PANTHER Gene Information

Gene Symbol(s):

PGRP-LA

Organism:

Drosophila melanogaster

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Gene Name:

Peptidoglycan-recognition protein LA

Gene ID:

FBgn0035975

Protein ID:

Q95T64

Persistent Id:

PTN000111770

Alternate Ids:

PGRP-LA(Symbol)	23093803(GI)
AF207535(EMBL)	PGPLA(Synonym)
Q9BLX5(AltAccession)	PGPLA_DROME(UniProtKB-ID)
39062(GeneID)	AAF50304(EMBL-CDS)
FBgn0035975(Ensembl)	FBgn0035975(FlyBase)
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PANTHER Classification

PANTHER Family:	PEPTIDOGLYCAN RECOGNITION PROTEIN (PTHR11022)
PANTHER Subfamily:	PEPTIDOGLYCAN-RECOGNITION PROTEIN LA (PTHR11022:SF76)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	defense/immunity protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	zinc ion binding
GO BP Complete:	response to bacterium, immune response, positive regulation of peptidoglycan recognition protein signaling pathway, defense response to Gram-negative bacterium, innate immune response
GO CC Complete:	plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=30013\|UniProtKB=Q96PD5	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000010624.3\|UniProtKB=H2QFM5	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000000564.3\|UniProtKB=G3SBB6	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000003031.4\|UniProtKB=F6YYJ9	Macaca mulatta	O
MOUSE\|MGI=MGI=1928099\|UniProtKB=Q8VCS0	Mus musculus	O
RAT\|RGD=1359183\|UniProtKB=M0R485	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000012280.6\|UniProtKB=E1BH94	Bos taurus	O
PIG\|Gene=PGLYRP2\|UniProtKB=Q866Y3	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000025560.4\|UniProtKB=A0A5K1UBC7	Sus scrofa	O
FELCA\|Ensembl=ENSFCAG00000013649.5\|UniProtKB=M3WJ85	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845016433.1\|UniProtKB=A0A8I3NUZ6	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000014610.4\|UniProtKB=F6ZE34	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000005133.4\|UniProtKB=F6WGK2	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010003811.1\|UniProtKB=A0A8V0XHG1	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000016557.4\|UniProtKB=A0A803THY7	Anolis carolinensis	O
XENLA\|Gene=pglyrp2.L\|UniProtKB=A0A8J0US95	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-5779913\|UniProtKB=A8QN48	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000016356.2\|UniProtKB=H2MP17	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-071227-2\|UniProtKB=A0A0R4IJX9	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000000315.2\|UniProtKB=H2L3Q8	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-071227-1\|UniProtKB=Q1W1Y3	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000006717.1\|UniProtKB=W5MIA5	lepisosteus oculatus	O
HUMAN\|HGNC=30014\|UniProtKB=Q96LB9	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000001342.3\|UniProtKB=H2Q024	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000000853.3\|UniProtKB=G3QEY4	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000053940.1\|UniProtKB=F6YQC2	Macaca mulatta	O
MOUSE\|MGI=MGI=2685266\|UniProtKB=A1A547	Mus musculus	O
RAT\|RGD=1593164\|UniProtKB=D3ZYV3	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000021443.5\|UniProtKB=E1BJ76	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000027322.4\|UniProtKB=I3LN36	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000011884.4\|UniProtKB=F7BEB8	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000002484.6\|UniProtKB=A0A337SE72	Felis catus	O
HUMAN\|HGNC=30015\|UniProtKB=Q96LB8	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000001344.5\|UniProtKB=H2Q025	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000000856.3\|UniProtKB=G3QEY6	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000006865.4\|UniProtKB=F7F8I2	Macaca mulatta	O
MOUSE\|MGI=MGI=2686324\|UniProtKB=Q0VB07	Mus musculus	O
