PANTHER Gene Information

Gene Symbol(s):

Hexim

Organism:

Drosophila melanogaster

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Gene Name:

Hexamethylene bisacetamide inducible, isoform B

Gene ID:

FBgn0038251

Protein ID:

Q8INF6

Persistent Id:

PTN000336447

Alternate Ids:

Q8INF6_DROME(UniProtKB-ID)	FBtr0082968(Ensembl_TRS)
24646884(GI)	NM_169595(refSeq)
AAN13614(EMBL-CDS)	FBgn0038251(Ensembl)
Q8INF6(Synonym)	AE014297(EMBL)
FBgn0038251(FlyBase)	FBpp0082427(Ensembl_PRO)
41778(GeneID)
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PANTHER Classification

PANTHER Family:	HEXAMETHYLENE BISACETAMIDE INDUCIBLE 1 (PTHR13469)
PANTHER Subfamily:	HEXIM P-TEFB COMPLEX SUBUNIT 1 (PTHR13469:SF8)
PANTHER GO-slim Molecular Function:	snRNA binding protein kinase inhibitor activity
PANTHER GO-slim Biological Process:	negative regulation of protein kinase activity negative regulation of cell cycle regulation of cyclin-dependent protein serine/threonine kinase activity negative regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:	nucleoplasm cytoplasm
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	7SK snRNA binding, P-TEFb complex binding, snRNA binding, cyclin-dependent protein serine/threonine kinase inhibitor activity
GO BP Complete:	negative regulation of transcription by RNA polymerase II, negative regulation of transcription elongation by RNA polymerase II
GO CC Complete:	nucleus, cytoplasm, 7SK snRNP, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=28591\|UniProtKB=Q96MH2	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000009299.4\|UniProtKB=H2QD86	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000007926.3\|UniProtKB=A0A2I2Z8E6	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000000713.4\|UniProtKB=F6YS14	Macaca mulatta	O
MOUSE\|MGI=MGI=1918309\|UniProtKB=Q3TVI4	Mus musculus	O
RAT\|RGD=1311635\|UniProtKB=B2RZ69	Rattus norvegicus	O
BOVIN\|Gene=HEXIM2\|UniProtKB=Q0X0E2	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000024974.5\|UniProtKB=F1MGX5	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000017335.5\|UniProtKB=A0A287ADJ6	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000018388.3\|UniProtKB=F7DAK1	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000026386.4\|UniProtKB=M3X9G2	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845006135.1\|UniProtKB=A0A8I3NDD7	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000024024.2\|UniProtKB=F7E882	Monodelphis domestica	O
HUMAN\|HGNC=24953\|UniProtKB=O94992	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000049378.1\|UniProtKB=K7B025	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000014370.3\|UniProtKB=G3REM4	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000062972.1\|UniProtKB=F7BGX2	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2385923\|UniProtKB=Q8R409	Mus musculus	LDO
RAT\|RGD=1559851\|UniProtKB=Q5M9G1	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000006056\|UniProtKB=Q0X0C4	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000017336.4\|UniProtKB=A0A5G2RFM4	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000000859.3\|UniProtKB=F7DSW2	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000005475.4\|UniProtKB=M3W448	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000011185.3\|UniProtKB=F7E876	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000036664.1\|UniProtKB=A0A6I8NSG0	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010023874.1\|UniProtKB=A0A8V1A277	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000016321.4\|UniProtKB=G1KSF4	Anolis carolinensis	LDO
XENLA\|Gene=hexim1.S\|UniProtKB=A0A1L8EL14	Xenopus laevis	O
XENLA\|Gene=hexim1\|UniProtKB=Q4V7W3	Xenopus laevis	LDO
XENTR\|Ensembl=ENSXETG00000047472\|UniProtKB=A0A803KC67	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000023814.1\|UniProtKB=A0A3B3HHL7	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-4637\|UniProtKB=A5D8S8	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000017511.1\|UniProtKB=W5NLV7	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118403608\|UniProtKB=A0A9J7HEQ1	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC587630\|UniProtKB=A0A7M7GR05	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00012717\|UniProtKB=Q9U2K4	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00042338\|UniProtKB=A8WK42	Caenorhabditis briggsae	LDO
ANOGA\|EnsemblGenome=AGAP002875\|UniProtKB=A7USS5	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC009262\|UniProtKB=D6WSD2	Tribolium castaneum	LDO
IXOSC\|EnsemblGenome=ISCW010097\|UniProtKB=B7Q0M5	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG189289\|UniProtKB=T1FQX3	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g212845\|UniProtKB=A7SIM0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g202514\|UniProtKB=A7RUX8	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG60587\|UniProtKB=B3S8M1	Trichoplax adhaerens	LDO