PANTHER Gene Information

Gene Symbol(s):

l(3)72Dp

Organism:

Drosophila melanogaster

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Gene Name:

folate gamma-glutamyl hydrolase

Gene ID:

FBgn0263607

Protein ID:

Q8IQM9

Persistent Id:

PTN000140102

Alternate Ids:

317887(GeneID)	514239970(GI)
AGO35569(EMBL-CDS)	FBgn0263607(Ensembl)
Q8IQM9_DROME(UniProtKB-ID)	FBgn0263607(FlyBase)
NP_730119(refSeq)	BT150130(EMBL)
FBtr0075459(Ensembl_TRS)	Q8IQM9(Synonym)
FBpp0075214(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	PROTEASE FAMILY C26 GAMMA-GLUTAMYL HYDROLASE (PTHR11315)
PANTHER Subfamily:	FOLATE GAMMA-GLUTAMYL HYDROLASE (PTHR11315:SF0)
PANTHER GO-slim Molecular Function:	cysteine-type peptidase activity
PANTHER GO-slim Biological Process:	folic acid-containing compound metabolic process
PANTHER GO-slim Cellular Component:	vacuole
PANTHER protein class:	cysteine protease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	omega peptidase activity, gamma-glutamyl-peptidase activity
GO BP Complete:	tetrahydrofolylpolyglutamate metabolic process
GO CC Complete:	vacuole

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Immune System, Innate Immune System, Neutrophil degranulation