RAT\|RGD=1308520\|UniProtKB=D4AEA3	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000054765.1\|UniProtKB=A0A3Q1MPE3	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000006587.5\|UniProtKB=F1SFU8	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000011674.3\|UniProtKB=F7ANQ4	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000011704.5\|UniProtKB=M3WFL2	Felis catus	O
MONDO\|Ensembl=ENSMODG00000017413.3\|UniProtKB=F7AJG4	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000050037.1\|UniProtKB=A0A6I8PPD0	Ornithorhynchus anatinus	O
HUMAN\|HGNC=8904\|UniProtKB=O75594	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000011175.6\|UniProtKB=H2QGM5	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000011126.3\|UniProtKB=G3R6A3	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000008742.4\|UniProtKB=H9H398	Macaca mulatta	O
MOUSE\|MGI=MGI=1345092\|UniProtKB=O88593	Mus musculus	O
RAT\|RGD=621429\|UniProtKB=Q9JLN4	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000002635\|UniProtKB=Q8SPP7	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000038688.3\|UniProtKB=A0A286ZI97	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000032321.3\|UniProtKB=A0A5F5Q2T7	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000039739.2\|UniProtKB=F6QB61	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000028691.4\|UniProtKB=M3WZT2	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845004551.1\|UniProtKB=A0A8I3MTX9	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000021527.2\|UniProtKB=F7FSD2	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000049441.1\|UniProtKB=A0A6I8P9R1	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000039867.1\|UniProtKB=A0A6I8P284	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000030126.2\|UniProtKB=K7EDK3	Ornithorhynchus anatinus	O
ANOCA\|Ensembl=ENSACAG00000000025.4\|UniProtKB=H9G372	Anolis carolinensis	O
XENLA\|Gene=LOC108700665\|UniProtKB=A0A1L8F3H7	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000039671\|UniProtKB=A0A803JPG3	Xenopus tropicalis	O
XENLA\|Gene=pglyrp1.S\|UniProtKB=Q5PPZ4	Xenopus laevis	O
XENLA\|Gene=pglyrp1.L\|UniProtKB=A0A8J0TM72	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-491319\|UniProtKB=A0A803JNK5	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000013289.2\|UniProtKB=H2MDK5	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-050419-71\|UniProtKB=Q1W1Y2	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000014823.1\|UniProtKB=W5NC92	lepisosteus oculatus	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_76871\|UniProtKB=C3YN89	Branchiostoma floridae	O
BRAFL\|Gene=LOC118425176\|UniProtKB=A0A9J7N4M1	Branchiostoma floridae	O
BRAFL\|Gene=LOC118426144\|UniProtKB=A0A9J7LZJ6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118406003\|UniProtKB=A0A9J7HLF5	Branchiostoma floridae	O
BRAFL\|Gene=LOC118431182\|UniProtKB=A0A9J7NC30	Branchiostoma floridae	O
BRAFL\|Gene=LOC118405853\|UniProtKB=A0A9J7HKZ7	Branchiostoma floridae	O
BRAFL\|Gene=LOC118416065\|UniProtKB=A0A9J7MRX9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118422467\|UniProtKB=A0A9J7LPE7	Branchiostoma floridae	O
BRAFL\|Gene=LOC118427931\|UniProtKB=A0A9J7M5L9	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC100892590\|UniProtKB=A0A7M7PEC7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115919963\|UniProtKB=A0A7M7N395	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC591777\|UniProtKB=A0A7M7STK5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC764572\|UniProtKB=A0A7M7N4R5	Strongylocentrotus purpuratus	O
ANOGA\|EnsemblGenome=AGAP005205\|UniProtKB=A0A2Y9D1X5	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC010508\|UniProtKB=D6WE12	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC002790\|UniProtKB=D6WIN7	Tribolium castaneum	O
IXOSC\|EnsemblGenome=ISCW024689\|UniProtKB=B7Q5J1	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW004389\|UniProtKB=B7PER7	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW022212\|UniProtKB=B7QC27	Ixodes scapularis	O