PANTHER Gene Information

Gene Symbol(s):

MED6

Organism:

Drosophila melanogaster

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Gene Name:

Mediator of RNA polymerase II transcription subunit 6

Gene ID:

FBgn0024330

Protein ID:

Q8MSX2

Persistent Id:

PTN000318584

Alternate Ids:

FBgn0024330(Ensembl)	AAN13445(EMBL-CDS)
NP_651988(refSeq)	74932477(GI)
MED6_DROME(UniProtKB-ID)	Q9VH74(AltAccession)
FBgn0024330(FlyBase)	44728(GeneID)
dMED6(Synonym)	FBpp0291087(Ensembl_PRO)
FBtr0301873(Ensembl_TRS)	MED6(Symbol)
AY118517(EMBL)
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PANTHER Classification

PANTHER Family:	MED-6-RELATED (PTHR13104)
PANTHER Subfamily:	MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 6 (PTHR13104:SF0)
PANTHER GO-slim Molecular Function:	transcription coactivator activity
PANTHER GO-slim Biological Process:	regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:	core mediator complex mediator complex
PANTHER protein class:	transcription cofactor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	transcription coregulator activity, protein binding, transcription coactivator activity
GO BP Complete:	defense response to Gram-negative bacterium, negative regulation of innate immune response, regulation of transcription by RNA polymerase II
GO CC Complete:	nucleus, core mediator complex, cytoplasm, mediator complex, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=19970\|UniProtKB=O75586	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000006496.4\|UniProtKB=H2Q8J5	Pan troglodytes	LDO
PANTR\|Ensembl=ENSPTRG00000006496.4\|UniProtKB=H2Q8J5	Pan troglodytes	LDO
MACMU\|Ensembl=ENSMMUG00000005781.4\|UniProtKB=G7MYJ9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1917042\|UniProtKB=Q921D4	Mus musculus	LDO
RAT\|RGD=1310296\|UniProtKB=B0BNE1	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000006786\|UniProtKB=Q3SZY9	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000034290.3\|UniProtKB=A0A287BBF8	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000016816.4\|UniProtKB=F6XBG0	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000013091.6\|UniProtKB=A0A337SED3	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845007660.1\|UniProtKB=A0A8I3RU25	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000007174.3\|UniProtKB=F6RC94	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000005497.2\|UniProtKB=F6X6N2	Ornithorhynchus anatinus	LDO
ANOCA\|Ensembl=ENSACAG00000043258.1\|UniProtKB=A0A803TRM1	Anolis carolinensis	LDO
XENLA\|Gene=med6.L\|UniProtKB=A0A1L8FAJ9	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-967312\|UniProtKB=B3DLE4	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000009478.2\|UniProtKB=H2M0F3	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040625-61\|UniProtKB=Q6IQ63	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000014035.1\|UniProtKB=W5N9J5	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118416429\|UniProtKB=A0A9J7L775	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC582819\|UniProtKB=A0A7M7RFJ2	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00020951\|UniProtKB=O45149	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00038292\|UniProtKB=A8XUJ6	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003164\|UniProtKB=Q9N337	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG19070\|UniProtKB=Q60WM1	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00116506\|UniProtKB=A0A2A6C0G1	Pristionchus pacificus	LDO
ANOGA\|EnsemblGenome=AGAP010034\|UniProtKB=Q7Q107	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC009982\|UniProtKB=D6WR32	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_26730\|UniProtKB=E9GCV3	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW003442\|UniProtKB=B7PA23	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG100409\|UniProtKB=T1ECZ6	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g88487\|UniProtKB=A7RP29	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG16220\|UniProtKB=B3S0T2	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_7828\|UniProtKB=A9UXJ4	Monosiga brevicollis	LDO
YEAST\|SGD=S000001100\|UniProtKB=P38782	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AAL055C\|UniProtKB=Q75EY3	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000176999\|UniProtKB=A0A1D8PKF2	Candida albicans	O
CANAL\|CGD=CAL0000201522\|UniProtKB=Q5A2Z1	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E32373g\|UniProtKB=Q6C3T0	Yarrowia lipolytica	LDO
EMENI\|Gene_ORFName=AN6549\|UniProtKB=Q5AYT1	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_6G04810\|UniProtKB=Q4WDH9	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU03809\|UniProtKB=Q9HED8	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_08842\|UniProtKB=A7EU35	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_01630\|UniProtKB=Q0V2Y4	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC1002.15c\|UniProtKB=Q9US45	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_04705\|UniProtKB=B6K7J2	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNA03340\|UniProtKB=P0CO74	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_00507\|UniProtKB=Q4PHA6	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_07694\|UniProtKB=E3KD59	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_91168\|UniProtKB=F4P9Y8	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0284421\|UniProtKB=Q54PN3	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_153426\|UniProtKB=F0ZNV8	Dictyostelium purpureum	LDO
