PANTHER Gene Information

Gene Symbol(s):

fumC

Organism:

Salmonella typhimurium

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Gene Name:

Fumarate hydratase class II

Gene ID:

STM1469

Protein ID:

Q8ZPL7

Persistent Id:

PTN001688488

Alternate Ids:

WP_000259121(refSeq)	AAL20389(Ensembl_PRO)
1252987(GeneID)	FUMC_SALTY(UniProtKB-ID)
fumC{ECO:0000255\|HAMAP-Rule:MF_00743}(Symbol)	Aerobic fumarase {ECO:0000255\|HAMAP-Rule:MF_00743}(Synonym)
AE006468(EMBL)	AAL20389(Ensembl_TRS)
STM1469(Ensembl)	AAL20389(EMBL-CDS)
4.2.1.2 {ECO:0000255\|HAMAP-Rule:MF_00743}(EC)	16419988(GI)
SENT99287:STM1469-MONOMER(BioCyc)
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PANTHER Classification

PANTHER Family:	ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE (PTHR11444)
PANTHER Subfamily:	FUMARATE HYDRATASE, MITOCHONDRIAL (PTHR11444:SF1)
PANTHER GO-slim Molecular Function:	hydro-lyase activity
PANTHER GO-slim Biological Process:	tricarboxylic acid cycle dicarboxylic acid metabolic process
PANTHER GO-slim Cellular Component:
PANTHER protein class:	lyase

Pathway Categories:

