PANTHER Gene Information

Gene Symbol(s):

IDH5

Organism:

Arabidopsis thaliana

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Gene Name:

Isocitrate dehydrogenase [NAD] catalytic subunit 5, mitochondrial

Gene ID:

2142604

Protein ID:

Q945K7

Persistent Id:

PTN000216967

Alternate Ids:

831884(GeneID)	15724320(GI)
locus:2142604(TAIR)	AT5G03290(Ensembl_PRO)
IDH5_ARATH(UniProtKB-ID)	Isocitric dehydrogenase 5(Synonym)
NM_120407(refSeq)	Q9LZG1(AltAccession)
IDH5(Symbol)	MetaCyc:AT5G03290-MON(BioCyc)
BT008460(EMBL)	AT5G03290(Ensembl_TRS)
AT5G03290(Ensembl)	AAL06553(EMBL-CDS)
1.1.1.41 {ECO:0000305\|PubMed:16527867}(EC)
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PANTHER Classification

PANTHER Family:	DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE (PTHR11835)
PANTHER Subfamily:	ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL (PTHR11835:SF34)
PANTHER GO-slim Molecular Function:	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
PANTHER GO-slim Biological Process:	secondary alcohol metabolic process tricarboxylic acid cycle carboxylic acid metabolic process
PANTHER GO-slim Cellular Component:
PANTHER protein class:	dehydrogenase

Pathway Categories:

Leucine biosynthesis

3-Isopropylmalate dehydrogenase

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	magnesium ion binding, ATP binding, isocitrate dehydrogenase (NAD+) activity, zinc ion binding, NAD binding
GO BP Complete:	isocitrate metabolic process, tricarboxylic acid cycle
GO CC Complete:	mitochondrion, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
IXOSC\|EnsemblGenome=ISCW016729\|UniProtKB=B7P8B1	Ixodes scapularis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g226098\|UniProtKB=A8DWU0	Nematostella vectensis	O
MONBE\|EnsemblGenome=MONBRDRAFT_31232\|UniProtKB=A9USI1	Monosiga brevicollis	O
HUMAN\|HGNC=5384\|UniProtKB=P50213	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000007336.6\|UniProtKB=H2Q9W0	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000002227.3\|UniProtKB=A0A2I2ZTP2	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000011838.4\|UniProtKB=I2CW30	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1915084\|UniProtKB=Q9D6R2	Mus musculus	LDO
RAT\|RGD=70889\|UniProtKB=Q99NA5	Rattus norvegicus	LDO
BOVIN\|Gene=IDH3A\|UniProtKB=P41563	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000006227.4\|UniProtKB=Q148J8	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000032498.3\|UniProtKB=A0A480S312	Sus scrofa	LDO
PIG\|Gene=IDH3A\|UniProtKB=P56471	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000015278.4\|UniProtKB=A0A9L0SWI4	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000010515.5\|UniProtKB=M3WDF0	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845006975.1\|UniProtKB=A0A8I3NG17	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000011642.3\|UniProtKB=F6TJ83	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000014728.4\|UniProtKB=F7EQJ8	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010024322.1\|UniProtKB=A0A8V1A4J0	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000006101.4\|UniProtKB=H9GB07	Anolis carolinensis	LDO
XENLA\|Gene=idh3a.L\|UniProtKB=A0A8J0URS2	Xenopus laevis	O
XENLA\|Gene=idh3a.S\|UniProtKB=A0A8J0UMM0	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-943186\|UniProtKB=Q6P314	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000027001.1\|UniProtKB=A0A3B3H4B4	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-1007\|UniProtKB=Q6NV33	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000014826.1\|UniProtKB=W5NCA0	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000007286.3\|UniProtKB=F6SUS9	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118410079\|UniProtKB=A0A9J7KP58	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC587700\|UniProtKB=A0A7M7TGX8	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00009664\|UniProtKB=Q93714	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00033447\|UniProtKB=A8XFX3	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00278357\|UniProtKB=A0A2A6CCQ7	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0035005\|UniProtKB=Q9W172	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0052026\|UniProtKB=Q8T0R3	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0027291\|UniProtKB=Q9VWH4	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP002728\|UniProtKB=F5HKN6	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC004962\|UniProtKB=D6WCZ6	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_222251\|UniProtKB=E9G2H1	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW004116\|UniProtKB=B7PHM9	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG185474\|UniProtKB=T1FMV2	helobdella robusta	LDO
TRIAD\|EnsemblGenome=TriadG54615\|UniProtKB=B3RSJ1	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_19354\|UniProtKB=A9UQS3	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_6048\|UniProtKB=A9URF0	Monosiga brevicollis	LDO
YEAST\|SGD=S000001356\|UniProtKB=P40495	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ADL214C\|UniProtKB=Q75AY4	Eremothecium gossypii	O
CANAL\|CGD=CAL0000198832\|UniProtKB=Q5A9D9	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_D10593g\|UniProtKB=Q6C9K0	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_05206\|UniProtKB=G5EB15	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_6G07390\|UniProtKB=Q4WN70	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU02954\|UniProtKB=Q7SH15	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_02537\|UniProtKB=A7EB51	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_01047\|UniProtKB=Q0V4L7	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC31G5.04\|UniProtKB=O14104	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_00502\|UniProtKB=B6JVT5	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CND03850\|UniProtKB=Q5KI84	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_04873\|UniProtKB=A0A0D1CIK8	Ustilago maydis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_85530\|UniProtKB=F4NTN8	Batrachochytrium dendrobatidis	O
YEAST\|SGD=S000005662\|UniProtKB=P28241	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AFR137C\|UniProtKB=Q754D3	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000183793\|UniProtKB=A0A1D8PGS5	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_D06303g\|UniProtKB=Q6CA33	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_01003\|UniProtKB=C8VU63	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_1G12800\|UniProtKB=E9QYY1	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU07697\|UniProtKB=Q7S9K8	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_09958\|UniProtKB=A7EX97	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_06082\|UniProtKB=Q0UQ82	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC902.05c\|UniProtKB=Q9USP8	Schizosaccharomyces pombe	LDO
CRYNJ\|EnsemblGenome=CNA04610\|UniProtKB=Q5KP10	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_01328\|UniProtKB=A0A0D1E633	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_01926\|UniProtKB=E3JTK8	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_33391\|UniProtKB=F4P5V7	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0271344\|UniProtKB=Q55BI2	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_80730\|UniProtKB=F0ZRC6	Dictyostelium purpureum	LDO
PARTE\|EnsemblGenome=GSPATT00023050001\|UniProtKB=A0E3L0	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00025896001\|UniProtKB=A0EE35	Paramecium tetraurelia	O
