PANTHER Gene Information

Gene Symbol(s):

ehs-1

Organism:

Caenorhabditis elegans

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Gene Name:

EHS-1

Gene ID:

WBGene00001224

Protein ID:

Q9BIF4

Persistent Id:

PTN000131276

Alternate Ids:

CCD72519(EMBL-CDS)	WBGene00001224(Ensembl)
NP_001022499(refSeq)	351064231(GI)
WBGene00001224(WormBase)	Q9BIF4_CAEEL(UniProtKB-ID)
BX284602(EMBL)	CE44947(WormBase_PRO)
Q9BIF4(Synonym)	ZK1248.3a(WormBase_TRS)
173985(GeneID)
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PANTHER Classification

PANTHER Family:	EH DOMAIN (PTHR11216)
PANTHER Subfamily:	EPIDERMAL GROWTH FACTOR RECEPTOR PATHWAY SUBSTRATE CLONE 15, ISOFORM A (PTHR11216:SF176)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	endosomal transport endocytosis
PANTHER GO-slim Cellular Component:	plasma membrane protein complex clathrin-coated pit membrane coat
PANTHER protein class:	membrane traffic protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	protein binding
GO BP Complete:	synaptic vesicle endocytosis, endosomal transport, chemical synaptic transmission, endocytosis
GO CC Complete:	presynapse, cytoplasm, clathrin coat of coated pit, synapse, plasma membrane, axon

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Negative regulation of MET activity, Clathrin-mediated endocytosis, Cargo recognition for clathrin-mediated endocytosis, Signal Transduction, EGFR downregulation, Signaling by EGFR, Signaling by MET, Signaling by Receptor Tyrosine Kinases, Vesicle-mediated transport, Membrane Trafficking

Orthologs

ID	Organism	Type
HUMAN\|HGNC=3419\|UniProtKB=P42566	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000000729.7\|UniProtKB=H2PZ06	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000006160.3\|UniProtKB=G3SBN0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000012055.4\|UniProtKB=A0A1D5QSC4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=104583\|UniProtKB=P42567	Mus musculus	LDO
RAT\|RGD=1305550\|UniProtKB=A0A8I5YC99	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000005542.6\|UniProtKB=A5D7I1	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000003872.5\|UniProtKB=A0A5G2QFX7	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000020824.4\|UniProtKB=F6WFQ1	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000027650.4\|UniProtKB=A0A5F5XD12	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845022599.1\|UniProtKB=A0A8I3PMU1	Canis lupus familiaris	LDO
CHICK\|Ensembl=ENSGALG00010024596.1\|UniProtKB=A0A8V0ZYI9	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000007433.4\|UniProtKB=G1KGR7	Anolis carolinensis	LDO
XENLA\|Gene=eps15.S\|UniProtKB=A0A8J0V6Y6	Xenopus laevis	O
XENLA\|Gene=eps15.L\|UniProtKB=A0A8J0V262	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-6070905\|UniProtKB=A0A8J0Q9H0	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000017166.2\|UniProtKB=H2MRU8	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-081104-264\|UniProtKB=F1QIJ6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000009453.1\|UniProtKB=W5MT32	lepisosteus oculatus	LDO
HUMAN\|HGNC=24634\|UniProtKB=Q9UBC2	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000010644.4\|UniProtKB=H2QFP4	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000013623.3\|UniProtKB=G3RCR8	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000000994.4\|UniProtKB=A0A5F8AS86	Macaca mulatta	O
MOUSE\|MGI=MGI=104582\|UniProtKB=Q60902	Mus musculus	O
RAT\|RGD=1565708\|UniProtKB=D3ZJR1	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000009990.6\|UniProtKB=A0A3Q1MMI6	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000013857.5\|UniProtKB=A0A287B5N2	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000019452.4\|UniProtKB=A0A3Q2GSS2	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000013169.6\|UniProtKB=M3WIC2	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845030050.1\|UniProtKB=A0A8I3Q3J5	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000014917.4\|UniProtKB=F7FVU1	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000003714.4\|UniProtKB=A0A6I8N8K0	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010027936.1\|UniProtKB=A0A8V1AID8	Gallus gallus	O
XENLA\|Gene=eps15l1.S\|UniProtKB=A0A8J1LMY0	Xenopus laevis	O
XENLA\|Gene=eps15l1.L\|UniProtKB=A0A8J0UU03	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-959469\|UniProtKB=A0A6I8PPY6	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000018014.2\|UniProtKB=H2MUU0	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000002847.3\|UniProtKB=A0A3B3HT85	Oryzias latipes	O
DANRE\|Gene=eps15l1b\|UniProtKB=A0A8M9P2C3	Danio rerio	O
DANRE\|Gene=eps15l1a\|UniProtKB=A0A8M9PFY2	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000003755.1\|UniProtKB=W5M7Z5	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000009283.3\|UniProtKB=F7BA39	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118414009\|UniProtKB=A0A9J7L012	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC583813\|UniProtKB=A0A7M7PLS9	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC576532\|UniProtKB=A0A7M7PGF0	Strongylocentrotus purpuratus	LDO
CAEBR\|WormBase=WBGene00025548\|UniProtKB=A8WU59	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00097714\|UniProtKB=A0A2A6BZ40	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0035060\|UniProtKB=Q9W111	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP009189\|UniProtKB=A0A1S4H0E4	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC015931\|UniProtKB=D6WTU9	Tribolium castaneum	LDO
HELRO\|EnsemblGenome=HelroG189047\|UniProtKB=T1FQL2	helobdella robusta	LDO
TRIAD\|EnsemblGenome=TriadG58856\|UniProtKB=B3S3V2	Trichoplax adhaerens	LDO
EREGS\|EnsemblGenome=AGOS_AFR103W\|UniProtKB=Q754G7	Eremothecium gossypii	O
CANAL\|CGD=CAL0000177117\|UniProtKB=Q59SR6	Candida albicans	O
ENTH1\|EnsemblGenome=CL6EHI_010300\|UniProtKB=C4LYS7	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_189890\|UniProtKB=C4M720	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0287325\|UniProtKB=Q54KI4	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_148600\|UniProtKB=F0ZBJ2	Dictyostelium purpureum	O
PLAF7\|EnsemblGenome=PF3D7_0322600\|UniProtKB=O97322	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_1025000\|UniProtKB=Q8IJF4	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00026941001\|UniProtKB=A0EH26	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00024421001\|UniProtKB=A0E8S4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00016072001\|UniProtKB=A0DDW4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028681001\|UniProtKB=A0BGH9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00018647001\|UniProtKB=A0DN25	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00016457001\|UniProtKB=A0DF14	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00012344001\|UniProtKB=A0D1A3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00027455001\|UniProtKB=A0EII5	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_23692\|UniProtKB=B8C6I4	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_24639\|UniProtKB=B8CB97	Thalassiosira pseudonana	O