TCA cycle

Fumarase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	lyase activity, fumarate hydratase activity
GO BP Complete:	malate metabolic process, tricarboxylic acid cycle, fumarate metabolic process
GO CC Complete:	cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=3700\|UniProtKB=P07954	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000002163.5\|UniProtKB=H2Q1E9	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000009996.3\|UniProtKB=G3R3D3	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000005667.4\|UniProtKB=F6VWV9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=95530\|UniProtKB=P97807	Mus musculus	LDO
RAT\|RGD=2614\|UniProtKB=P14408	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000021688.5\|UniProtKB=Q148D3	Bos taurus	LDO
HORSE\|Ensembl=ENSECAG00000020726.3\|UniProtKB=A0A9L0TAV2	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000005490.6\|UniProtKB=M3W459	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845004348.1\|UniProtKB=A0A8I3MXC4	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000007014.4\|UniProtKB=F6XCG4	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000010272.3\|UniProtKB=F6UAN3	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010009197.1\|UniProtKB=A0A8V0Y9B0	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000009712.4\|UniProtKB=G1KJB7	Anolis carolinensis	LDO
XENLA\|Gene=LOC108705582\|UniProtKB=A0A8J1KT42	Xenopus laevis	LDO
XENTR\|Gene=fh\|UniProtKB=A0A8J0QLH1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000016952.2\|UniProtKB=H2MR31	Oryzias latipes	LDO
DANRE\|Gene=LOC100535417\|UniProtKB=A0A8M1RJ00	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-010724-6\|UniProtKB=Q7SX99	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000016581.1\|UniProtKB=W5NIM8	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000008077.3\|UniProtKB=F6Z761	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118420519\|UniProtKB=A0A9J7LK59	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC580992\|UniProtKB=A0A7M7T5M9	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00001503\|UniProtKB=O17214	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00030818\|UniProtKB=A8X890	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00114387\|UniProtKB=A0A2A6BQW2	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0051874\|UniProtKB=Q8IPD2	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0036162\|UniProtKB=Q9VTI5	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0029890\|UniProtKB=Q9W3X5	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0286222\|UniProtKB=Q9W3X6	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP001884\|UniProtKB=Q7PYD5	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC013056\|UniProtKB=D6WJB5	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_46417\|UniProtKB=E9G631	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW020784\|UniProtKB=B7PXR2	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW020593\|UniProtKB=B7Q2W0	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG161397\|UniProtKB=T1ERF8	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g237597\|UniProtKB=A7SYK1	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG61292\|UniProtKB=B3SAK5	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_9875\|UniProtKB=A9V4H7	Monosiga brevicollis	LDO
YEAST\|SGD=S000006183\|UniProtKB=P08417	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_ACR013C\|UniProtKB=Q75CE3	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000183609\|UniProtKB=Q5A6L1	Candida albicans	O
CANAL\|CGD=CAL0000174516\|UniProtKB=A0A1D8PKV4	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_C06776g\|UniProtKB=Q6CCT2	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_08707\|UniProtKB=Q5ASM3	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_6G02470\|UniProtKB=Q4WCU6	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU10008\|UniProtKB=Q7S3Z6	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_05243\|UniProtKB=A7EIV0	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_07423\|UniProtKB=Q0ULE1	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPCC18.18c\|UniProtKB=O94552	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_04843\|UniProtKB=B6K7W9	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNC01700\|UniProtKB=Q5KKV6	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_10787\|UniProtKB=A0A0D1E945	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_07824\|UniProtKB=E3KB55	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_35859\|UniProtKB=F4P9U3	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0280495\|UniProtKB=Q54VA2	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_158228\|UniProtKB=F1A145	Dictyostelium purpureum	LDO
PARTE\|EnsemblGenome=GSPATT00011064001\|UniProtKB=A0CXB5	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_24123\|UniProtKB=B8C935	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3G9K7_PHYRM\|UniProtKB=H3G9K7	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_01g020223v5\|UniProtKB=A0A2K3E604	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00045p00124970\|UniProtKB=W1P313	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_91G00620\|UniProtKB=A0A0K9NJ48	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma11_g19920\|UniProtKB=A0A804L9R8	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_035345mg\|UniProtKB=K4A8Y9	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3001G378800\|UniProtKB=A0A1B6QND7	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb308640\|UniProtKB=A0A804UD95	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb016240\|UniProtKB=C0PDA6	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os03g0337900\|UniProtKB=Q10LR5	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_1g63020v3\|UniProtKB=I1H5P4	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.4HG0378120\|UniProtKB=A0A8I6XFJ2	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS4D02G170200\|UniProtKB=A0A3B6JH94	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4A02G137100\|UniProtKB=A0A0C4BJJ8	Triticum aestivum	LDO
