PANTHER Gene Information

Gene Symbol(s):

TXNDC17

Organism:

Homo sapiens

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Gene Name:

Thioredoxin domain-containing protein 17

Gene ID:

HGNC:28218

Protein ID:

Q9BRA2

Enhancers:

View enhancers for HUMAN|HGNC=28218|UniProtKB=Q9BRA2

Genetic Variant Annotation:

Annoq

Persistent Id:

PTN002488230

Alternate Ids:

TXD17_HUMAN(UniProtKB-ID)	74732856(GI)
AAH06405(EMBL-CDS)	AK291963(EMBL)
A8K7E8(AltAccession)	ENSG00000129235(Ensembl)
84817(GeneID)	NM_032731(refSeq)
ENSP00000250101(Ensembl_PRO)	HGNC:28218(HGNC)
14 kDa thioredoxin-related protein(Synonym)	CHEMBL4295935(ChEMBL)
ENST00000250101(Ensembl_TRS)	TXNDC17(Symbol)
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PANTHER Classification

PANTHER Family:	42-9-9 PROTEIN-RELATED (PTHR12452)
PANTHER Subfamily:	THIOREDOXIN DOMAIN-CONTAINING PROTEIN 17 (PTHR12452:SF0)
PANTHER GO-slim Molecular Function:	protein-disulfide reductase activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	cytosol
PANTHER protein class:	transporter