Orthologs

ID	Organism	Type
XENLA\|Gene=ggh.2.L\|UniProtKB=A0A1L8H2F4	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-5936416\|UniProtKB=F6RT24	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000003657.2\|UniProtKB=H2LF27	Oryzias latipes	O
DANRE\|Ensembl=ENSDARG00000102758.2\|UniProtKB=A0A0G2KJW7	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000015140.1\|UniProtKB=W5NDC4	lepisosteus oculatus	O
HUMAN\|HGNC=4248\|UniProtKB=Q92820	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000020293.5\|UniProtKB=H2QW82	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000007739.3\|UniProtKB=G3QXM2	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000055148.1\|UniProtKB=F7E4X1	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1329035\|UniProtKB=Q9Z0L8	Mus musculus	LDO
RAT\|RGD=2682\|UniProtKB=Q62867	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000007534\|UniProtKB=A7YWG4	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000037637.3\|UniProtKB=A0A286ZMB2	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000014903.4\|UniProtKB=A0A9L0RJD6	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000012709.5\|UniProtKB=M3WHF8	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845029791.1\|UniProtKB=A0A8I3SCF8	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000008291.4\|UniProtKB=F7FU03	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000005049.4\|UniProtKB=F6R3K0	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010003063.1\|UniProtKB=A0A8V0X868	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000016891.4\|UniProtKB=G1KT97	Anolis carolinensis	LDO
XENLA\|Gene=ggh.L\|UniProtKB=Q6GM17	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-944415\|UniProtKB=Q5BKJ9	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000009641.2\|UniProtKB=H2M108	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-050309-193\|UniProtKB=A8KB50	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000013564.1\|UniProtKB=W5N7W5	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000013918.2\|UniProtKB=H2MFS7	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-2615\|UniProtKB=Q6NY42	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000004962.1\|UniProtKB=W5MC70	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118428959\|UniProtKB=A0A9J7NAB6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118428980\|UniProtKB=A0A9J7M5L6	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC582718\|UniProtKB=A0A7M7RC87	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC115923532\|UniProtKB=A0A7M7NS38	Strongylocentrotus purpuratus	LDO
ANOGA\|EnsemblGenome=AGAP006670\|UniProtKB=Q7Q531	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC003035\|UniProtKB=A0A139WLI6	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_315503\|UniProtKB=E9G9X9	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_302567\|UniProtKB=E9GEB1	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_307408\|UniProtKB=E9HXS3	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_305752\|UniProtKB=E9GSD7	Daphnia pulex	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g230814\|UniProtKB=A7SS46	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g182128\|UniProtKB=A7RUK5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g198458\|UniProtKB=A7RKK4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g248720\|UniProtKB=A7T4Z6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g238967\|UniProtKB=A7RKP9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g246653\|UniProtKB=A7SPT7	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG34071\|UniProtKB=B3SDN1	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_28072\|UniProtKB=A9V742	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_29193\|UniProtKB=A9VAD8	Monosiga brevicollis	LDO
DICDI\|dictyBase=DDB_G0289365\|UniProtKB=Q54HL4	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_73725\|UniProtKB=F1A4P5	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_51633\|UniProtKB=F1A4P6	Dictyostelium purpureum	LDO
DICDI\|dictyBase=DDB_G0286535\|UniProtKB=Q54LN4	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_31892\|UniProtKB=F0ZHZ6	Dictyostelium purpureum	O
PARTE\|EnsemblGenome=GSPATT00035342001\|UniProtKB=A0C5Z6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00036518001\|UniProtKB=A0CAC1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00009190001\|UniProtKB=A0CPT1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00005223001\|UniProtKB=A0BPK7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00002255001\|UniProtKB=A0DGF9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00037241001\|UniProtKB=A0CCD9	Paramecium tetraurelia	LDO
PHYRM\|Gene=H3GLE7_PHYRM\|UniProtKB=H3GLE7	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_07g315050v5\|UniProtKB=A0A2K3DIM0	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_06g275050v5\|UniProtKB=A8HVE0	Chlamydomonas reinhardtii	LDO
PHYPA\|EnsemblGenome=Pp3c17_4440\|UniProtKB=A0A2K1J2N2	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c9_2280\|UniProtKB=A9SLE6	Physcomitrella patens	O
KLENI\|Gene_ORFName=KFL_003400010\|UniProtKB=A0A1Y1IGG1	Klebsormidium nitens	O
AMBTC\|EnsemblGenome=AMTR_s00170p00050820\|UniProtKB=W1NUK7	Amborella trichopoda	LDO
MUSAM\|EnsemblGenome=Ma06_g33450\|UniProtKB=A0A804JN89	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_022538mg\|UniProtKB=K3Z7L8	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3009G199100\|UniProtKB=C5Z0Z7	Sorghum bicolor	O