NELNU\|Gene=LOC104598878\|UniProtKB=A0A1U7ZZY5	Nelumbo nucifera	O
NELNU\|Gene=LOC104589001\|UniProtKB=A0A1U7YY05	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110801554\|UniProtKB=A0A9R0J708	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HannXRQ_Chr06g0167721\|UniProtKB=A0A251UH44	Helianthus annuus	LDO
HELAN\|Gene_ORFName=HanXRQr2_Chr04g0177221\|UniProtKB=A0A9K3NTP5	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr06g0243261\|UniProtKB=A0A9K3IR38	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C800453770\|UniProtKB=A0A9R1UKM7	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a005258mg\|UniProtKB=A0A022S1W8	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_15664\|UniProtKB=A0A2G2Z6H8	Capsicum annuum	O
SOLLC\|EnsemblGenome=Solyc06g009820.3\|UniProtKB=A0A3Q7GNY6	Solanum lycopersicum	O
CAPAN\|EnsemblGenome=T459_08155\|UniProtKB=A0A1U8G367	Capsicum annuum	LDO
SOLLC\|EnsemblGenome=Solyc09g075450.3\|UniProtKB=A0A3Q7I742	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107776946\|UniProtKB=A0A1S3YK19	Nicotiana tabacum	O
TOBAC\|Gene=LOC107794640\|UniProtKB=A0A1S4A7M3	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi07g00362\|UniProtKB=D7U2D2	Vitis vinifera	LDO
VITVI\|EnsemblGenome=Vitvi14g00138\|UniProtKB=F6I4Q3	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_H01083\|UniProtKB=A0A059AXM5	Eucalyptus grandis	O
EUCGR\|EnsemblGenome=EUGRSUZ_H01081\|UniProtKB=A0A059AXC5	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00022565001\|UniProtKB=A0A078IZ95	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_C04P72860.1\|UniProtKB=A0A078GQ98	Brassica napus	LDO
BRANA\|Gene_ORFName=GSBRNA2T00011326001\|UniProtKB=A0A078IUR2	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00003367001\|UniProtKB=A0A078INA8	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra021400\|UniProtKB=M4DY04	Brassica campestris	O
BRACM\|EnsemblGenome=Bra004450\|UniProtKB=M4CJR6	Brassica campestris	LDO
ARATH\|TAIR=locus=2157413\|UniProtKB=Q9FI53	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2061966\|UniProtKB=P93033	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107953588\|UniProtKB=A0A1U8P249	Gossypium hirsutum	O
GOSHI\|Gene=LOC107944616\|UniProtKB=A0A1U8N801	Gossypium hirsutum	O
GOSHI\|Gene=LOC107919071\|UniProtKB=A0A1U8KNP5	Gossypium hirsutum	O
GOSHI\|Gene=LOC107953056\|UniProtKB=A0A1U8P0A2	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_004729\|UniProtKB=A0A061DYX0	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g010908mg\|UniProtKB=A0A067HGD8	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_002G201300v3\|UniProtKB=B9GSD7	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_05G000300\|UniProtKB=A0A2C9VRZ7	Manihot esculenta	LDO
MANES\|EnsemblGenome=MANES_01G223200\|UniProtKB=A0A2C9WN00	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_03G058700\|UniProtKB=A0A2C9W4Z5	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_1179670\|UniProtKB=B9SAW4	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_10G016200\|UniProtKB=K7LGW1	Glycine max	LDO
SOYBN\|EnsemblGenome=GLYMA_02G015700\|UniProtKB=A0A0R4J2N2	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_02G015800\|UniProtKB=I1JBJ2	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g087900\|UniProtKB=G7IEJ2	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr11_15270\|UniProtKB=A0A2I4EZH8	Juglans regia	LDO
JUGRE\|EnsemblGenome=Jr11_15280\|UniProtKB=A0A6P9DU55	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_4G001990\|UniProtKB=A0A0A0KWM0	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_8G265300\|UniProtKB=A0A251N5X9	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_113300\|UniProtKB=D8SC31	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_129619\|UniProtKB=D8T190	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c20_7140\|UniProtKB=A0A2K1IUD8	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c23_19500\|UniProtKB=A9S5C6	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0045s0064\|UniProtKB=A0A2R6WZY4	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_001360150\|UniProtKB=A0A1Y1I4S0	Klebsormidium nitens	LDO
METAC\|EnsemblGenome=MA_1001\|UniProtKB=Q8TS07	Methanosarcina acetivorans	LDO
STAA8\|EnsemblGenome=SAOUHSC_01983\|UniProtKB=Q2FX94	Staphylococcus aureus	LDO
LISMO\|EnsemblGenome=CAD00303\|UniProtKB=Q8Y551	Listeria monocytogenes	LDO
BACSU\|EnsemblGenome=BSU_33040\|UniProtKB=P07343	Bacillus subtilis	LDO
BACCR\|EnsemblGenome=BC_1712\|UniProtKB=Q81F85	Bacillus cereus	LDO
DEIRA\|EnsemblGenome=DR_2627\|UniProtKB=Q9RR70	Deinococcus radiodurans	LDO
SYNY3\|EnsemblGenome=BAA10200\|UniProtKB=Q55674	Synechocystis	LDO
LEPIN\|EnsemblGenome=LA_0185\|UniProtKB=Q8F9L0	Leptospira interrogans	LDO
CHLTR\|EnsemblGenome=CT_855\|UniProtKB=O84863	Chlamydia trachomatis	LDO
HELPY\|EnsemblGenome=HP_1325\|UniProtKB=O25883	Helicobacter pylori	LDO
NEIMB\|EnsemblGenome=NMB1458\|UniProtKB=Q9JYR9	Neisseria meningitidis serogroup b	LDO
BRADU\|EnsemblGenome=BAC45551\|UniProtKB=Q89XM2	Bradyrhizobium diazoefficiens	LDO
COXBU\|EnsemblGenome=CBU_1096\|UniProtKB=Q83CL8	Coxiella burnetii	LDO
HAEIN\|EnsemblGenome=HI_1398\|UniProtKB=P71384	Haemophilus influenzae	LDO
PSEAE\|EnsemblGenome=PA0854\|UniProtKB=Q9I587	Pseudomonas aeruginosa	LDO
YERPE\|EnsemblGenome=YP_2061\|UniProtKB=Q8ZEB6	Yersinia pestis	LDO
ECOLI\|EnsemblGenome=BAA15349\|UniProtKB=P05042	Escherichia coli	LDO