PANTHER Gene Information

Gene Symbol(s):

Dhrs4

Organism:

Mus musculus

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Gene Name:

Dehydrogenase_reductase SDR family member 4

Gene ID:

MGI:90169

Protein ID:

Q99LB2

Persistent Id:

PTN000673567

Alternate Ids:

CR {ECO:0000250\|UniProtKB:Q8WNV7}(Synonym)	MGI:90169(MGI)
BAB18776(EMBL-CDS)	AC159002(EMBL)
DHRS4_MOUSE(UniProtKB-ID)	ENSMUSG00000022210(Ensembl)
ENSMUSP00000022821(Ensembl_PRO)	28200(GeneID)
Q9EQU4(AltAccession)	Dhrs4{ECO:0000312\|MGI:MGI:90169}(Symbol)
NM_001037938(refSeq)	408360290(GI)
ENSMUST00000022821(Ensembl_TRS)	1.1.1.300 {ECO:0000250\|UniProtKB:Q8WNV7}(EC)
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PANTHER Classification

PANTHER Family:	DEHYDROGENASE/REDUCTASE (SDR FAMILY) MEMBER 4 (PTHR43943)
PANTHER Subfamily:	DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 4-RELATED (PTHR43943:SF8)
PANTHER GO-slim Molecular Function:	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	dehydrogenase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	carbonyl reductase (NADPH) activity, 3-keto sterol reductase activity, identical protein binding, all-trans-retinol dehydrogenase (NADP+) activity, oxidoreductase activity, retinal dehydrogenase activity, alcohol dehydrogenase [NAD(P)+] activity, oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
GO BP Complete:	retinal metabolic process
GO CC Complete:	peroxisomal membrane, nucleus, peroxisome, mitochondrion

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Signal Transduction, Peroxisomal protein import, RA biosynthesis pathway, Protein localization, Signaling by Retinoic Acid, Signaling by Nuclear Receptors

