PANTHER Gene Information   
Gene Symbol(s): Chrna3
Organism: Mus musculus
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Gene Name: Neuronal acetylcholine receptor subunit alpha-3
Gene ID: MGI:87887
Protein ID: Q8R4G9
Persistent Id: PTN000436243
Alternate Ids:
110834(GeneID) AF472588(EMBL)
CHEMBL3885609(ChEMBL) ENSMUSP00000034851(Ensembl_PRO)
ENSMUST00000034851(Ensembl_TRS) Chrna3(Symbol)
BAC34740(EMBL-CDS) ACHA3(Synonym)
70778736(GI) ENSMUSG00000032303(Ensembl)
Q8BV44(AltAccession) NP_660111(refSeq)
MGI:87887(MGI) ACHA3_MOUSE(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: NEUROTRANSMITTER GATED ION CHANNEL (PTHR18945)
PANTHER Subfamily: NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-3 (PTHR18945:SF831)  
PANTHER GO-slim Molecular Function: excitatory extracellular ligand-gated monoatomic ion channel activity
transmembrane signaling receptor activity
ligand-gated monoatomic cation channel activity
transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
PANTHER GO-slim Biological Process: membrane depolarization
monoatomic ion transmembrane transport
acetylcholine receptor signaling pathway
chemical synaptic transmission
PANTHER GO-slim Cellular Component: plasma membrane signaling receptor complex
monoatomic ion channel complex
synapse
neuron projection
PANTHER protein class: ligand-gated ion channel
Pathway Categories: Nicotine pharmacodynamics pathway
   Nicotinic acetylcholine receptor alpha 3 subunit
Nicotinic acetylcholine receptor signaling pathway
   nicotinic acetylcholine receptor alpha
Nicotinic acetylcholine receptor signaling pathway
   Nicotinic Acetylcholine Receptor

GO MF Complete: monoatomic ion channel activity, transmembrane signaling receptor activity, protein binding, acetylcholine receptor activity, heterocyclic compound binding, acetylcholine-gated monoatomic cation-selective channel activity, extracellular ligand-gated monoatomic ion channel activity, acetylcholine binding, transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential, protein-containing complex binding
GO BP Complete: activation of transmembrane receptor protein tyrosine kinase activity, synaptic transmission, cholinergic, response to acetylcholine, excitatory postsynaptic potential, regulation of acetylcholine secretion, neurotransmission, behavioral response to nicotine, synaptic transmission involved in micturition, signal transduction, monoatomic ion transmembrane transport, nervous system development, response to xenobiotic stimulus, response to nicotine, presynaptic modulation of chemical synaptic transmission, regulation of dendrite morphogenesis, regulation of smooth muscle contraction, monoatomic ion transport, locomotory behavior, regulation of membrane potential, regulation of muscle contraction, acetylcholine receptor signaling pathway, membrane depolarization
GO CC Complete: nuclear speck, endoplasmic reticulum, Golgi apparatus, acetylcholine-gated channel complex, neuronal cell body, synapse, neuron projection, plasma membrane raft, plasma membrane, dopaminergic synapse, dendrite, cholinergic synapse, postsynaptic membrane, membrane, postsynaptic specialization membrane, protein-containing complex
Reactome Pathways: Presynaptic nicotinic acetylcholine receptors, Highly calcium permeable postsynaptic nicotinic acetylcholine receptors, Transmission across Chemical Synapses, Neuronal System, Postsynaptic nicotinic acetylcholine receptors, Acetylcholine binding and downstream events, Highly calcium permeable nicotinic acetylcholine receptors, Neurotransmitter receptors and postsynaptic signal transmission, Highly sodium permeable postsynaptic acetylcholine nicotinic receptors