PANTHER Gene Information

Gene Symbol(s):

wdr24

Organism:

Danio rerio

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Gene Name:

GATOR complex protein WDR24

Gene ID:

ZDB-GENE-040426-2012

Protein ID:

Q7ZVL2

Persistent Id:

PTN000522766

Alternate Ids:

wdr24{ECO:0000250\|UniProtKB:Q96S15}(Symbol)	406336(GeneID)
BC045501(EMBL)	WDR24(Synonym)
82241414(GI)	AAH45501(EMBL-CDS)
NP_998228(refSeq)	2.3.2.27 {ECO:0000250\|UniProtKB:Q96S15}(EC)
ZDB-GENE-040426-2012(ZFIN)	WDR24_DANRE(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	GATOR COMPLEX PROTEIN WDR24 (PTHR46200)
PANTHER Subfamily:	GATOR COMPLEX PROTEIN WDR24 (PTHR46200:SF1)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	positive regulation of TORC1 signaling positive regulation of macroautophagy
PANTHER GO-slim Cellular Component:	cytosol vacuolar membrane Seh1-associated complex
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ubiquitin protein ligase activity, metal ion binding, transferase activity
GO BP Complete:	positive regulation of macroautophagy, positive regulation of TORC1 signaling, cellular response to nutrient levels, autophagy, cellular response to amino acid starvation, positive regulation of TOR signaling, protein K6-linked ubiquitination
GO CC Complete:	membrane, cytosol, vacuolar membrane, lysosomal membrane, GATOR2 complex, lysosome

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=20852\|UniProtKB=Q96S15	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000007554.5\|UniProtKB=K7DT44	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000013868.3\|UniProtKB=A0A2I2YVQ2	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000001986.4\|UniProtKB=A0A1D5REC0	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2446285\|UniProtKB=Q8CFJ9	Mus musculus	LDO
RAT\|RGD=1304803\|UniProtKB=G3V8L0	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000019006.4\|UniProtKB=F1MJS7	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000008007.5\|UniProtKB=F1RG37	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000012781.4\|UniProtKB=F6QL31	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000008313.5\|UniProtKB=A0A2I2UZB6	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845026744.1\|UniProtKB=A0A8I3PTX8	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000016752.4\|UniProtKB=F6YL80	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000040783.1\|UniProtKB=A0A6I8P4B7	Ornithorhynchus anatinus	LDO
CHICK\|Gene_ORFName=RCJMB04_1a19\|UniProtKB=Q5ZMV9	Gallus gallus	LDO
CHICK\|Ensembl=ENSGALG00010018345.1\|UniProtKB=A0A3Q2U8E6	Gallus gallus	LDO
XENLA\|Gene=wdr24.L\|UniProtKB=A0A8J1LQC5	Xenopus laevis	LDO
XENLA\|Gene=wdr24\|UniProtKB=Q7ZX22	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5898584\|UniProtKB=B4F6T9	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000007670.2\|UniProtKB=H2LU36	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000003515.1\|UniProtKB=W5M701	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000007708.3\|UniProtKB=F6WK69	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118429291\|UniProtKB=A0A9J7MAJ8	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC589654\|UniProtKB=A0A7M7P3Z8	Strongylocentrotus purpuratus	LDO
DROME\|FlyBase=FBgn0027518\|UniProtKB=Q9XZ25	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP001159\|UniProtKB=Q7PX12	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC012809\|UniProtKB=D6X0T6	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_52862\|UniProtKB=E9GN97	Daphnia pulex	LDO
TRIAD\|EnsemblGenome=TriadG54980\|UniProtKB=B3RQG5	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_34454\|UniProtKB=A9VBV5	Monosiga brevicollis	LDO
YEAST\|SGD=S000005498\|UniProtKB=Q08281	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_ADL186C\|UniProtKB=Q75AV6	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000194538\|UniProtKB=Q5ACL4	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_B17842g\|UniProtKB=Q6CE79	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_04518\|UniProtKB=Q5B4L2	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_2G03080\|UniProtKB=Q4WI50	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU08632\|UniProtKB=Q7SFI9	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_06034\|UniProtKB=A7EL37	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_00513\|UniProtKB=Q0V651	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC4F8.11\|UniProtKB=O14186	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_04496\|UniProtKB=B6K6Z5	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNI01700\|UniProtKB=Q5KBR1	Cryptococcus neoformans	LDO
PUCGT\|EnsemblGenome=PGTG_07183\|UniProtKB=E3K9Q7	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_28089\|UniProtKB=F4PCT2	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0287817\|UniProtKB=Q54JS5	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_55360\|UniProtKB=F0ZLR7	Dictyostelium purpureum	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_20675\|UniProtKB=B8BQ09	Thalassiosira pseudonana	LDO