PANTHER Gene Information

Gene Symbol(s):

DUX3

Organism:

Homo sapiens

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Gene Name:

Putative double homeobox protein 3

Gene ID:

HGNC:3081

Protein ID:

Q96PT4

Enhancers:

View enhancers for HUMAN|HGNC=3081|UniProtKB=Q96PT4

Genetic Variant Annotation:

Annoq

Persistent Id:

PTN002518933

Alternate Ids:

AAD33597(EMBL-CDS)	AF133130(EMBL)
DUX3(Symbol)	HGNC:3081(HGNC)
74717114(GI)	611443(MIM)
DUX3(Synonym)	DUX3_HUMAN(UniProtKB-ID)
Q9UND2(AltAccession)
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PANTHER Classification

PANTHER Family:	MIX-TYPE HOMEOBOX GENE 1-RELATED (PTHR46123)
PANTHER Subfamily:	DOUBLE HOMEOBOX PROTEIN 1-RELATED (PTHR46123:SF3)
PANTHER GO-slim Molecular Function:	RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process:	regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	homeodomain transcription factor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	RNA polymerase II transcription regulatory region sequence-specific DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete:	regulation of transcription by RNA polymerase II
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000031338.3\|UniProtKB=A0A2I3SFR4	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000046091.1\|UniProtKB=A0A2I3S8R4	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000048334.1\|UniProtKB=A0A2I3T539	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000052669.1\|UniProtKB=A0A2I3SV72	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000042903.1\|UniProtKB=A0A2I3T9X4	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000049578.1\|UniProtKB=A0A2I3RUM0	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000025204.2\|UniProtKB=G3S285	Gorilla gorilla gorilla	O
GORGO\|Ensembl=ENSGGOG00000023520.2\|UniProtKB=G3SIN0	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000060367.1\|UniProtKB=A0A5F8AQS5	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000050221.1\|UniProtKB=A7E3J4	Macaca mulatta	O
MOUSE\|MGI=MGI=1916048\|UniProtKB=Q7TNE6	Mus musculus	O
RAT\|RGD=1311053\|UniProtKB=D3ZTT0	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000050327.1\|UniProtKB=A0A3Q1LRZ0	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000049205.1\|UniProtKB=A0A3Q1LV15	Bos taurus	O
HORSE\|Ensembl=ENSECAG00000037731.2\|UniProtKB=A0A3Q2KLH0	Equus caballus	O
CANLF\|Ensembl=ENSCAFG00845008808.1\|UniProtKB=A0A8I3MZ89	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000029013.2\|UniProtKB=K7E3N5	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000047618.1\|UniProtKB=A0A6I8NF41	Ornithorhynchus anatinus	O
XENLA\|Gene=sia3.S\|UniProtKB=A0A1B4ZDM2	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-480406\|UniProtKB=A0A1B4ZDL5	Xenopus tropicalis	O
XENLA\|Gene=bix1.3.S\|UniProtKB=B7ZQT2	Xenopus laevis	O
XENLA\|Gene=mix-b\|UniProtKB=Q91685	Xenopus laevis	O
XENLA\|Gene=bix1.1.S\|UniProtKB=A0A8J0VJZ4	Xenopus laevis	O
XENLA\|Gene=mixer.S\|UniProtKB=A0A1L8G0Z6	Xenopus laevis	O
XENLA\|Gene=bix1.1.L\|UniProtKB=O93535	Xenopus laevis	O
XENLA\|Gene=bix1.2.S\|UniProtKB=O93534	Xenopus laevis	O
XENLA\|Gene=mixer.L\|UniProtKB=A0A8J0V4P2	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-487318\|UniProtKB=Q4JF53	Xenopus tropicalis	O
XENLA\|Gene=siamois\|UniProtKB=Q91848	Xenopus laevis	O
XENLA\|Gene=sia2.L\|UniProtKB=A0A1B4ZDN7	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-482070\|UniProtKB=A0A1B4ZDM5	Xenopus tropicalis	O
XENLA\|Gene=homeobox100496651-provisional.L\|UniProtKB=A0A1L8FK81	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-22065713\|UniProtKB=A0A6I8S867	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000000457.2\|UniProtKB=H2L479	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-000710-6\|UniProtKB=Q1RM27	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-000710-7\|UniProtKB=A0JPE5	Danio rerio	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_256759\|UniProtKB=E9HC09	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_256751\|UniProtKB=E9HC04	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG178473\|UniProtKB=T1FD80	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG178467\|UniProtKB=T1FD75	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG178476\|UniProtKB=T1FD83	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG178474\|UniProtKB=T1FD81	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG178482\|UniProtKB=T1FD88	helobdella robusta	O