PANTHER Gene Information   
Gene Symbol(s): Tph2
Organism: Mus musculus
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Gene Name: Tryptophan 5-hydroxylase 2
Gene ID: MGI:2651811
Protein ID: Q8CGV2
Persistent Id: PTN000158481
Alternate Ids:
ENSMUSG00000006764(Ensembl) 116138292(GI)
BC125430(EMBL) AAM08923(EMBL-CDS)
Tph2(Symbol) ENSMUST00000006949(Ensembl_TRS)
NP_775567(refSeq) Ntph(Synonym)
ENSMUSP00000006949(Ensembl_PRO) MGI:2651811(MGI)
TPH2_MOUSE(UniProtKB-ID) 216343(GeneID)
1.14.16.4 {ECO:0000305|PubMed:12511643}(EC) Q0VBT4(AltAccession)
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PANTHER Classification
PANTHER Family: AROMATIC AMINO ACID HYDROXYLASE (PTHR11473)
PANTHER Subfamily: TRYPTOPHAN 5-HYDROXYLASE 2 (PTHR11473:SF16)  
PANTHER GO-slim Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
monooxygenase activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component: neuron projection
PANTHER protein class: oxidoreductase
Pathway Categories: 5-Hydroxytryptamine biosynthesis
   Tryptophan hydroxylase
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen, iron ion binding, oxidoreductase activity, metal ion binding, monooxygenase activity, tryptophan 5-monooxygenase activity
GO BP Complete: serotonin biosynthetic process, aromatic amino acid metabolic process, serotonin biosynthetic process from tryptophan
GO CC Complete: neuron projection
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Metabolism, Metabolism of amine-derived hormones, Serotonin and melatonin biosynthesis, Metabolism of amino acids and derivatives

Orthologs