PANTHER Gene Information

Gene Symbol(s):

Hint2

Organism:

Mus musculus

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Gene Name:

Adenosine 5'-monophosphoramidase HINT2

Gene ID:

MGI:1916167

Protein ID:

Q9D0S9

Persistent Id:

PTN000557781

Alternate Ids:

68917(GeneID)	NM_026871(refSeq)
HINT-3 {ECO:0000250\|UniProtKB:Q9BX68}(Synonym)	ENSMUSP00000030192(Ensembl_PRO)
ENSMUST00000030192(Ensembl_TRS)	Hint2{ECO:0000312\|MGI:MGI:1916167}(Symbol)
HINT2_MOUSE(UniProtKB-ID)	MGI:1916167(MGI)
AK004497(EMBL)	3.9.1.- {ECO:0000250\|UniProtKB:Q9BX68}(EC)
ENSMUSG00000028470(Ensembl)	AAK94774(EMBL-CDS)
51701614(GI)
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PANTHER Classification

PANTHER Family:	HISTIDINE TRIAD HIT PROTEIN (PTHR23089)
PANTHER Subfamily:	ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT2 (PTHR23089:SF18)
PANTHER GO-slim Molecular Function:	hydrolase activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	mitochondrion
PANTHER protein class:	nucleotide phosphatase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	nucleotide binding, adenosine 5'-monophosphoramidase activity, hydrolase activity
GO BP Complete:	negative regulation of peptidyl-lysine acetylation, apoptotic process, lipid catabolic process, steroid biosynthetic process
GO CC Complete:	cytoplasm, mitochondrial matrix, mitochondrion

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Signaling by Rho GTPases, Signal Transduction, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, RHO GTPase cycle, RHOD GTPase cycle

