PANTHER Gene Information

Gene Symbol(s):

Kcmf1

Organism:

Mus musculus

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Gene Name:

E3 ubiquitin-protein ligase KCMF1

Gene ID:

MGI:1921537

Protein ID:

Q80UY2

Persistent Id:

PTN000263024

Alternate Ids:

27695908(GI)	BC043330(EMBL)
Debt91(Synonym)	Kcmf1(Symbol)
AAD31040(EMBL-CDS)	74287(GeneID)
KCMF1_MOUSE(UniProtKB-ID)	Q9WUM2(AltAccession)
2.3.2.27(EC)	MGI:1921537(MGI)
ENSMUSG00000055239(Ensembl)
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PANTHER Classification

PANTHER Family:	E3 UBIQUITIN-PROTEIN LIGASE KCMF1 (PTHR12268)
PANTHER Subfamily:	E3 UBIQUITIN-PROTEIN LIGASE KCMF1 (PTHR12268:SF13)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	synaptic signaling
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	ubiquitin-protein ligase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	zinc ion binding, ubiquitin protein ligase activity
GO BP Complete:	response to oxidative stress, proteasome-mediated ubiquitin-dependent protein catabolic process, protein K48-linked ubiquitination, synaptic signaling, negative regulation of HRI-mediated signaling, protein K63-linked ubiquitination, protein ubiquitination
GO CC Complete:	cytoplasm, late endosome, cytosol, plasma membrane, lysosome

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Immune System, Innate Immune System, Neutrophil degranulation

Orthologs

ID	Organism	Type
HUMAN\|HGNC=20589\|UniProtKB=Q9P0J7	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000012127.6\|UniProtKB=K7CHG2	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000009501.3\|UniProtKB=G3R243	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000001414.4\|UniProtKB=H9FXB2	Macaca mulatta	LDO
RAT\|RGD=1591490\|UniProtKB=B2RZ97	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000020630.6\|UniProtKB=F1MWM6	Bos taurus	O
BOVIN\|Gene=KCMF1\|UniProtKB=Q1LZE1	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000008242.5\|UniProtKB=A0A5G2Q6P4	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000024834.4\|UniProtKB=F6QXC5	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000044295.2\|UniProtKB=A0A337SPV8	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845014677.1\|UniProtKB=A0A8I3NUD9	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000015567.4\|UniProtKB=F6RF07	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000007129.4\|UniProtKB=A0A6I8NQQ0	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010012888.1\|UniProtKB=A0A1D5NWN1	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010012060.1\|UniProtKB=A0A8V0YDR9	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000005906.4\|UniProtKB=H9GAQ4	Anolis carolinensis	LDO
XENLA\|Gene=kcmf1.L\|UniProtKB=A0A8J1M383	Xenopus laevis	O
XENLA\|Gene=LOC108706815\|UniProtKB=A0A8J0U8T2	Xenopus laevis	O
XENLA\|Gene=kcmf1\|UniProtKB=Q6GPB6	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1021676\|UniProtKB=B1H326	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000001840.2\|UniProtKB=A0A3B3I8C2	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-1383\|UniProtKB=Q7T321	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000011313.1\|UniProtKB=W5MZU2	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000005635.3\|UniProtKB=H2XTC5	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118412988\|UniProtKB=A0A9J7MLZ0	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC575958\|UniProtKB=A0A7M7HIC8	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00022785\|UniProtKB=P34664	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00033219\|UniProtKB=A8XF27	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00107380\|UniProtKB=A0A8R1UE34	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0015926\|UniProtKB=Q24175	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP000996\|UniProtKB=A0A1S4GAP1	Anopheles gambiae	O
DROME\|FlyBase=FBgn0028531\|UniProtKB=Q9VJT3	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0051642\|UniProtKB=Q8IPJ9	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0037655\|UniProtKB=Q95RX5	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP002670\|UniProtKB=A0A1S4GFL1	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC004633\|UniProtKB=D6W7D8	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_310981\|UniProtKB=E9FW83	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW022121\|UniProtKB=B7QDE6	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g189692\|UniProtKB=A7SGR5	Nematostella vectensis	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_22129\|UniProtKB=A9UPN1	Monosiga brevicollis	O
EREGS\|EnsemblGenome=AGOS_AER029C\|UniProtKB=Q757I4	Eremothecium gossypii	O
CANAL\|CGD=CAL0000180532\|UniProtKB=A0A1D8PJ35	Candida albicans	O
PARTE\|EnsemblGenome=GSPATT00003817001\|UniProtKB=A0E6N5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00000529001\|UniProtKB=Q6BGJ3	Paramecium tetraurelia	O