PANTHER Gene Information

Gene Symbol(s):

HPS1

Organism:

Drosophila melanogaster

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Gene Name:

GH27401p

Gene ID:

FBgn0033973

Protein ID:

Q7K3N1

Persistent Id:

PTN000298638

Alternate Ids:

Q7K3N1(Synonym)	FBpp0086579(Ensembl_PRO)
AAF58194(EMBL-CDS)	AE013599(EMBL)
7303129(GI)	FBgn0033973(Ensembl)
Q7K3N1_DROME(UniProtKB-ID)	NP_610997(refSeq)
FBgn0033973(FlyBase)	36656(GeneID)
FBtr0087449(Ensembl_TRS)
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PANTHER Classification

PANTHER Family:	HERMANSKY-PUDLAK SYNDROME PROTEIN 1 (PTHR12761)
PANTHER Subfamily:	BLOC-3 COMPLEX MEMBER HPS1 (PTHR12761:SF1)
PANTHER GO-slim Molecular Function:	guanyl-nucleotide exchange factor activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	intracellular protein-containing complex
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	guanyl-nucleotide exchange factor activity
GO BP Complete:	vesicle-mediated transport
GO CC Complete:	BLOC-3 complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Rab regulation of trafficking, RAB GEFs exchange GTP for GDP on RABs, Membrane Trafficking, Vesicle-mediated transport

Orthologs

ID	Organism	Type
HUMAN\|HGNC=5163\|UniProtKB=Q92902	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000002825.7\|UniProtKB=H2QZM8	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000002508.3\|UniProtKB=G3QJ89	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000020604.4\|UniProtKB=F7BZ61	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2177763\|UniProtKB=O08983	Mus musculus	LDO
RAT\|RGD=69193\|UniProtKB=A0A8I6AEI1	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000014314.6\|UniProtKB=E1B7M9	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000010534.5\|UniProtKB=A0A287BFN6	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000000393.4\|UniProtKB=F6WUZ3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000009348.6\|UniProtKB=M3WB95	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845030620.1\|UniProtKB=A0A8I3Q440	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000003664.4\|UniProtKB=F7ACC0	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000003472.5\|UniProtKB=F6VEG8	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010018374.1\|UniProtKB=A0A8V0ZD08	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000002534.4\|UniProtKB=G1KAU2	Anolis carolinensis	LDO
XENLA\|Gene=hps1.S\|UniProtKB=A0A8J0TET7	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-977903\|UniProtKB=Q6DJS6	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000007785.2\|UniProtKB=H2LUH3	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-051113-152\|UniProtKB=Q32PM6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000009087.1\|UniProtKB=W5MRS6	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118414440\|UniProtKB=A0A9J7L2C7	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC100892007\|UniProtKB=A0A7M7NW04	Strongylocentrotus purpuratus	LDO
ANOGA\|EnsemblGenome=AGAP011210\|UniProtKB=A0A1S4H629	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC001237\|UniProtKB=D6WAY1	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_323149\|UniProtKB=E9GY17	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW003346\|UniProtKB=B7PBJ4	Ixodes scapularis	LDO
TRIAD\|EnsemblGenome=TriadG58519\|UniProtKB=B3S2X5	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_7282\|UniProtKB=A9UWH4	Monosiga brevicollis	LDO
DICDI\|dictyBase=DDB_G0286137\|UniProtKB=Q54M79	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_47448\|UniProtKB=F0ZJK6	Dictyostelium purpureum	LDO
TRIV3\|Gene_ORFName=TVAG_497160\|UniProtKB=A2EGV9	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_032520\|UniProtKB=A2FIT2	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_261960\|UniProtKB=A2DUA8	Trichomonas vaginalis	LDO
TRIV3\|Gene_ORFName=TVAG_123970\|UniProtKB=A2EMY8	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_010590\|UniProtKB=A2DNY6	Trichomonas vaginalis	O