SORBI\|EnsemblGenome=SORBI_3009G199200\|UniProtKB=C5Z191	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb353180\|UniProtKB=A0A1D6FTB8	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os05g0517500\|UniProtKB=Q75II5	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_2g19700v3\|UniProtKB=A0A2K2D9F9	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0077270\|UniProtKB=F2DDL5	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS1B02G350700\|UniProtKB=A0A3B5Z338	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1A02G338300\|UniProtKB=A0A3B5Y5B9	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1D02G340500\|UniProtKB=A0A3B5ZYR1	Triticum aestivum	LDO
NELNU\|Gene=LOC104591286\|UniProtKB=A0A1U7ZKK5	Nelumbo nucifera	O
NELNU\|Gene=LOC104586570\|UniProtKB=A0A1U7Z5Q4	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110795307\|UniProtKB=A0A9R0K2G3	Spinacia oleracea	O
SPIOL\|Gene=LOC110786247\|UniProtKB=A0A9R0ID30	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr15g0716621\|UniProtKB=A0A251SCE5	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C900496550\|UniProtKB=A0A9R1UK63	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C700382170\|UniProtKB=A0A9R1V0K3	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a019546mg\|UniProtKB=A0A022QEB8	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a009742mg\|UniProtKB=A0A022QNM8	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a022410mg\|UniProtKB=A0A022QEC2	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a022815mg\|UniProtKB=A0A022QIF7	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a019206mg\|UniProtKB=A0A022QFC6	Erythranthe guttata	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400035974\|UniProtKB=M1DBN5	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc07g062280.3\|UniProtKB=B2Z9Y4	Solanum lycopersicum	O
TOBAC\|Gene=LOC107799082\|UniProtKB=A0A1S4ALZ9	Nicotiana tabacum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400007066\|UniProtKB=M1AA81	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc07g062270.3\|UniProtKB=B2Z9Y3	Solanum lycopersicum	O
TOBAC\|Gene=LOC107760660\|UniProtKB=A0A1S3X2L6	Nicotiana tabacum	O
CAPAN\|EnsemblGenome=T459_24742\|UniProtKB=A0A1U8ENT1	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400021256\|UniProtKB=M1BWU0	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc10g007420.3\|UniProtKB=A0A3Q7IAQ5	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107828474\|UniProtKB=A0A1S4DD03	Nicotiana tabacum	O
TOBAC\|Gene=LOC107805981\|UniProtKB=A0A1S4B9W3	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi19g00073\|UniProtKB=F6H1W5	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_F01289\|UniProtKB=A0A059BP97	Eucalyptus grandis	O
EUCGR\|EnsemblGenome=EUGRSUZ_F01296\|UniProtKB=A0A059BN72	Eucalyptus grandis	O
EUCGR\|EnsemblGenome=EUGRSUZ_F01299\|UniProtKB=A0A059BPA1	Eucalyptus grandis	LDO
BRACM\|EnsemblGenome=Bra035056\|UniProtKB=M4F1V9	Brassica campestris	O
ARATH\|TAIR=locus=2037573\|UniProtKB=Q9ZV85	Arabidopsis thaliana	O
BRANA\|Gene_ORFName=DARMORV10_C02P35860.1\|UniProtKB=A0A078FJK7	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A02P22320.1\|UniProtKB=A0A078GK03	Brassica napus	O
BRACM\|EnsemblGenome=Bra008376\|UniProtKB=M4CVX9	Brassica campestris	O
ARATH\|TAIR=locus=2037583\|UniProtKB=Q9SYL6	Arabidopsis thaliana	O
BRACM\|EnsemblGenome=Bra035058\|UniProtKB=M4F1W1	Brassica campestris	LDO
ARATH\|TAIR=locus=2037603\|UniProtKB=O65355	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107917114\|UniProtKB=A0A1U8KHR4	Gossypium hirsutum	O
GOSHI\|Gene=LOC107934690\|UniProtKB=A0A1U8M774	Gossypium hirsutum	LDO
GOSHI\|Gene=LOC107918036\|UniProtKB=A0A1U8KKG9	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_032014\|UniProtKB=A0A061F8R2	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g023716mg\|UniProtKB=A0A067DLE2	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_011G107600v3\|UniProtKB=A0A2K1YIE2	Populus trichocarpa	LDO
POPTR\|Gene_ORFName=POPTR_012G110400\|UniProtKB=A0A3N7FU91	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_001G387100v3\|UniProtKB=A0A2K2CAI6	Populus trichocarpa	O
POPTR\|Gene_ORFName=POPTR_003G026800\|UniProtKB=A0A3N7ELP4	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_03G099600\|UniProtKB=A0A2C9W7M9	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_15G096800\|UniProtKB=A0A2C9UEQ2	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0106060\|UniProtKB=B9SEV4	Ricinus communis	LDO
SOYBN\|Gene=GGH_SOYBN\|UniProtKB=P93164	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_13G267900\|UniProtKB=A0A0R0GUI6	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_13G268000\|UniProtKB=I1M2Y6	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_2g075780\|UniProtKB=A0A072VAF3	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_2g075770\|UniProtKB=G7ITE1	Medicago truncatula	LDO
MEDTR\|EnsemblGenome=MTR_2g075790\|UniProtKB=G7ITE3	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_2g075760\|UniProtKB=G7ITD9	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr02_20460\|UniProtKB=A0A2I4GYA5	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_4G627110\|UniProtKB=A0A0A0KZI0	Cucumis sativus	O
CUCSA\|EnsemblGenome=Csa_4G627100\|UniProtKB=A0A0A0L214	Cucumis sativus	O
CUCSA\|EnsemblGenome=Csa_4G626100\|UniProtKB=A0A0A0L398	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_4G159900\|UniProtKB=M5WN15	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_423816\|UniProtKB=D8SMY2	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_177157\|UniProtKB=D8S5X6	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c26_1140\|UniProtKB=A0A2K1IBC8	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c17_12060\|UniProtKB=A0A2K1J3J7	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0032s0037\|UniProtKB=A0A2R6X6V1	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000890270\|UniProtKB=A0A1Y1I0X1	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_001320130\|UniProtKB=A0A1Y1HWJ0	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_001810210\|UniProtKB=A0A1Y1I502	Klebsormidium nitens	LDO