLR4 cascade , Regulation of necroptotic cell death, Metabolism of proteins, TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway, Post-translational protein modification, Regulated Necrosis, Regulation of TNFR1 signaling, Immune System, Programmed Cell Death, Toll-like Receptor Cascades, TNFR1-induced proapoptotic signaling, NOD1/2 Signaling Pathway, Cytokine Signaling in Immune system

Orthologs