PANTHER Gene Information   
Gene Symbol(s): EXOSC4
Organism: Bos taurus
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Gene Name: Exosome complex component RRP41
Gene ID: ENSBTAG00000014607
Protein ID: Q7YRA3
Persistent Id: PTN000237461
Alternate Ids:
EXOS4(Synonym) EXOSC4(Symbol)
AJ518955(EMBL) ENSBTAT00000019451(Ensembl_TRS)
ENSBTAG00000014607(Ensembl) AAI09820(EMBL-CDS)
NP_001071554(refSeq) 75045923(GI)
EXOS4_BOVIN(UniProtKB-ID) Q32L11(AltAccession)
618292(GeneID) ENSBTAP00000019451(Ensembl_PRO)
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PANTHER Classification
PANTHER Family: EXOSOME COMPLEX COMPONENT (PTHR11953)
PANTHER Subfamily: EXOSOME COMPLEX COMPONENT RRP41 (PTHR11953:SF0)  
PANTHER GO-slim Molecular Function: RNA binding
PANTHER GO-slim Biological Process: rRNA metabolic process
RNA catabolic process
PANTHER GO-slim Cellular Component:
PANTHER protein class: exoribonuclease
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: RNA binding, mRNA 3'-UTR AU-rich region binding, exonuclease activity
GO BP Complete: positive regulation of cell growth, poly(A)-dependent snoRNA 3'-end processing, maturation of 5.8S rRNA, U4 snRNA 3'-end processing, histone mRNA catabolic process, rRNA catabolic process, nuclear mRNA surveillance, DNA deamination, defense response to virus
GO CC Complete: cytoplasmic exosome (RNase complex), nuclear exosome (RNase complex), euchromatin, cytosol, nucleolus, exosome (RNase complex), nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: mRNA decay by 3' to 5' exoribonuclease, Deadenylation-dependent mRNA decay, Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA, KSRP (KHSRP) binds and destabilizes mRNA, Metabolism of RNA, Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA, Regulation of mRNA stability by proteins that bind AU-rich elements, rRNA processing in the nucleus and cytosol, Major pathway of rRNA processing in the nucleolus and cytosol, rRNA processing

Orthologs