PANTHER Gene Information

Gene Symbol(s):

ubc-25

Organism:

Caenorhabditis elegans

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Gene Name:

Ubiquitin-conjugating enzyme E2 25

Gene ID:

WBGene00006720

Protein ID:

Q93571

Persistent Id:

PTN000630919

Alternate Ids:

AF537093(EMBL)	WBGene00006720(WormBase)
2.3.2.23 {ECO:0000255}(EC)	NP_492764(refSeq)
AAO85552(EMBL-CDS)	WBGene00006720(Ensembl)
ubc-25{ECO:0000312\|WormBase:F25H2.8}(Symbol)	F25H2.8(Ensembl_TRS)
F25H2.8(Ensembl_PRO)	E2 ubiquitin-conjugating enzyme 25(Synonym)
UBC25_CAEEL(UniProtKB-ID)	F25H2(WormBase_TRS)
CE34543(WormBase_PRO)	172941(GeneID)
Q86M58(AltAccession)	75018686(GI)
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PANTHER Classification

PANTHER Family:	UBIQUITIN-CONJUGATING ENZYME E2 (PTHR24068)
PANTHER Subfamily:	UBIQUITIN-CONJUGATING ENZYME E2Q 2 ISOFORM 1 (PTHR24068:SF33)
PANTHER GO-slim Molecular Function:	ubiquitin conjugating enzyme activity
PANTHER GO-slim Biological Process:	protein polyubiquitination
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	ubiquitin-protein ligase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ATP binding, ubiquitin conjugating enzyme activity, transferase activity
GO BP Complete:	locomotion, protein polyubiquitination, protein ubiquitination
GO CC Complete:	nucleus, cytoplasm, cytosol, neuronal cell body

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Protein ubiquitination, Class I MHC mediated antigen processing & presentation, Synthesis of active ubiquitin: roles of E1 and E2 enzymes, Immune System, Antigen processing: Ubiquitination & Proteasome degradation, Post-translational protein modification, Metabolism of proteins, Adaptive Immune System

Orthologs

ID	Organism	Type
HUMAN\|HGNC=15698\|UniProtKB=Q7Z7E8	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000001387.3\|UniProtKB=H2Q055	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000005627.3\|UniProtKB=G3QS84	Gorilla gorilla gorilla	O
MOUSE\|MGI=MGI=1917343\|UniProtKB=Q7TSS2	Mus musculus	O
RAT\|RGD=1305305\|UniProtKB=B2GV55	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000007515.5\|UniProtKB=E1BIE5	Bos taurus	O
HORSE\|Ensembl=ENSECAG00000016647.4\|UniProtKB=A0A9L0TB67	Equus caballus	O
MONDO\|Ensembl=ENSMODG00000017185.3\|UniProtKB=F6XXS8	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000040300.1\|UniProtKB=A0A6I8PI32	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010027902.1\|UniProtKB=A0A1D5NVE2	Gallus gallus	O
HUMAN\|HGNC=19248\|UniProtKB=Q8WVN8	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000007308.5\|UniProtKB=A0A2I3SUV9	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000001079.3\|UniProtKB=A0A2I2Z4A2	Gorilla gorilla gorilla	LDO
MOUSE\|MGI=MGI=2141773\|UniProtKB=Q8BW45	Mus musculus	O
MOUSE\|MGI=MGI=2388672\|UniProtKB=Q8K2Z8	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000004024\|UniProtKB=Q32L27	Bos taurus	LDO
MONDO\|Ensembl=ENSMODG00000011919.3\|UniProtKB=F6XXT8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000006967.4\|UniProtKB=F7E1K3	Ornithorhynchus anatinus	LDO
ORYLA\|Ensembl=ENSORLG00000004875.2\|UniProtKB=A0A3B3IN86	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000013097.2\|UniProtKB=A0A3B3IG49	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-1919\|UniProtKB=X1WFM4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000014289.1\|UniProtKB=W5NAD4	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000008673.3\|UniProtKB=F6ZF50	Ciona intestinalis	LDO
STRPU\|EnsemblGenome=LOC581772\|UniProtKB=A0A7M7RBQ7	Strongylocentrotus purpuratus	LDO
CAEBR\|WormBase=WBGene00025333\|UniProtKB=A8WS63	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00116303\|UniProtKB=A0A2A6BGR2	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0023528\|UniProtKB=Q29R09	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP001452\|UniProtKB=Q7PUY5	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC030776\|UniProtKB=D6WAJ7	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_215319\|UniProtKB=E9H2H9	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW000642\|UniProtKB=B7P1N9	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG90827\|UniProtKB=T1G7W7	helobdella robusta	LDO
HELRO\|EnsemblGenome=HelroG148094\|UniProtKB=T1EK46	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g126045\|UniProtKB=A7SPH8	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG21996\|UniProtKB=B3RR56	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_14240\|UniProtKB=A9USV4	Monosiga brevicollis	O
SCLS1\|EnsemblGenome=SS1G_05995\|UniProtKB=A7EKZ8	Sclerotinia sclerotiorum	O
THAPS\|EnsemblGenome=THAPSDRAFT_23115\|UniProtKB=B8C5U5	Thalassiosira pseudonana	O