PANTHER Gene Information

Gene Symbol(s):

DYNLT2

Organism:

Homo sapiens

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Gene Name:

Dynein light chain Tctex-type protein 2

Gene ID:

HGNC:11695

Protein ID:

Q8IZS6

Enhancers:

View enhancers for HUMAN|HGNC=11695|UniProtKB=Q8IZS6

Genetic Variant Annotation:

Annoq

Persistent Id:

PTN002501625

Alternate Ids:

ENSG00000275368(Ensembl)	AAI13640(EMBL-CDS)
186977(MIM)	Tcte-3(Synonym)
74750798(GI)	6991(GeneID)
ENSP00000355736(Ensembl_PRO)	HGNC:11695(HGNC)
ENST00000610291(Ensembl_TRS)	DYNLT2{ECO:0000312\|HGNC:HGNC:11695}(Symbol)
NM_174910(refSeq)	AF519569(EMBL)
DYLT2_HUMAN(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN (PTHR21255)
PANTHER Subfamily:	DYNEIN LIGHT CHAIN TCTEX-TYPE PROTEIN 2 (PTHR21255:SF27)
PANTHER GO-slim Molecular Function:	protein binding
PANTHER GO-slim Biological Process:	microtubule-based movement
PANTHER GO-slim Cellular Component:	cytoplasmic dynein complex cytoplasm
PANTHER protein class:	microtubule or microtubule-binding cytoskeletal protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	protein binding, dynein intermediate chain binding
GO BP Complete:	microtubule-based movement
GO CC Complete:	cytoplasmic dynein complex, cytoplasm, membrane, microtubule

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Organelle biogenesis and maintenance, Cilium Assembly, Intraflagellar transport

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000018820.3\|UniProtKB=H2QU24	Pan troglodytes	LDO
MACMU\|Ensembl=ENSMMUG00000015340.3\|UniProtKB=A0A5F7ZYZ7	Macaca mulatta	LDO
MOUSE\|MGI=MGI=98642\|UniProtKB=P11985	Mus musculus	LDO
RAT\|RGD=1310947\|UniProtKB=A0A0G2K5Q6	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000000916.6\|UniProtKB=F1MTN5	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000004009.5\|UniProtKB=F1SC02	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000010367.6\|UniProtKB=A0A2I2V080	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000040827.1\|UniProtKB=A0A5F8H7W1	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000041227.1\|UniProtKB=A0A6I8PML0	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010004602.1\|UniProtKB=A0A8V0XK74	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000002791.3\|UniProtKB=G1KB55	Anolis carolinensis	LDO
CIOIN\|Ensembl=ENSCING00000008936.3\|UniProtKB=F6Q9R4	Ciona intestinalis	LDO
STRPU\|EnsemblGenome=LOC105440589\|UniProtKB=A0A7M7HL79	Strongylocentrotus purpuratus	LDO
DROME\|FlyBase=FBgn0033140\|UniProtKB=A0A0B4LEE2	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP009318\|UniProtKB=A7USB6	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP007597\|UniProtKB=A7UR87	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC009102\|UniProtKB=D6WUA8	Tribolium castaneum	O
HELRO\|EnsemblGenome=HelroG86178\|UniProtKB=T1G681	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG163766\|UniProtKB=T1EUG0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG193024\|UniProtKB=T1FUJ2	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG151764\|UniProtKB=T1EKM0	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g240665\|UniProtKB=A7RTY4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g124441\|UniProtKB=A7SN33	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g128942\|UniProtKB=A7SRL6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g95367\|UniProtKB=A7RW25	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g88125\|UniProtKB=A7RNP6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g75924\|UniProtKB=A7RNP5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g92462\|UniProtKB=A7RT02	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g242103\|UniProtKB=A7S132	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g128929\|UniProtKB=A7SRL5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g146279\|UniProtKB=A7T530	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g88083\|UniProtKB=A7RNP7	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g57168\|UniProtKB=A7RR16	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g128908\|UniProtKB=A7SRL9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g128923\|UniProtKB=A7SRM0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g143294\|UniProtKB=A7RW04	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g111867\|UniProtKB=A7SB66	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g181680\|UniProtKB=A7RTB6	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG57857\|UniProtKB=B3S1R5	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG58042\|UniProtKB=B3S2I9	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG17289\|UniProtKB=B3S3W4	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG58041\|UniProtKB=B3S2I8	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_26449\|UniProtKB=A9V2E3	Monosiga brevicollis	O
CRYNJ\|EnsemblGenome=CNB05675\|UniProtKB=A0A0S2LIR3	Cryptococcus neoformans	O
BATDJ\|Gene_ORFName=BATDEDRAFT_26528\|UniProtKB=F4P800	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_24237\|UniProtKB=F4P0V3	Batrachochytrium dendrobatidis	O
LEIMA\|EnsemblGenome=LMJF_28_0950\|UniProtKB=Q4Q8H2	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.02.5620\|UniProtKB=Q384P4	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_35_2910\|UniProtKB=E9AFB5	Leishmania major	O
TRYB2\|Gene_ORFName=Tb09.211.3770\|UniProtKB=Q38DD2	Trypanosoma brucei	O
GIAIC\|EnsemblGenome=GL50803_17371\|UniProtKB=A8BRE3	Giardia intestinalis	O
GIAIC\|EnsemblGenome=GL50803_6812\|UniProtKB=A8BD81	Giardia intestinalis	O
GIAIC\|EnsemblGenome=GL50803_15606\|UniProtKB=A8BPZ1	Giardia intestinalis	O
TRIV3\|Gene_ORFName=TVAG_447130\|UniProtKB=A2DRY5	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_238190\|UniProtKB=A2DD19	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_341120\|UniProtKB=A2DTS1	Trichomonas vaginalis	O
PLAF7\|EnsemblGenome=PF3D7_1147100\|UniProtKB=C6S3G7	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_1114000\|UniProtKB=Q8IIM3	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00005974001\|UniProtKB=A0C004	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00014725001\|UniProtKB=A0D9S7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00014379001\|UniProtKB=A0D8R6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00010881001\|UniProtKB=A0CV96	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00015357001\|UniProtKB=A0DBP3	Paramecium tetraurelia	O
PHYRM\|Gene=H3H199_PHYRM\|UniProtKB=H3H199	Phytophthora ramorum	O
PHYRM\|Gene=H3GW91_PHYRM\|UniProtKB=H3GW91	Phytophthora ramorum	O
PHYRM\|Gene=H3GKD8_PHYRM\|UniProtKB=H3GKD8	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_12g527750v5\|UniProtKB=O04355	Chlamydomonas reinhardtii	O
KLENI\|Gene_ORFName=KFL_003720050\|UniProtKB=A0A1Y1I9S0	Klebsormidium nitens	O
CHLRE\|EnsemblGenome=CHLRE_09g394213v5\|UniProtKB=Q6IET4	Chlamydomonas reinhardtii	O
SELML\|EnsemblGenome=SELMODRAFT_103857\|UniProtKB=D8RRC7	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_450322\|UniProtKB=D8QPL1	Selaginella moellendorffii	O
MARPO\|EnsemblGenome=MARPO_0071s0102\|UniProtKB=A0A2R6WNS0	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_003650090\|UniProtKB=A0A1Y1IHK2	Klebsormidium nitens	O