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	peroxidase activity, protein binding, protein-disulfide reductase (NAD(P)H) activity
GO BP Complete:	tumor necrosis factor-mediated signaling pathway, cellular oxidant detoxification
GO CC Complete:	extracellular exosome, cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000008644.4\|UniProtKB=H2QC11	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000003055.3\|UniProtKB=G3QKM5	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000056814.1\|UniProtKB=A0A1D5RCZ3	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1289248\|UniProtKB=Q9CQM5	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000054776.1\|UniProtKB=A0A3Q1MKY2	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000035820.3\|UniProtKB=A0A286ZZM7	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000025006.4\|UniProtKB=A0A9L0RY71	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000024143.4\|UniProtKB=M3WT37	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845002177.1\|UniProtKB=A0A8I3MEZ9	Canis lupus familiaris	LDO
ORNAN\|Ensembl=ENSOANG00000010103.3\|UniProtKB=F7FLG4	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000000462.3\|UniProtKB=A0A6I8NVW7	Ornithorhynchus anatinus	LDO
XENLA\|Gene=txndc17.S\|UniProtKB=Q3KPS0	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-983479\|UniProtKB=A0A8J0R102	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000029099.1\|UniProtKB=A0A3B3INS0	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040801-193\|UniProtKB=Q6DBT3	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000006280.1\|UniProtKB=W5MGS6	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000023649.1\|UniProtKB=H2XSJ3	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118426028\|UniProtKB=A0A9J7LXM2	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC582604\|UniProtKB=A0A7M7RH54	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00022188\|UniProtKB=Q9BL27	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00023866\|UniProtKB=A8WMS2	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00304948\|UniProtKB=A0A8R1V360	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0000318\|UniProtKB=Q9VMQ9	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP009738\|UniProtKB=A0A1S4H2T2	Anopheles gambiae	LDO
DROME\|FlyBase=FBgn0040396\|UniProtKB=Q9U1K7	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP003178\|UniProtKB=Q7QBG9	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC031743\|UniProtKB=A0A139W9N0	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_302246\|UniProtKB=E9HMQ5	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG186220\|UniProtKB=T1FNU0	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g165587\|UniProtKB=A7S2D0	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG61314\|UniProtKB=B3SAM7	Trichoplax adhaerens	LDO
EMENI\|EnsemblGenome=ANIA_08630\|UniProtKB=Q5ASV0	Emericella nidulans	LDO
SCLS1\|EnsemblGenome=SS1G_10109\|UniProtKB=A7EXP4	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_07896\|UniProtKB=Q0UK18	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC21C3.12c\|UniProtKB=Q9P7L1	Schizosaccharomyces pombe	LDO
CRYNJ\|EnsemblGenome=CNL05845\|UniProtKB=A0A0S2M6B1	Cryptococcus neoformans	O
CRYNJ\|EnsemblGenome=CNL06140\|UniProtKB=Q5K8C9	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_02768\|UniProtKB=A0A0D1E0Q0	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_06267\|UniProtKB=E3K7L1	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_86770\|UniProtKB=F4NYK8	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0272418\|UniProtKB=B0G106	Dictyostelium discoideum	LDO
PARTE\|EnsemblGenome=GSPATT00036691001\|UniProtKB=A0CAU3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00023736001\|UniProtKB=A0E6U1	Paramecium tetraurelia	LDO
PHYRM\|Gene=H3GSJ7_PHYRM\|UniProtKB=H3GSJ7	Phytophthora ramorum	O
PHYRM\|Gene=H3GSJ0_PHYRM\|UniProtKB=H3GSJ0	Phytophthora ramorum	O
PHYRM\|Gene=H3GSJ1_PHYRM\|UniProtKB=H3GSJ1	Phytophthora ramorum	LDO
PHYRM\|Gene=H3GSJ2_PHYRM\|UniProtKB=H3GSJ2	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_12g549500v5\|UniProtKB=A0A2K3D696	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_07g315100v5\|UniProtKB=A0A2K3DIN0	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00022p00212550\|UniProtKB=W1PVC3	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_246G00270\|UniProtKB=A0A0K9PJ26	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma04_g01420\|UniProtKB=A0A804IJU0	Musa acuminata subsp. malaccensis	LDO
SORBI\|EnsemblGenome=SORBI_3010G132100\|UniProtKB=C5Z1N7	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb381670\|UniProtKB=B8A1M2	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os06g0320000\|UniProtKB=Q5Z9Z3	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_4g23300v3\|UniProtKB=I1IMT0	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.7HG0675390\|UniProtKB=F2DHB9	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS7D02G226900\|UniProtKB=A0A3B6TP00	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7A02G227500\|UniProtKB=A0A3B6RH73	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS7B02G192000\|UniProtKB=A0A3B6SH88	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_031405\|UniProtKB=A0A1U8ASN9	Nelumbo nucifera	LDO
NELNU\|Gene=LOC104597520\|UniProtKB=A0A1U7ZUU9	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110774941\|UniProtKB=A0A9R0HRA7	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr01g0026931\|UniProtKB=A0A251VPX2	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C800392260\|UniProtKB=A0A9R1UR63	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a016170mg\|UniProtKB=A0A022QRI9	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_14585\|UniProtKB=A0A2G2ZHV2	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_33244\|UniProtKB=A0A2G2XZE0	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_33072\|UniProtKB=A0A1U8E4S2	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400026375\|UniProtKB=M1CHX0	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc10g037980.2\|UniProtKB=A0A3Q7IET1	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107797859\|UniProtKB=A0A1S4AHY5	Nicotiana tabacum	O
TOBAC\|Gene=LOC107789030\|UniProtKB=A0A1S3ZPK1	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi13g02522\|UniProtKB=D7T2W1	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_G03402\|UniProtKB=A0A059BIT3	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_A06P48230.1\|UniProtKB=A0A078GBC7	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra033645\|UniProtKB=M4EXV6	Brassica campestris	LDO
ARATH\|TAIR=locus=2160021\|UniProtKB=Q9FMN4	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107889220\|UniProtKB=A0A1U8HYN5	Gossypium hirsutum	O
GOSHI\|Gene=LOC107900008\|UniProtKB=A0A1U8IT56	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_005930\|UniProtKB=A0A061DVN1	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g032841mg\|UniProtKB=A0A067GV33	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_001G225500v3\|UniProtKB=A9PBT3	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_10G148300\|UniProtKB=A0A2C9V6J4	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1526930\|UniProtKB=B9RHH6	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_08G152300\|UniProtKB=K7L6V9	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_15G271700\|UniProtKB=C6SWX2	Glycine max	LDO
SOYBN\|EnsemblGenome=GLYMA_08G151500\|UniProtKB=I1KTJ7	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_3g027090\|UniProtKB=G7J1S6	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr09_07170\|UniProtKB=A0A2I4G2W9	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_3G701560\|UniProtKB=A0A0A0LEX6	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_2G007200\|UniProtKB=M5XL63	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_132775\|UniProtKB=D8T659	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_134020\|UniProtKB=D8T7U3	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c1_3150\|UniProtKB=A0A7I4BSN1	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0028s0130\|UniProtKB=A0A2R6X9Q7	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000730250\|UniProtKB=A0A1Y1HZA2	Klebsormidium nitens	LDO