PANTHER Gene Information

Gene Symbol(s):

Slc46a2

Organism:

Mus musculus

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Gene Name:

Thymic stromal cotransporter protein

Gene ID:

MGI:1353616

Protein ID:

Q8CA03

Persistent Id:

PTN000548194

Alternate Ids:

30936(GeneID)	12856565(GI)
TSCOT(Synonym)	ENSMUSP00000030081(Ensembl_PRO)
ENSMUST00000030081(Ensembl_TRS)	Slc46a2{ECO:0000303\|PubMed:34235268}(Symbol)
AAK28344(EMBL-CDS)	AF148145(EMBL)
NP_066395(refSeq)	ENSMUSG00000028386(Ensembl)
TSCOT_MOUSE(UniProtKB-ID)	Q9JLQ3(AltAccession)
MGI:1353616(MGI)
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PANTHER Classification

PANTHER Family:	ZGC:174356 (PTHR23507)
PANTHER Subfamily:	THYMIC STROMAL COTRANSPORTER HOMOLOG (PTHR23507:SF3)
PANTHER GO-slim Molecular Function:	transmembrane transporter activity
PANTHER GO-slim Biological Process:	transmembrane transport
PANTHER GO-slim Cellular Component:	membrane
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	cyclic-GMP-AMP transmembrane transporter activity, transmembrane transporter activity
GO BP Complete:	regulation of T cell differentiation, transmembrane transport, cyclic-GMP-AMP transmembrane import across plasma membrane, positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway, negative regulation of T cell apoptotic process, T cell homeostasis, thymus development
GO CC Complete:	membrane, endosome membrane, plasma membrane, cell surface