CHLRE\|EnsemblGenome=CHLRE_02g143250v5\|UniProtKB=A0A2K3E3Z0	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00001p00200380\|UniProtKB=W1NLC5	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_307G00010\|UniProtKB=A0A0K9PC97	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma10_g11000\|UniProtKB=A0A804KUW6	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma06_g14450\|UniProtKB=A0A804JG73	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_001950mg\|UniProtKB=K3XJ77	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3003G129900\|UniProtKB=C5XH85	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb332780\|UniProtKB=B6TJM1	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb128830\|UniProtKB=B4FAD4	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os01g0276100\|UniProtKB=Q9SDG5	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g43300v3\|UniProtKB=I1I9M7	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0209680\|UniProtKB=G9AYJ6	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS2B02G592100\|UniProtKB=W5BEC0	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2A02G591600\|UniProtKB=A0A3B6B9T4	Triticum aestivum	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0586240\|UniProtKB=A0A287U3J5	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS6B02G235000\|UniProtKB=A0A3B6PLE4	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS6A02G198200\|UniProtKB=A0A3B6NR24	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS6D02G183400\|UniProtKB=A0A3B6QE47	Triticum aestivum	LDO
NELNU\|Gene=LOC104601278\|UniProtKB=A0A1U8AKP2	Nelumbo nucifera	LDO
NELNU\|Gene=LOC104599244\|UniProtKB=A0A1U8ACV7	Nelumbo nucifera	O
SPIOL\|Gene=LOC110796048\|UniProtKB=A0A9R0IW93	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr01g0040221\|UniProtKB=A0A251VT73	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr11g0514991\|UniProtKB=A0A251TEL2	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C100021770\|UniProtKB=A0A9R1WCP8	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a025927mg\|UniProtKB=A0A022R4D0	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a008944mg\|UniProtKB=A0A022R3E5	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a008537mg\|UniProtKB=A0A022RDV5	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_06457\|UniProtKB=A0A2G3AAU7	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_06338\|UniProtKB=A0A2G3AAI2	Capsicum annuum	LDO
SOLTU\|Gene=LEU3_SOLTU\|UniProtKB=P29696	Solanum tuberosum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400026246\|UniProtKB=M1CHE3	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc08g077920.3\|UniProtKB=A0A3Q7HUE5	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107813330\|UniProtKB=A0A1S4BYT9	Nicotiana tabacum	O
TOBAC\|Gene=LOC107814521\|UniProtKB=A0A1S4C2Z5	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi08g01021\|UniProtKB=D7TQM9	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_A01135\|UniProtKB=A0A059DEF9	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00080014001\|UniProtKB=A0A078I5B6	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00037726001\|UniProtKB=A0A078JB58	Brassica napus	O
BRACM\|EnsemblGenome=Bra028843\|UniProtKB=M4EJ77	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_C09P73490.1\|UniProtKB=A0A078FAF4	Brassica napus	O
BRACM\|EnsemblGenome=Bra009537\|UniProtKB=A0A397XQZ6	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_A03P01100.1\|UniProtKB=A0A078FD30	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra005736\|UniProtKB=M4CNE8	Brassica campestris	LDO
GOSHI\|Gene=LOC107891139\|UniProtKB=A0A1U8I6E6	Gossypium hirsutum	O
GOSHI\|Gene=LOC107943579\|UniProtKB=A0A1U8N4S6	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_022180\|UniProtKB=A0A061ETX7	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g017413mg\|UniProtKB=A0A067E9Z4	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_006G126700v3\|UniProtKB=A0A2K2A1A6	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_016G091200v3\|UniProtKB=B9IFP1	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_09G063800\|UniProtKB=A0A2C9V8F3	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_08G008500\|UniProtKB=A0A2C9VDL7	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1355470\|UniProtKB=B9S0K1	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_13G144900\|UniProtKB=I1LZ93	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_10G058100\|UniProtKB=I1L903	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g064070\|UniProtKB=G7IAA3	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_3g101470\|UniProtKB=G7J6B4	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr04_04470\|UniProtKB=A0A2I4H5Q2	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_6G446300\|UniProtKB=A0A0A0KF41	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_6G235200\|UniProtKB=M5VYP8	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_160113\|UniProtKB=D8T1A5	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_233612\|UniProtKB=D8SC18	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c9_16040\|UniProtKB=A0A2K1K3E4	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c15_3920\|UniProtKB=A9SIP7	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c9_4370\|UniProtKB=A9TBJ2	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0002s0215\|UniProtKB=A0A2R6XUH9	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000230270\|UniProtKB=A0A1Y1HT94	Klebsormidium nitens	LDO
NITMS\|EnsemblGenome=Nmar_1379\|UniProtKB=A9A2N6	Nitrosopumilus maritimus	O
METAC\|EnsemblGenome=MA_4265\|UniProtKB=Q8TI91	Methanosarcina acetivorans	O
NITMS\|EnsemblGenome=Nmar_1069\|UniProtKB=A9A4I7	Nitrosopumilus maritimus	LDO
KORCO\|EnsemblGenome=Kcr_0970\|UniProtKB=B1L5I7	Korarchaeum cryptofilum	O
KORCO\|EnsemblGenome=Kcr_0190\|UniProtKB=B1L3C1	Korarchaeum cryptofilum	LDO
SACS2\|EnsemblGenome=SSO0723\|UniProtKB=Q9UXB2	Sulfolobus solfataricus	LDO
PYRAE\|EnsemblGenome=PAE1995\|UniProtKB=Q8ZW34	Pyrobaculum aerophilum	LDO
METAC\|EnsemblGenome=MA_3748\|UniProtKB=Q8TJN2	Methanosarcina acetivorans	LDO
METJA\|EnsemblGenome=MJ_1596\|UniProtKB=Q58991	Methanocaldococcus jannaschii	LDO
METJA\|EnsemblGenome=MJ_0720\|UniProtKB=Q58130	Methanocaldococcus jannaschii	O
THEKO\|EnsemblGenome=TK0280\|UniProtKB=Q5JFV8	Thermococcus kodakaraensis	LDO
CHLAA\|EnsemblGenome=Caur_0331\|UniProtKB=A9WD13	Chloroflexus aurantiacus	LDO
CLOBH\|Gene_OrderedLocusName=CBO0419\|UniProtKB=A5HYW3	Clostridium botulinum	LDO
DEIRA\|EnsemblGenome=DR_1674\|UniProtKB=Q9RTT2	Deinococcus radiodurans	LDO
GLOVI\|Gene=icd\|UniProtKB=Q7NC91	Gloeobacter violaceus	LDO
THEYD\|EnsemblGenome=THEYE_A1278\|UniProtKB=B5YFP4	Thermodesulfovibrio yellowstonii	LDO
BRADU\|Gene=Q89RJ1_BRADU\|UniProtKB=Q89RJ1	Bradyrhizobium diazoefficiens	O
BRADU\|Gene=Q89RM2_BRADU\|UniProtKB=Q89RM2	Bradyrhizobium diazoefficiens	O
BRADU\|Gene=leuB\|UniProtKB=Q89GM4	Bradyrhizobium diazoefficiens	LDO
SHEON\|Gene_OrderedLocusName=SO_1538\|UniProtKB=Q8EGQ7	Shewanella oneidensis	LDO
XANCP\|EnsemblGenome=XCC0967\|UniProtKB=Q8PBY9	Xanthomonas campestris	LDO