PANTHER Gene Information

Gene Symbol(s):

LDHAL6A

Organism:

Homo sapiens

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Gene Name:

L-lactate dehydrogenase A-like 6A

Gene ID:

HGNC:28335

Protein ID:

Q6ZMR3

Enhancers:

View enhancers for HUMAN|HGNC=28335|UniProtKB=Q6ZMR3

Genetic Variant Annotation:

Annoq

Persistent Id:

PTN002534610

Alternate Ids:

32693754(GI)	BAD18662(EMBL-CDS)
HGNC:28335(HGNC)	160287(GeneID)
618928(MIM)	ENSP00000379516(Ensembl_PRO)
LDHAL6A(Symbol)	LDHL2(Synonym)
AK131523(EMBL)	ENST00000280706(Ensembl_TRS)
LDH6A_HUMAN(UniProtKB-ID)	ENSG00000166800(Ensembl)
NM_001144071(refSeq)	D3DQY5(AltAccession)
1.1.1.27 {ECO:0000269\|PubMed:18351441}(EC)
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PANTHER Classification

PANTHER Family:	L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) (PTHR43128)
PANTHER Subfamily:	L-LACTATE DEHYDROGENASE A-LIKE 6A (PTHR43128:SF9)
PANTHER GO-slim Molecular Function:	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
PANTHER GO-slim Biological Process:	monocarboxylic acid metabolic process organic hydroxy compound metabolic process
PANTHER GO-slim Cellular Component:
PANTHER protein class:	dehydrogenase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	L-lactate dehydrogenase activity
GO BP Complete:	lactate metabolic process, pyruvate metabolic process
GO CC Complete:	extracellular exosome, cytoplasm, mitochondrion

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Metabolism, The citric acid (TCA) cycle and respiratory electron transport, Pyruvate metabolism and Citric Acid (TCA) cycle, Pyruvate metabolism

