PANTHER Gene Information   
Gene Symbol(s): Prpf8
Organism: Mus musculus
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Gene Name: Pre-mRNA-processing-splicing factor 8
Gene ID: MGI:2179381
Protein ID: Q99PV0
Persistent Id: PTN000124573
Alternate Ids:
MGI:2179381(MGI) AAH54103(EMBL-CDS)
A5D6Q4(AltAccession) PRP8_MOUSE(UniProtKB-ID)
115583687(GI) NM_138659(refSeq)
AB047391(EMBL) ENSMUSG00000020850(Ensembl)
Prpf8(Symbol) ENSMUST00000018449(Ensembl_TRS)
ENSMUSP00000018449(Ensembl_PRO) PRP8(Synonym)
192159(GeneID)
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PANTHER Classification
PANTHER Family: PRE-MRNA SPLICING FACTOR PRP8 (PTHR11140)
PANTHER Subfamily: PRE-MRNA-PROCESSING-SPLICING FACTOR 8 (PTHR11140:SF0)  
PANTHER GO-slim Molecular Function: pre-mRNA binding
snRNA binding
PANTHER GO-slim Biological Process: spliceosomal snRNP assembly
PANTHER GO-slim Cellular Component: U5 snRNP
catalytic step 2 spliceosome
PANTHER protein class: RNA splicing factor
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: U6 snRNA binding, U5 snRNA binding, pre-mRNA intronic binding, RNA binding, K63-linked polyubiquitin modification-dependent protein binding, U1 snRNA binding, peptidase activity, U2 snRNA binding, metallopeptidase activity
GO BP Complete: RNA splicing, cellular response to lipopolysaccharide, cellular response to tumor necrosis factor, mRNA processing, spliceosomal tri-snRNP complex assembly, mRNA splicing, via spliceosome
GO CC Complete: nucleus, catalytic step 2 spliceosome, U4/U6 x U5 tri-snRNP complex, U5 snRNP, U2-type catalytic step 1 spliceosome, spliceosomal complex, U2-type catalytic step 2 spliceosome, U2-type precatalytic spliceosome, small nuclear ribonucleoprotein complex, ribonucleoprotein complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Metabolism of RNA, Processing of Capped Intron-Containing Pre-mRNA, mRNA Splicing - Major Pathway, mRNA Splicing - Minor Pathway, mRNA Splicing

Orthologs