Orthologs

ID	Organism	Type
HUMAN\|HGNC=19732\|UniProtKB=P0CG22	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000006184.7\|UniProtKB=H2R3L5	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000025993.2\|UniProtKB=G3RT18	Gorilla gorilla gorilla	O
HUMAN\|HGNC=19731\|UniProtKB=Q6PKH6	Homo sapiens	O
HUMAN\|HGNC=16985\|UniProtKB=Q9BTZ2	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000042451.2\|UniProtKB=A0A2I3SF76	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000015938.3\|UniProtKB=A0A2I2YUQ9	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000007465.4\|UniProtKB=F6R289	Macaca mulatta	LDO
RAT\|RGD=708482\|UniProtKB=Q8VID1	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000017665.6\|UniProtKB=F1MZD5	Bos taurus	LDO
BOVIN\|Gene=DHRS4\|UniProtKB=Q8SPU8	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000002013\|UniProtKB=Q8WNV7	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000025768.4\|UniProtKB=M3X301	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845004249.1\|UniProtKB=A0A8I3MKH3	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000003691.3\|UniProtKB=F7FAH7	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000040799.1\|UniProtKB=A0A6I8NXY9	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010005420.1\|UniProtKB=A0A8V0XNP4	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000008086.3\|UniProtKB=H9GDH6	Anolis carolinensis	LDO
XENLA\|Gene=dhrs4.L\|UniProtKB=Q6DJN9	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-959123\|UniProtKB=A0A8J0SJH9	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000022608.1\|UniProtKB=A0A3B3HF21	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-1498\|UniProtKB=F1Q8N0	Danio rerio	LDO
CIOIN\|Ensembl=ENSCING00000023602.1\|UniProtKB=H2XJL6	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118417901\|UniProtKB=A0A9J7MUL9	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC764565\|UniProtKB=A0A7M7N5S1	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00010063\|UniProtKB=G5EGA6	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00031071\|UniProtKB=A8X8Y7	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00272979\|UniProtKB=A0A2A6C7F3	Pristionchus pacificus	LDO
CAEEL\|WormBase=WBGene00000976\|UniProtKB=O16619	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG24129\|UniProtKB=H8WHB8	Caenorhabditis briggsae	O
DROME\|FlyBase=FBgn0035588\|UniProtKB=Q9VRJ4	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP007475\|UniProtKB=Q7QJE4	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC003118\|UniProtKB=D6WFA2	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC003117\|UniProtKB=D6WFA3	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_316810\|UniProtKB=E9GE27	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_329598\|UniProtKB=E9HH34	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_302551\|UniProtKB=E9GE29	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_241363\|UniProtKB=E9GE28	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_310758\|UniProtKB=E9FVF3	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG70909\|UniProtKB=T1G0E2	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG185211\|UniProtKB=T1FMI5	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g130952\|UniProtKB=A7STD1	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG25681\|UniProtKB=B3RXJ3	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG60225\|UniProtKB=B3S7M7	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG37528\|UniProtKB=B3RV42	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_28844\|UniProtKB=A9V982	Monosiga brevicollis	LDO
PARTE\|EnsemblGenome=GSPATT00018029001\|UniProtKB=A0DKZ5	Paramecium tetraurelia	LDO
CHLRE\|EnsemblGenome=CHLRE_03g191850v5\|UniProtKB=A8IWD2	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00074p00142660\|UniProtKB=W1NMX9	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_64G00360\|UniProtKB=A0A0K9NV16	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma01_g11480\|UniProtKB=A0A804HSX3	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma03_g00940\|UniProtKB=A0A804I739	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_023036mg\|UniProtKB=K3Z916	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3009G219500\|UniProtKB=C5YUZ2	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb294750\|UniProtKB=B6TBX0	Zea mays	O
SORBI\|EnsemblGenome=SORBI_3002G111200\|UniProtKB=C5X487	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb305490\|UniProtKB=A0A804Q628	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os09g0133200\|UniProtKB=Q6K447	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_2g34780v3\|UniProtKB=I1HLI4	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0468870\|UniProtKB=F2E2V8	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS5B02G161900\|UniProtKB=A0A3B6LKE7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5A02G164400\|UniProtKB=A0A3B6KGT8	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS5D02G169300\|UniProtKB=A0A3B6MQ27	Triticum aestivum	LDO