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000003423.6\|UniProtKB=A0A2J8P4T2	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000039584.1\|UniProtKB=A0A2I2Z7D8	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000014614.3\|UniProtKB=F7GNJ6	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2146830\|UniProtKB=Q8BVP2	Mus musculus	O
RAT\|RGD=727955\|UniProtKB=Q7TNA8	Rattus norvegicus	O
BOVIN\|Gene=LDHAL6B\|UniProtKB=Q3T056	Bos taurus	O
HORSE\|Ensembl=ENSECAG00000056473.1\|UniProtKB=A0A9L0SXS2	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000011596.4\|UniProtKB=A0A3Q2HI68	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000049116.1\|UniProtKB=A0A5F5Y149	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845000800.1\|UniProtKB=A0A8I3MH49	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000019596.3\|UniProtKB=A0A5S8BEX8	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000006509.3\|UniProtKB=F7EJX3	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000016773.3\|UniProtKB=F7GGA7	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000040672.1\|UniProtKB=A0A5F8GE81	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000023086.2\|UniProtKB=F7BNV4	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000006522\|UniProtKB=Q9XT87	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000008367.4\|UniProtKB=F7BRJ4	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000048733.1\|UniProtKB=A0A6I8PC18	Ornithorhynchus anatinus	O
CHICK\|Gene=LDHA\|UniProtKB=P00340	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010024472.1\|UniProtKB=E1BTT8	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000000061.4\|UniProtKB=G1K888	Anolis carolinensis	O
XENLA\|Gene=ldha.L\|UniProtKB=Q9W7M7	Xenopus laevis	O
XENLA\|Gene=ldha.S\|UniProtKB=Q9W5Z7	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-480608\|UniProtKB=Q6P7L5	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000003767.2\|UniProtKB=A0A3B3I1R7	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-991026-5\|UniProtKB=Q9PVK5	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000000737.1\|UniProtKB=W5LXG1	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000003426.3\|UniProtKB=F6XLK3	Ciona intestinalis	O
STRPU\|EnsemblGenome=LOC115917976\|UniProtKB=A0A7M7NZ80	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC586683\|UniProtKB=A0A7M7P3V3	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00002262\|UniProtKB=Q27888	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG03136\|UniProtKB=A8WSQ2	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00304582\|UniProtKB=A0A8R1Z903	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0033856\|UniProtKB=A1Z9F8	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0001258\|UniProtKB=Q95028	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP004880\|UniProtKB=Q7Q981	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC003922\|UniProtKB=D6WHN0	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_61140\|UniProtKB=E9HCE3	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_230172\|UniProtKB=E9FTK7	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG156879\|UniProtKB=T1EM25	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG166102\|UniProtKB=T1EXR7	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG115469\|UniProtKB=T1EG84	helobdella robusta	O
MONBE\|EnsemblGenome=MONBRDRAFT_32392\|UniProtKB=A9UZ89	Monosiga brevicollis	O
AMBTC\|EnsemblGenome=AMTR_s00007p00083810\|UniProtKB=W1P5V6	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_85G00700\|UniProtKB=A0A0K9NLK7	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_26G01440\|UniProtKB=A0A0K9PEA0	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_85G00680\|UniProtKB=A0A0K9NL55	Zostera marina	O
MUSAM\|EnsemblGenome=Ma01_g13550\|UniProtKB=A0A804HTP8	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma07_g06750\|UniProtKB=A0A804JSZ9	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma07_g06760\|UniProtKB=A0A804JT00	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_019533mg\|UniProtKB=K3YZ26	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3004G004500\|UniProtKB=C5XRJ7	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb229440\|UniProtKB=A0A804U7B0	Zea mays	O
SETIT\|EnsemblGenome=SETIT_017639mg\|UniProtKB=K3YTP3	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3004G004400\|UniProtKB=C5XRJ6	Sorghum bicolor	O
MAIZE\|Gene=LDH_MAIZE\|UniProtKB=P29038	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb229430\|UniProtKB=B6T856	Zea mays	O
ORYSJ\|EnsemblGenome=Os06g0104900\|UniProtKB=Q9LWZ6	Oryza sativa	O
ORYSJ\|EnsemblGenome=Os02g0105400\|UniProtKB=Q0E4Q5	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_3g15560v3\|UniProtKB=I1I144	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0107000\|UniProtKB=A0A8I6WQS5	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS7B02G317500\|UniProtKB=A0A3B6SK62	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7B02G317900\|UniProtKB=A0A3B6SHI3	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2B02G091400\|UniProtKB=A0A3B6BZD0	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7A02G417800\|UniProtKB=A0A3B6RP30	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7D02G410800\|UniProtKB=A0A3B6TVM4	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2D02G075200\|UniProtKB=A0A3B6D9F6	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7A02G417400\|UniProtKB=A0A3B6RNX9	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6B02G029700\|UniProtKB=A0A3B6PDH3	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2A02G076600\|UniProtKB=A0A3B6ASL4	Triticum aestivum	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0552610\|UniProtKB=A0A8I7BB49	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS6B02G116700\|UniProtKB=A0A3B6PIW3	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6D02G078300\|UniProtKB=A0A3B6QD94	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6A02G085300\|UniProtKB=A0A3B6NJD4	Triticum aestivum	O
