PANTHER Gene Information   
Gene Symbol(s): creb1
Organism: Danio rerio
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Gene Name: Creb1 protein
Gene ID: ZDB-GENE-040426-750
Protein ID: Q803K8
Persistent Id: PTN005257752
Alternate Ids:
573207(GeneID) ZDB-GENE-040426-750(ZFIN)
BC044436(EMBL) NM_200909(refSeq)
ENSDARG00000053586(Ensembl) Q803K8_DANRE(UniProtKB-ID)
ENSDARP00000070114(Ensembl_PRO) AAI64114(EMBL-CDS)
Q803K8(Synonym) ENSDART00000187346(Ensembl_TRS)
82210129(GI)
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PANTHER Classification
PANTHER Family: CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN B (PTHR45879)
PANTHER Subfamily: CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 1 (PTHR45879:SF1)  
PANTHER GO-slim Molecular Function: DNA-binding transcription factor activity, RNA polymerase II-specific
RNA polymerase II cis-regulatory region sequence-specific DNA binding
PANTHER GO-slim Biological Process: regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component: RNA polymerase II transcription regulator complex
PANTHER protein class: basic leucine zipper transcription factor
Pathway Categories: Transcription regulation by bZIP transcription factor
   cAMP response element binding protein
Enkephalin release
   cAMP response element binding protein
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
   CREB binding protein
Gonadotropin-releasing hormone receptor pathway
   CREB
p38 MAPK pathway
   cAMP response element binding protein
CCKR signaling map
   CREB1
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
   cAMP response element binding protein
Apoptosis signaling pathway
   Activating transcription factor

GO MF Complete: DNA binding, DNA-binding transcription factor activity, cAMP response element binding, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete: somitogenesis, regulation of DNA-templated transcription, midbrain-hindbrain boundary development, convergent extension involved in axis elongation, regulation of transcription by RNA polymerase II
GO CC Complete: nucleus, ATF4-CREB1 transcription factor complex
Reactome Pathways: MAPK targets/ Nuclear events mediated by MAP kinases, TRIF(TICAM1)-mediated TLR4 signaling , Cytokine Signaling in Immune system, Estrogen-dependent nuclear events downstream of ESR-membrane signaling, TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation, Intracellular signaling by second messengers, NGF-stimulated transcription, Interleukin-17 signaling, Signal Transduction, Toll Like Receptor 5 (TLR5) Cascade, MyD88:MAL(TIRAP) cascade initiated on plasma membrane, Immune System, Toll Like Receptor TLR1:TLR2 Cascade, Toll Like Receptor 4 (TLR4) Cascade, Toll Like Receptor 9 (TLR9) Cascade, Toll-like Receptor Cascades, Nuclear Events (kinase and transcription factor activation), MyD88 cascade initiated on plasma membrane, Toll Like Receptor 2 (TLR2) Cascade, MyD88 dependent cascade initiated on endosome, PIP3 activates AKT signaling, Signaling by Nuclear Receptors, MAP kinase activation, Signaling by Receptor Tyrosine Kinases, Signaling by NTRK1 (TRKA), Signaling by Interleukins, Toll Like Receptor 7/8 (TLR7/8) Cascade, Toll Like Receptor TLR6:TLR2 Cascade, Toll Like Receptor 3 (TLR3) Cascade, Toll Like Receptor 10 (TLR10) Cascade, MyD88-independent TLR4 cascade , Signaling by NTRKs, ESR-mediated signaling, Extra-nuclear estrogen signaling, Innate Immune System, CREB phosphorylation, AKT phosphorylates targets in the nucleus