Orthologs

ID	Organism	Type
HUMAN\|HGNC=18344\|UniProtKB=Q9BX68	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000020923.5\|UniProtKB=H2QX91	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000011265.3\|UniProtKB=G3R6M3	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000016337.4\|UniProtKB=F7GRL0	Macaca mulatta	LDO
RAT\|RGD=1308910\|UniProtKB=D4AB01	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000011444\|UniProtKB=Q8SQ21	Bos taurus	LDO
HORSE\|Ensembl=ENSECAG00000000037.4\|UniProtKB=A0A9L0R5T6	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000012755.4\|UniProtKB=M3WHJ0	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845010022.1\|UniProtKB=A0A8I3NC75	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000006947.3\|UniProtKB=F6RG00	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000040371.1\|UniProtKB=A0A6I8NVQ2	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010009594.1\|UniProtKB=A0A8V0Y2M6	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000034720.1\|UniProtKB=A0A803TNT0	Anolis carolinensis	LDO
XENLA\|Gene=hint2.S\|UniProtKB=A0A310TQF6	Xenopus laevis	LDO
XENTR\|Ensembl=ENSXETG00000042319\|UniProtKB=A0A803JAB9	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000001235.2\|UniProtKB=H2L6R2	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-070410-139\|UniProtKB=A3KP93	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000011981.1\|UniProtKB=W5N276	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000011420.2\|UniProtKB=F7AX27	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118406775\|UniProtKB=A0A9J7HP70	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC579236\|UniProtKB=A0A7M7P0D9	Strongylocentrotus purpuratus	LDO
IXOSC\|EnsemblGenome=ISCW011268\|UniProtKB=A0A1S4LAS5	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g162262\|UniProtKB=A7RSL2	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG32988\|UniProtKB=B3SC44	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_23586\|UniProtKB=A9UTV8	Monosiga brevicollis	O
DICDI\|dictyBase=DDB_G0289391\|UniProtKB=Q23921	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0289439\|UniProtKB=Q54HJ0	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_77557\|UniProtKB=F0ZGZ0	Dictyostelium purpureum	O
PLAF7\|EnsemblGenome=PF3D7_0817500\|UniProtKB=Q7K6B1	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00035927001\|UniProtKB=A0C7N0	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00032434001\|UniProtKB=A0BUI5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028811001\|UniProtKB=A0BGV9	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_31751\|UniProtKB=B8BVT6	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_30979\|UniProtKB=B8BR19	Thalassiosira pseudonana	O
PHYRM\|Gene=H3G7L6_PHYRM\|UniProtKB=H3G7L6	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_06g273000v5\|UniProtKB=A8HVN9	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00062p00187560\|UniProtKB=U5DGX8	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_381G00110\|UniProtKB=A0A0K9P546	Zostera marina	O
MUSAM\|EnsemblGenome=Ma07_g03630\|UniProtKB=A0A804JRS4	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_007363mg\|UniProtKB=K3XZK2	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3010G221600\|UniProtKB=A0A194YKQ4	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb274290\|UniProtKB=B6UAW2	Zea mays	O
ORYSJ\|EnsemblGenome=Os06g0667500\|UniProtKB=Q0DA95	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_1g32219v3\|UniProtKB=A0A0Q3H3A5	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.7HG0737490\|UniProtKB=F2DVF5	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS7B02G376200\|UniProtKB=A0A3B6SRB3	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7A02G474600\|UniProtKB=A0A3B6RLU3	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7D02G461600\|UniProtKB=A0A3B6TQE5	Triticum aestivum	O
NELNU\|Gene_ORFName=HUJ06_002204\|UniProtKB=A0A1U8A6L7	Nelumbo nucifera	O
HELAN\|EnsemblGenome=HanXRQr2_Chr14g0649721\|UniProtKB=A0A251SIB5	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C200072630\|UniProtKB=A0A9R1XRM3	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a014698mg\|UniProtKB=A0A022QR91	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a020861mg\|UniProtKB=A0A022PTW8	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_04945\|UniProtKB=A0A1U8FU10	Capsicum annuum	O
SOLLC\|EnsemblGenome=Solyc02g068700.3\|UniProtKB=A0A3Q7F0Z5	Solanum lycopersicum	O
TOBAC\|Gene=LOC107811311\|UniProtKB=A0A1S4BS33	Nicotiana tabacum	O
TOBAC\|Gene=LOC107812415\|UniProtKB=A0A1S4BVU4	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi01g00132\|UniProtKB=F6HF59	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_E04251\|UniProtKB=A0A059CAW8	Eucalyptus grandis	O
BRACM\|EnsemblGenome=Bra014904\|UniProtKB=M4DEI3	Brassica campestris	O
ARATH\|TAIR=locus=2029559\|UniProtKB=Q8GYJ9	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107960009\|UniProtKB=A0A1U8PKH7	Gossypium hirsutum	O
GOSHI\|Gene=LOC107936468\|UniProtKB=A0A1U8MD26	Gossypium hirsutum	O
GOSHI\|Gene=LOC107945221\|UniProtKB=A0A1U8N683	Gossypium hirsutum	O
GOSHI\|Gene=LOC107928675\|UniProtKB=A0A1U8LLD6	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_006052\|UniProtKB=A0A061DXU8	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g029617mg\|UniProtKB=A0A067GPU6	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_015G124700v3\|UniProtKB=A0A2K1XM08	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_16G056900\|UniProtKB=A0A2C9U9A3	Manihot esculenta	O