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=16055\|UniProtKB=Q9BY10	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000021268.4\|UniProtKB=H2QXP8	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000004221.3\|UniProtKB=G3QNM0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000000568.4\|UniProtKB=H9H2P4	Macaca mulatta	LDO
RAT\|RGD=1310485\|UniProtKB=D4A6S9	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000013670.5\|UniProtKB=Q58D30	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000005472.5\|UniProtKB=A0A5G2QHQ5	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000018603.4\|UniProtKB=A0A3Q2KS56	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000029049.4\|UniProtKB=A0A5F5XK74	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00030024680\|UniProtKB=Q866G7	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000004815.4\|UniProtKB=F6V5F1	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000000847.4\|UniProtKB=F6YJB3	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010007010.1\|UniProtKB=R4GFI6	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000017402.4\|UniProtKB=A0A803SS23	Anolis carolinensis	LDO
XENLA\|Gene=LOC108713384\|UniProtKB=A0A1L8HX69	Xenopus laevis	LDO
XENTR\|Ensembl=ENSXETG00000035525\|UniProtKB=A0A6I8QIX2	Xenopus tropicalis	LDO
XENLA\|Gene=LOC108713383\|UniProtKB=A0A8J0USL1	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000035801\|UniProtKB=A0A6I8S4K8	Xenopus tropicalis	O
XENLA\|Gene=slc46a2.L\|UniProtKB=A0A1L8HXK4	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-988711\|UniProtKB=A0A6I8QKY0	Xenopus tropicalis	O
DANRE\|Gene=si=ch211-262i1.4\|UniProtKB=A0A8M9Q0G8	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000001737.1\|UniProtKB=W5M0U9	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000011613.2\|UniProtKB=H2M7V0	Oryzias latipes	LDO
DANRE\|Gene=LOC100002406\|UniProtKB=A0A8M6Z1C1	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000002855.1\|UniProtKB=W5M4P6	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000000951.3\|UniProtKB=A0A1W5BNF9	Ciona intestinalis	O
BRAFL\|Gene=LOC118430014\|UniProtKB=A0A9J7N9Z4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118418484\|UniProtKB=A0A9J7LCE5	Branchiostoma floridae	O
BRAFL\|Gene=LOC118430983\|UniProtKB=A0A9J7MBK9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118409313\|UniProtKB=A0A9J7HUI5	Branchiostoma floridae	O
BRAFL\|Gene=LOC118431111\|UniProtKB=A0A9J7MC08	Branchiostoma floridae	O
BRAFL\|Gene=LOC118429249\|UniProtKB=A0A9J7M6P4	Branchiostoma floridae	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_67379\|UniProtKB=C3XQ25	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC581591\|UniProtKB=A0A7M7RGU0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC581639\|UniProtKB=A0A7M7TGJ8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC754028\|UniProtKB=A0A7M7N1R9	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC753373\|UniProtKB=A0A7M7HIS1	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00016705\|UniProtKB=H2KZC0	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00034978\|UniProtKB=A8XK32	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00089749\|UniProtKB=A0A2A6BFJ0	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00099347\|UniProtKB=A0A2A6CUT5	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00012811\|UniProtKB=Q9XWL3	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00027124\|UniProtKB=A8WXM0	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00116171\|UniProtKB=A0A2A6C634	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00009582\|UniProtKB=Q20236	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00038594\|UniProtKB=A8XVF6	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00102163\|UniProtKB=A0A2A6CRJ7	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00021159\|UniProtKB=Q9UAZ6	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00039085\|UniProtKB=A8XWU5	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00106714\|UniProtKB=A0A2A6CBQ4	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0260388\|UniProtKB=Q0E8E1	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP003000\|UniProtKB=A0A1S4GH99	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC006261\|UniProtKB=D6WVQ3	Tribolium castaneum	O
DROME\|FlyBase=FBgn0039817\|UniProtKB=Q9VA14	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0033387\|UniProtKB=B7YZU3	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0050345\|UniProtKB=Q1EC10	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0033388\|UniProtKB=A1Z7R6	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0050344\|UniProtKB=Q961H2	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP005319\|UniProtKB=Q7PNX3	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP005318\|UniProtKB=A0A1S4GNW5	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP005317\|UniProtKB=Q7Q7G7	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC033792\|UniProtKB=A0A139WEK6	Tribolium castaneum	O
DROME\|FlyBase=FBgn0051321\|UniProtKB=Q8INF8	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0030576\|UniProtKB=Q9VY22	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP009684\|UniProtKB=Q7Q1Q1	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP004562\|UniProtKB=Q5TSW5	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC033817\|UniProtKB=A0A139WEI0	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC008783\|UniProtKB=D6WRR1	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC008800\|UniProtKB=D6WRL5	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC015466\|UniProtKB=D2A535	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_329228\|UniProtKB=E9HG06	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_105878\|UniProtKB=E9GS40	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_247259\|UniProtKB=E9GS37	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_329199\|UniProtKB=E9HFY2	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_329198\|UniProtKB=E9HFY1	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_328004\|UniProtKB=E9HCE6	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW003974\|UniProtKB=B7PFJ1	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW001118\|UniProtKB=B7P6W2	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW005482\|UniProtKB=B7PM66	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW016652\|UniProtKB=B7P8P0	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG160835\|UniProtKB=T1EQS9	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG177365\|UniProtKB=T1FBK4	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG188191\|UniProtKB=T1FPR5	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG175544\|UniProtKB=T1F9D3	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g243729\|UniProtKB=A7S9D8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g197737\|UniProtKB=A7RIS8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g131488\|UniProtKB=A7STS4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g170737\|UniProtKB=A7SHN9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g238374\|UniProtKB=A7RHU0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g11092\|UniProtKB=A7SBG4	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g147317\|UniProtKB=A7T5Z8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g99988\|UniProtKB=A7S0P7	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g150599\|UniProtKB=A7T8V4	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG58349\|UniProtKB=B3S1V2	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG58348\|UniProtKB=B3S1V1	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG53884\|UniProtKB=B3RMB1	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_29622\|UniProtKB=A9VBM8	Monosiga brevicollis	O
NEUCR\|EnsemblGenome=NCU08748\|UniProtKB=Q7SCE7	Neurospora crassa	O
PHANO\|EnsemblGenome=SNOG_05561\|UniProtKB=Q0URQ3	Phaeosphaeria nodorum	O
CRYNJ\|EnsemblGenome=CNJ00360\|UniProtKB=Q5KAV2	Cryptococcus neoformans	O
YEAST\|SGD=S000003699\|UniProtKB=P46996	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AEL114C\|UniProtKB=Q757X6	Eremothecium gossypii	O
CANAL\|CGD=CAL0000179271\|UniProtKB=A0A1D8PK68	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_D24772g\|UniProtKB=Q6C7W7	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_D15026g\|UniProtKB=Q6C920	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_B06347g\|UniProtKB=Q6CFJ8	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_C04796g\|UniProtKB=Q6CD09	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_06344\|UniProtKB=Q5AZD6	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_8G06410\|UniProtKB=Q4WBY0	Neosartorya fumigata	O
ASPFU\|EnsemblGenome=AFUA_2G14230\|UniProtKB=Q4X097	Neosartorya fumigata	O
EMENI\|EnsemblGenome=ANIA_11031\|UniProtKB=C8V3Y8	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_8G02460\|UniProtKB=Q4WBJ0	Neosartorya fumigata	O
ASPFU\|EnsemblGenome=AFUA_5G12740\|UniProtKB=Q4WVN5	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU17155\|UniProtKB=V5IKB3	Neurospora crassa	O
PHANO\|EnsemblGenome=SNOG_00758\|UniProtKB=Q0V5F6	Phaeosphaeria nodorum	O
NEUCR\|EnsemblGenome=NCU00547\|UniProtKB=Q7SFA1	Neurospora crassa	O
NEUCR\|EnsemblGenome=NCU09410\|UniProtKB=Q7S282	Neurospora crassa	O
NEUCR\|EnsemblGenome=NCU10239\|UniProtKB=A7UW67	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_05335\|UniProtKB=A7EJ42	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_14841\|UniProtKB=Q0TZY9	Phaeosphaeria nodorum	O
ASPFU\|EnsemblGenome=AFUA_5G07760\|UniProtKB=Q4WUA4	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU08292\|UniProtKB=Q7SA93	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_02715\|UniProtKB=A7EBM9	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_13029\|UniProtKB=Q0U5D5	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC14C4.07\|UniProtKB=O13714	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_03447\|UniProtKB=B6K494	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNG04530\|UniProtKB=Q5KDC3	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_11718\|UniProtKB=A0A0D1E0H6	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_00378\|UniProtKB=A0A0D1CG49	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_05840\|UniProtKB=A0A0D1DU49	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_05795\|UniProtKB=A0A0D1CJD8	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_10275\|UniProtKB=A0A0D1E4Z8	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_06515\|UniProtKB=E3K8Z4	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_85470\|UniProtKB=F4NUP9	Batrachochytrium dendrobatidis	O