NELNU\|Gene_ORFName=HUJ06_017754\|UniProtKB=A0A1U8AAA6	Nelumbo nucifera	O
NELNU\|Gene=LOC104598555\|UniProtKB=A0A1U7ZYQ4	Nelumbo nucifera	O
SPIOL\|Gene=LOC110792497\|UniProtKB=A0A9R0IP55	Spinacia oleracea	O
HELAN\|Gene_ORFName=HanXRQr2_Chr02g0073481\|UniProtKB=A0A9K3JNW6	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr13g0578121\|UniProtKB=A0A251SQ98	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C600299770\|UniProtKB=A0A9R1X7M9	Lactuca sativa	O
HELAN\|Gene_ORFName=HanXRQr2_Chr17g0800981\|UniProtKB=A0A9K3GU27	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr17g0801001\|UniProtKB=A0A9K3GUH5	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr06g0238801\|UniProtKB=A0A251UEK1	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C300101670\|UniProtKB=A0A9R1W2L3	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a009187mg\|UniProtKB=A0A022QZV6	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_03876\|UniProtKB=A0A2G3AP36	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400012478\|UniProtKB=M1AXH9	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc08g007420.3\|UniProtKB=A0A3Q7HKP3	Solanum lycopersicum	O
TOBAC\|Gene=LOC107806030\|UniProtKB=A0A077D9R7	Nicotiana tabacum	O
CAPAN\|EnsemblGenome=T459_00568\|UniProtKB=A0A2G3AEL6	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400004800\|UniProtKB=M1A0Y3	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc08g078850.3\|UniProtKB=Q96569	Solanum lycopersicum	O
TOBAC\|Gene=LOC107780728\|UniProtKB=A0A1S3YWT9	Nicotiana tabacum	O
TOBAC\|Gene=LOC107803141\|UniProtKB=A0A1S4AZZ0	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi15g00715\|UniProtKB=F6I382	Vitis vinifera	O
VITVI\|EnsemblGenome=Vitvi02g00533\|UniProtKB=D7TN36	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_D02046\|UniProtKB=A0A059CH86	Eucalyptus grandis	O
EUCGR\|EnsemblGenome=EUGRSUZ_E00444\|UniProtKB=A0A059C263	Eucalyptus grandis	O
BRANA\|Gene_ORFName=DARMORV10_C01P25250.1\|UniProtKB=A0A078HD00	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A01P20100.1\|UniProtKB=A0A078I074	Brassica napus	O
BRACM\|EnsemblGenome=Bra026240\|UniProtKB=A0A3P5Z6C3	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00031281001\|UniProtKB=A0A078F8I0	Brassica napus	O
BRACM\|EnsemblGenome=Bra012671\|UniProtKB=A0A398AAN2	Brassica campestris	O
ARATH\|TAIR=locus=2130764\|UniProtKB=O23569	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107940833\|UniProtKB=A0A1U8MW28	Gossypium hirsutum	O
GOSHI\|Gene=LOC107946940\|UniProtKB=A0A1U8NGK4	Gossypium hirsutum	O
GOSHI\|Gene=LOC107942082\|UniProtKB=A0A1U8N066	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_015995\|UniProtKB=A0A061GBE3	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g018760mg\|UniProtKB=A0A067F5R0	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_003G111200v3\|UniProtKB=U5GJ57	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_001G122400v3\|UniProtKB=U5GU43	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_02G038200\|UniProtKB=A0A2C9WAN2	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_01G079100\|UniProtKB=A0A2C9WIP3	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0540800\|UniProtKB=B9SIT4	Ricinus communis	O
RICCO\|Gene_ORFName=RCOM_0540790\|UniProtKB=B9SIT3	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_17G140600\|UniProtKB=I1MUZ7	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_05G058100\|UniProtKB=A0A0R0JRB0	Glycine max	O
MEDTR\|EnsemblGenome=MTR_4g101130\|UniProtKB=G7JIY5	Medicago truncatula	O
SOYBN\|EnsemblGenome=GLYMA_01G210400\|UniProtKB=I1J9W9	Glycine max	O
MEDTR\|EnsemblGenome=MTR_5g012390\|UniProtKB=G7JW16	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr02_20010\|UniProtKB=A0A2I4GWV6	Juglans regia	O
JUGRE\|Gene=LOC109013131\|UniProtKB=A0A6P9ER86	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_5G161920\|UniProtKB=A0A0A0KKU9	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_5G072700\|UniProtKB=M5X008	Prunus persica	O
PRUPE\|EnsemblGenome=PRUPE_1G339800\|UniProtKB=M5Y9S9	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_236713\|UniProtKB=D8TCK2	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_92401\|UniProtKB=D8RFP2	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_405919\|UniProtKB=D8R035	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_447483\|UniProtKB=D8SZU9	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c21_11360\|UniProtKB=A9TI55	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c18_10120\|UniProtKB=A0A2K1J0K3	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c22_12920\|UniProtKB=A0A2K1INA9	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0049s0082\|UniProtKB=A0A2R6WY69	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_001690070\|UniProtKB=A0A1Y1I3E4	Klebsormidium nitens	O