NELNU\|Gene=LOC104606515\|UniProtKB=A0A1U8AQV4	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110788723\|UniProtKB=A0A9R0IHF5	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr01g0007441\|UniProtKB=A0A251VL61	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr11g0499561\|UniProtKB=A0A251TFR7	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C100049900\|UniProtKB=A0A9R1WIQ9	Lactuca sativa	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr12g0552501\|UniProtKB=A0A251SBC4	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr15g0679341\|UniProtKB=A0A251S651	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C700347980\|UniProtKB=A0A9R1V106	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a012350mg\|UniProtKB=A0A022R4X7	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_33626\|UniProtKB=A0A2G2XYE7	Capsicum annuum	O
SOLLC\|EnsemblGenome=Solyc04g014670.3\|UniProtKB=A0A3Q7GRP7	Solanum lycopersicum	O
TOBAC\|Gene=LOC107788737\|UniProtKB=A0A1S3ZNT6	Nicotiana tabacum	O
TOBAC\|Gene=LOC107775270\|UniProtKB=A0A1S3YE47	Nicotiana tabacum	O
CAPAN\|EnsemblGenome=T459_29077\|UniProtKB=A0A1U8EYX0	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400013266\|UniProtKB=M1B0T9	Solanum tuberosum	LDO
TOBAC\|Gene=LOC107823087\|UniProtKB=A0A1S4CVZ1	Nicotiana tabacum	O
TOBAC\|Gene=LOC107798923\|UniProtKB=A0A1S4AL91	Nicotiana tabacum	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_E03957\|UniProtKB=A0A059CA07	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_C03P84080.1\|UniProtKB=A0A078GQG9	Brassica napus	O
BRACM\|EnsemblGenome=Bra020854\|UniProtKB=M4DWG0	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_A09P26600.1\|UniProtKB=A0A078FQE6	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra029476\|UniProtKB=A0A397XX18	Brassica campestris	LDO
ARATH\|TAIR=locus=2135467\|UniProtKB=Q9S9W2	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107905900\|UniProtKB=A0A1U8JCY0	Gossypium hirsutum	O
GOSHI\|Gene=LOC107930299\|UniProtKB=A0A1U8LS75	Gossypium hirsutum	O
GOSHI\|Gene=LOC107924910\|UniProtKB=A0A1U8LCS6	Gossypium hirsutum	O
GOSHI\|Gene=LOC107905675\|UniProtKB=A0A1U8JHS3	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_030334\|UniProtKB=A0A061GHG7	Theobroma cacao	LDO
GOSHI\|Gene=LOC107925101\|UniProtKB=A0A1U8L979	Gossypium hirsutum	O
GOSHI\|Gene=LOC107930440\|UniProtKB=A0A1U8LSR7	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_030333\|UniProtKB=A0A061GI58	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g025259mg\|UniProtKB=A0A067GSH9	Citrus sinensis	O
CITSI\|Gene_ORFName=CISIN_1g025273mg\|UniProtKB=A0A067GFA9	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_011G022400v3\|UniProtKB=A0A2K1YEJ3	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_011G022500v3\|UniProtKB=A0A2K1YEI6	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_09G026500\|UniProtKB=A0A2C9V757	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_16G001800\|UniProtKB=A0A2C9U7N7	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0902850\|UniProtKB=B9RXD8	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_09G008900\|UniProtKB=I1KZX6	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_15G113300\|UniProtKB=C6TLW3	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_17G009400\|UniProtKB=B0M195	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_4g132850\|UniProtKB=G7JKG6	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr04_13470\|UniProtKB=A0A2I4F877	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_1G698530\|UniProtKB=A0A0A0LYF9	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_4G012900\|UniProtKB=M5WH01	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_165154\|UniProtKB=D8QSU5	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_270475\|UniProtKB=D8R221	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c18_20320\|UniProtKB=A9RWW9	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0189s0004\|UniProtKB=A0A2R6W196	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_002420150\|UniProtKB=A0A1Y1I8W9	Klebsormidium nitens	LDO
NITMS\|EnsemblGenome=Nmar_0026\|UniProtKB=A9A517	Nitrosopumilus maritimus	LDO
SACS2\|EnsemblGenome=SSO2500\|UniProtKB=Q97VV6	Sulfolobus solfataricus	LDO
RHOBA\|EnsemblGenome=RB4404\|UniProtKB=Q7USN0	Rhodopirellula baltica	LDO
XANCP\|EnsemblGenome=XCC1057\|UniProtKB=Q8PBR2	Xanthomonas campestris	LDO
SALTY\|EnsemblGenome=STM1675\|UniProtKB=Q8ZP72	Salmonella typhimurium	LDO
ECOLI\|EnsemblGenome=BAE78247\|UniProtKB=P39333	Escherichia coli	LDO
CHLAA\|EnsemblGenome=Caur_1290\|UniProtKB=A9WK67	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO1831\|UniProtKB=Q9RJ37	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO2477\|UniProtKB=Q9L2E2	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv3485c\|UniProtKB=O06348	Mycobacterium tuberculosis	O
DEIRA\|EnsemblGenome=DR_1467\|UniProtKB=Q9RUC2	Deinococcus radiodurans	O
BRADU\|Gene=Q89MY3_BRADU\|UniProtKB=Q89MY3	Bradyrhizobium diazoefficiens	O
BRADU\|Gene=Q89QU6_BRADU\|UniProtKB=Q89QU6	Bradyrhizobium diazoefficiens	O
ECOLI\|EnsemblGenome=BAA16444\|UniProtKB=P0CI31	Escherichia coli	O