TRIV3\|Gene_ORFName=TVAG_391440\|UniProtKB=A2DFQ7	Trichomonas vaginalis	LDO
PHYRM\|Gene=MED6\|UniProtKB=H3GGT7	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_11g467659v5\|UniProtKB=A0A2K3D7L5	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00056p00208470\|UniProtKB=U5D4G8	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_1G01770\|UniProtKB=A0A0K9PMM8	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_1G01980\|UniProtKB=A0A0K9PPS1	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma05_g25380\|UniProtKB=A0A804J8F0	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_007139mg\|UniProtKB=K3XYY1	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3010G085200\|UniProtKB=C5Z6K4	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb372970\|UniProtKB=B4FN85	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os06g0217500\|UniProtKB=Q69TG3	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_1g45820v3\|UniProtKB=I1GZS7	Brachypodium distachyon	LDO
WHEAT\|EnsemblGenome=TraesCS7A02G175100\|UniProtKB=A0A3B6RFI7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7D02G176600\|UniProtKB=A0A3B6TBM8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7B02G080200\|UniProtKB=A0A3B6SA10	Triticum aestivum	LDO
SPIOL\|Gene=LOC110793761\|UniProtKB=A0A9R0IRS3	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HannXRQ_Chr15g0489361\|UniProtKB=A0A251SAX3	Helianthus annuus	LDO
HELAN\|Gene_ORFName=HanXRQr2_Chr13g0572371\|UniProtKB=A0A9K3EF68	Helianthus annuus	LDO
HELAN\|Gene_ORFName=HanXRQr2_Chr15g0712281\|UniProtKB=A0A9K3H3T2	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C500294780\|UniProtKB=A0A9R1XDJ2	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a013894mg\|UniProtKB=A0A022QWT6	Erythranthe guttata	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a009886mg\|UniProtKB=A0A022Q4L8	Erythranthe guttata	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a018359mg\|UniProtKB=A0A022Q132	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_11047\|UniProtKB=A0A2G3A423	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG401002516\|UniProtKB=M0ZRD1	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc03g121210.3\|UniProtKB=A0A3Q7FX61	Solanum lycopersicum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400026839\|UniProtKB=M1CJS4	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc12g044640.2\|UniProtKB=A0A3Q7JWA7	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107782641\|UniProtKB=A0A1S3Z3L3	Nicotiana tabacum	O
TOBAC\|Gene=LOC107793285\|UniProtKB=A0A1S4A345	Nicotiana tabacum	LDO
VITVI\|Gene_OrderedLocusName=VIT_09s0002g02930\|UniProtKB=F6HY64	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_J02602\|UniProtKB=A0A059AI62	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00016640001\|UniProtKB=A0A078J0P0	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A05P27250.1\|UniProtKB=A0A078IND1	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra031277\|UniProtKB=A0A397ZBK5	Brassica campestris	LDO
ARATH\|TAIR=locus=2089488\|UniProtKB=F4IXJ7	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107958045\|UniProtKB=A0A1U8PDB2	Gossypium hirsutum	O
GOSHI\|Gene=LOC107891565\|UniProtKB=A0A1U8I0X9	Gossypium hirsutum	O
GOSHI\|Gene=LOC107916333\|UniProtKB=A0A1U8KK36	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_028940\|UniProtKB=A0A061GC41	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g025523mg\|UniProtKB=A0A067EUF6	Citrus sinensis	LDO
POPTR\|Gene_ORFName=POPTR_017G154400\|UniProtKB=A0A3N7G6G5	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_11G030300\|UniProtKB=A0A2C9UY15	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_04G136400\|UniProtKB=A0A2C9W3R2	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1486710\|UniProtKB=B9RQ93	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_08G199200\|UniProtKB=A0A0R0IPR5	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_0361s0030\|UniProtKB=A0A072TGD1	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_8g015230\|UniProtKB=A0A072TL70	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr12_18400\|UniProtKB=A0A2I4GHC4	Juglans regia	O
JUGRE\|EnsemblGenome=Jr12_18410\|UniProtKB=A0A2I4GHD0	Juglans regia	O
JUGRE\|EnsemblGenome=Jr12_18470\|UniProtKB=A0A2I4GHB2	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_3G434940\|UniProtKB=A0A0A0L8C2	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_3G054900\|UniProtKB=M5X0D0	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_232488\|UniProtKB=D8RVW4	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_58063\|UniProtKB=D8RT03	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c7_2870\|UniProtKB=A0A2K1KA38	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c11_22580\|UniProtKB=A0A2K1JVT5	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0012s0176\|UniProtKB=A0A2R6XJJ7	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000940320\|UniProtKB=A0A1Y1HUV0	Klebsormidium nitens	LDO