PANTHER Gene Information

Gene Symbol(s):

ngn-1

Organism:

Caenorhabditis elegans

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Gene Name:

Helix-loop-helix protein ngn-1

Gene ID:

WBGene00003595

Protein ID:

Q95XG7

Persistent Id:

PTN000446077

Alternate Ids:

CE26560(WormBase_PRO)	NGN1_CAEEL(UniProtKB-ID)
177045(GeneID)	WBGene00003595(WormBase)
CCD74131(EMBL-CDS)	BX284604(EMBL)
351051432(GI)	WBGene00003595(Ensembl)
Y69A2AR.29(Ensembl_TRS)	NGN1(Synonym)
Y69A2AR.29(Ensembl_PRO)	ngn-1{ECO:0000312\|WormBase:Y69A2AR.29}(Symbol)
NM_067835(refSeq)	Y69A2AR(WormBase_TRS)
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PANTHER Classification

PANTHER Family:	BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED (PTHR19290)
PANTHER Subfamily:	BASIC HELIX-LOOP-HELIX NEURAL TRANSCRIPTION FACTOR TAP (PTHR19290:SF163)
PANTHER GO-slim Molecular Function:	DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding
PANTHER GO-slim Biological Process:	axon development positive regulation of transcription by RNA polymerase II sensory organ development
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	basic helix-loop-helix transcription factor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA binding, protein dimerization activity, DNA-binding transcription factor activity, RNA polymerase II-specific, E-box binding
GO BP Complete:	negative regulation of gliogenesis, axon development, anatomical structure morphogenesis, positive regulation of transcription by RNA polymerase II, sensory organ development
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=13806\|UniProtKB=Q9Y4Z2	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000002576.5\|UniProtKB=H2RFA6	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000036451.1\|UniProtKB=A0A2I2ZFA1	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000008956.3\|UniProtKB=F7EV54	Macaca mulatta	O
MOUSE\|MGI=MGI=893591\|UniProtKB=P70661	Mus musculus	O
RAT\|RGD=631350\|UniProtKB=O08718	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000006431.5\|UniProtKB=F1MGY3	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000034488.2\|UniProtKB=A0A287AZY9	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000017888.2\|UniProtKB=A0A3Q2HLA3	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000022498.3\|UniProtKB=A0A2I2UBD4	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845003696.1\|UniProtKB=A0A8I3N6D3	Canis lupus familiaris	O
ANOCA\|Ensembl=ENSACAG00000038513.1\|UniProtKB=A0A803TE51	Anolis carolinensis	O
XENLA\|Gene=neurog1.L\|UniProtKB=A0A1L8GWW0	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-491452\|UniProtKB=B0JYV1	Xenopus tropicalis	O
XENLA\|Gene=neurog3.L\|UniProtKB=A0A1L8FK38	Xenopus laevis	O
XENLA\|Gene=neurog3.S\|UniProtKB=A0A8J0T4E1	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-876279\|UniProtKB=A0A6I8PUY5	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000028099.1\|UniProtKB=A0A3B3HLS4	Oryzias latipes	O
LEPOC\|Ensembl=ENSLOCG00000011531.1\|UniProtKB=W5N0K7	lepisosteus oculatus	O
HUMAN\|HGNC=7764\|UniProtKB=Q92886	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000017258.5\|UniProtKB=H2QRI9	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000002841.3\|UniProtKB=G3RNU4	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000004770.3\|UniProtKB=F6SM19	Macaca mulatta	O
MOUSE\|MGI=MGI=107754\|UniProtKB=P70660	Mus musculus	O
RAT\|RGD=3167\|UniProtKB=P70595	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000003331.5\|UniProtKB=F1MZC4	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000014309.2\|UniProtKB=F1RHB5	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000010202.4\|UniProtKB=A0A3Q2HN79	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000038610.3\|UniProtKB=A0A5F5XQK0	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845013951.1\|UniProtKB=A0A8I3S0H8	Canis lupus familiaris	O
HUMAN\|HGNC=13805\|UniProtKB=Q9H2A3	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000047838.1\|UniProtKB=A0A2I3T5C2	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000038276.1\|UniProtKB=A0A2I2ZSF2	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000014078.3\|UniProtKB=F7CE59	Macaca mulatta	LDO
MOUSE\|MGI=MGI=109619\|UniProtKB=P70447	Mus musculus	LDO
RAT\|RGD=1309061\|UniProtKB=D4A2E3	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000015259.5\|UniProtKB=E1BHS2	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000033479.1\|UniProtKB=A0A287AMU8	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000035491.2\|UniProtKB=A0A3Q2HYI3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000010711.5\|UniProtKB=M3WDS4	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845016784.1\|UniProtKB=A0A8I3P8Z6	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000005712.2\|UniProtKB=F6U4A8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000042970.1\|UniProtKB=A0A6I8NBQ6	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000047301.1\|UniProtKB=A0A6I8N7A7	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000038031.1\|UniProtKB=A0A6I8P7X4	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000047178.1\|UniProtKB=A0A6I8P2S1	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010013092.1\|UniProtKB=Q9PWP1	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010020528.1\|UniProtKB=A0A8V0ZEX7	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010005569.1\|UniProtKB=Q9YH82	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000001255.2\|UniProtKB=H9G4U7	Anolis carolinensis	LDO
ANOCA\|Ensembl=ENSACAG00000023148.1\|UniProtKB=G1KZC9	Anolis carolinensis	LDO
XENLA\|Gene=neurog2.S\|UniProtKB=P70051	Xenopus laevis	O
XENLA\|Gene=neurog2.L\|UniProtKB=P70050	Xenopus laevis	LDO
XENTR\|Ensembl=ENSXETG00000046744\|UniProtKB=A0A803K2L4	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000020531.2\|UniProtKB=H2N1X3	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-010608-4\|UniProtKB=B3DFN6	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-990415-174\|UniProtKB=O42606	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000011560.1\|UniProtKB=W5N0P0	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000004039.3\|UniProtKB=F6RYF3	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_117981\|UniProtKB=C3Z5Z3	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC100890077\|UniProtKB=A0A7M7GJN3	Strongylocentrotus purpuratus	LDO
CAEBR\|WormBase=WBGene00034567\|UniProtKB=A8XJ45	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00277155\|UniProtKB=A0A2A6CBF4	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0015550\|UniProtKB=O16867	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP005930\|UniProtKB=A0NEK0	Anopheles gambiae	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_48108\|UniProtKB=E9GAW0	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW020498\|UniProtKB=B7Q187	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g213043\|UniProtKB=A7SJ22	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g220027\|UniProtKB=A7SZM2	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG59765\|UniProtKB=B3S6D3	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG55857\|UniProtKB=B3RW21	Trichoplax adhaerens	LDO