SOYBN\|EnsemblGenome=GLYMA_15G161000\|UniProtKB=I1MGX8	Glycine max	O
MEDTR\|EnsemblGenome=MTR_4g084190\|UniProtKB=A0A072UM23	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr03_09310\|UniProtKB=A0A2I4G0B5	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_1G701380\|UniProtKB=A0A0A0M163	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_4G113300\|UniProtKB=A0A251PJ05	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_94999\|UniProtKB=D8RJL8	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_95126\|UniProtKB=D8RJR6	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_77650\|UniProtKB=D8QU02	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_76264\|UniProtKB=D8QTW1	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c3_13210\|UniProtKB=A0A2K1KUC9	Physcomitrella patens	O
AMBTC\|EnsemblGenome=AMTR_s00101p00042720\|UniProtKB=W1NTX5	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_121G00160\|UniProtKB=A0A0K9Q2X0	Zostera marina	O
MUSAM\|EnsemblGenome=Ma06_g33780\|UniProtKB=A0A804JND9	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma01_g22880\|UniProtKB=A0A804HXB6	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_003153mg\|UniProtKB=K3XMN0	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3003G332100\|UniProtKB=C5XN54	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb150020\|UniProtKB=A0A804NBW3	Zea mays	O
SETIT\|EnsemblGenome=SETIT_038024mg\|UniProtKB=K4AGL7	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3001G388600\|UniProtKB=C5X1S5	Sorghum bicolor	O
MAIZE\|Gene=ZBP14\|UniProtKB=P42856	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb015330\|UniProtKB=B6SJF7	Zea mays	O
ORYSJ\|EnsemblGenome=Os03g0322500\|UniProtKB=Q10M57	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_1g63860v3\|UniProtKB=I1H603	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.4HG0380240\|UniProtKB=F2DDF2	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS4D02G178000\|UniProtKB=A0A3B6JKD5	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4A02G128600\|UniProtKB=W5E2R7	Triticum aestivum	O
NELNU\|Gene=LOC104593485\|UniProtKB=A0A1U7ZJ85	Nelumbo nucifera	O
SPIOL\|Gene=LOC110777868\|UniProtKB=A0A9R0HYE0	Spinacia oleracea	O
SPIOL\|Gene=LOC110804048\|UniProtKB=A0A9R0JCH7	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr10g0435971\|UniProtKB=A0A251TLD7	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr17g0786951\|UniProtKB=A0A251RMG0	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C900467800\|UniProtKB=A0A9R1UGE2	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a015436mg\|UniProtKB=A0A022R4Y7	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_18898\|UniProtKB=A0A2G2Z064	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_25502\|UniProtKB=A0A1U8EEW8	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_26375\|UniProtKB=A0A2G2YNT7	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400028208\|UniProtKB=M1CQE7	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc10g081310.2\|UniProtKB=A0A3Q7IL99	Solanum lycopersicum	O
TOBAC\|Gene=LOC107773830\|UniProtKB=A0A1S3Y9P0	Nicotiana tabacum	O
TOBAC\|Gene=LOC107800041\|UniProtKB=A0A1S4AQ32	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi08g00059\|UniProtKB=F6HMU5	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_K01707\|UniProtKB=A0A059A2T3	Eucalyptus grandis	O
BRANA\|Gene_ORFName=GSBRNA2T00050856001\|UniProtKB=A0A078H3S2	Brassica napus	O
BRACM\|EnsemblGenome=Bra003243\|UniProtKB=M4CGB0	Brassica campestris	O
BRANA\|EnsemblGenome=GSBRNA2T00155949001\|UniProtKB=A0A078C5F6	Brassica napus	O
BRACM\|EnsemblGenome=Bra007249\|UniProtKB=M4CSQ7	Brassica campestris	O
BRANA\|EnsemblGenome=GSBRNA2T00063616001\|UniProtKB=A0A078JP05	Brassica napus	O
BRACM\|EnsemblGenome=Bra014689\|UniProtKB=M4DDX0	Brassica campestris	O
ARATH\|TAIR=locus=2102554\|UniProtKB=Q8GUN2	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107935518\|UniProtKB=A0A1U8M9V0	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_023785\|UniProtKB=A0A061EWE6	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g031773mg\|UniProtKB=A0A067EQG0	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_016G023700v3\|UniProtKB=B9IHG3	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_08G065600\|UniProtKB=A0A2C9VDZ3	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0672450\|UniProtKB=B9S3L7	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_19G123100\|UniProtKB=K7MY10	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_19G067800\|UniProtKB=I1N7B1	Glycine max	O
MEDTR\|EnsemblGenome=MTR_6g026810\|UniProtKB=G7KP65	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr04_06310\|UniProtKB=A0A2I4ETL3	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_3G814350\|UniProtKB=A0A0A0LC24	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_7G023000\|UniProtKB=M5VRG6	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_121527\|UniProtKB=D8SNZ8	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_446557\|UniProtKB=D8SSE1	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c2_22310\|UniProtKB=A0A7I4D1P6	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0066s0117\|UniProtKB=A0A2R6WQL8	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_000320360\|UniProtKB=A0A1Y1HUK9	Klebsormidium nitens	O