PANTHER Gene Information

Gene Symbol(s):

GPN1

Organism:

Homo sapiens

View Gene in Tree


Tree	Reduced Tree

Gene Name:

GPN-loop GTPase 1

Gene ID:

HGNC:17030

Protein ID:

Q9HCN4

Enhancers:

View enhancers for HUMAN|HGNC=17030|UniProtKB=Q9HCN4

Genetic Variant Annotation:

Annoq

Persistent Id:

PTN002501586

Alternate Ids:

194385160(GI)	AB044661(EMBL)
3.6.5.- {ECO:0000269\|PubMed:11058119, ECO:0000269\|PubMed:21768307}(EC)	11321(GeneID)
611479(MIM)	HGNC:17030(HGNC)
B4DQM4(AltAccession)	MBD2-interacting protein(Synonym)
AAH07451(EMBL-CDS)	GPN1{ECO:0000303\|PubMed:20855544,ECO:0000312\|HGNC:HGNC:17030}(Symbol)
GPN1_HUMAN(UniProtKB-ID)	ENSG00000198522(Ensembl)
Show All

PANTHER Classification

PANTHER Family:	XPA-BINDING PROTEIN 1-RELATED (PTHR21231)
PANTHER Subfamily:	GPN-LOOP GTPASE 1 (PTHR21231:SF8)
PANTHER GO-slim Molecular Function:	GTPase activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	small GTPase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	GTP binding, ATP hydrolysis activity, protein binding, GTPase activity
GO BP Complete:	-
GO CC Complete:	mitochondrion, cytosol, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000011776.4\|UniProtKB=H2QHN7	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000015285.3\|UniProtKB=G3RH01	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000019745.4\|UniProtKB=F7AXX0	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1921504\|UniProtKB=Q8VCE2	Mus musculus	LDO
RAT\|RGD=1589985\|UniProtKB=A0A8I6ATM7	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000003904\|UniProtKB=A4FUD1	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000008546.4\|UniProtKB=F1SEE2	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000009579.4\|UniProtKB=A0A9L0SF73	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000030425.4\|UniProtKB=A0A337SPF6	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845009100.1\|UniProtKB=A0A8I3N1F0	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00845009711.1\|UniProtKB=A0A8I3NP48	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00845008741.1\|UniProtKB=A0A8I3NAB3	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000015592.3\|UniProtKB=F6ZUF6	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000021529.2\|UniProtKB=A0A6I8NB86	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010008790.1\|UniProtKB=A0A8V0Y3H2	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000008974.4\|UniProtKB=H9GEN5	Anolis carolinensis	LDO
XENLA\|Gene=gpn1.L\|UniProtKB=Q3KQ86	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-6454885\|UniProtKB=A4IH64	Xenopus tropicalis	LDO
DANRE\|ZFIN=ZDB-GENE-040801-154\|UniProtKB=Q6DC83	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000015949.1\|UniProtKB=W5NG82	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000023847.1\|UniProtKB=H2XVC3	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118420872\|UniProtKB=A0A9J7LJ06	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC593577\|UniProtKB=A0A7M7SUY9	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00001661\|UniProtKB=P46577	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG21182\|UniProtKB=A8XZN8	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00101954\|UniProtKB=A0A454XQ64	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0040346\|UniProtKB=Q9V3R3	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP010314\|UniProtKB=Q7PLX5	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC015364\|UniProtKB=D2A4G3	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_217322\|UniProtKB=E9HCV1	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW016116\|UniProtKB=B7P173	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG69993\|UniProtKB=T1G012	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g225255\|UniProtKB=A7TCI4	Nematostella vectensis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g162906\|UniProtKB=A7RUM5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g5663\|UniProtKB=A7T927	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG19709\|UniProtKB=B3RIJ5	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_34382\|UniProtKB=A9VBA3	Monosiga brevicollis	LDO
YEAST\|SGD=S000003833\|UniProtKB=P47122	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AFR428C\|UniProtKB=Q753Q6	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000183311\|UniProtKB=A0A1D8PR52	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E21626g\|UniProtKB=Q6C525	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_05536\|UniProtKB=Q5B1P4	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_4G11820\|UniProtKB=Q4WQ74	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU04507\|UniProtKB=Q7RY56	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_06725\|UniProtKB=A7EN26	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_07075\|UniProtKB=Q0UMD9	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC119.15\|UniProtKB=O42906	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_04531\|UniProtKB=B6K727	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CND04790\|UniProtKB=Q5KHZ2	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_11665\|UniProtKB=A0A0D1E2B9	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_21323\|UniProtKB=H6QR56	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_20815\|UniProtKB=F4PBU2	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_009950\|UniProtKB=C4M0R0	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0293220\|UniProtKB=Q54C25	Dictyostelium discoideum	LDO
LEIMA\|EnsemblGenome=LMJF_13_1280\|UniProtKB=Q4QG26	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb11.02.1040\|UniProtKB=Q386F6	Trypanosoma brucei	LDO
GIAIC\|EnsemblGenome=GL50803_15164\|UniProtKB=A8B4B6	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_071390\|UniProtKB=A2D842	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_1201500\|UniProtKB=Q8I630	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00010190001\|UniProtKB=A0BYR6	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_bd2107\|UniProtKB=B8LEX5	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3G7E6_PHYRM\|UniProtKB=H3G7E6	Phytophthora ramorum	LDO
PHYRM\|Gene=H3G7P8_PHYRM\|UniProtKB=H3G7P8	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_06g267150v5\|UniProtKB=A0A2K3DN25	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00003p00235130\|UniProtKB=W1P8J9	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_65G00320\|UniProtKB=A0A0K9NUS8	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_2G01420\|UniProtKB=A0A0K9PAZ5	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_307G00280\|UniProtKB=A0A0K9PA99	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma11_g14630\|UniProtKB=A0A804L7W5	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma02_g00330\|UniProtKB=A0A804HXR5	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_035985mg\|UniProtKB=K4AAS8	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3001G515100\|UniProtKB=C5WZ18	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb395880\|UniProtKB=K7VIW2	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os03g0312600\|UniProtKB=Q10MD7	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_4g36230v3\|UniProtKB=I1IS74	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0070080\|UniProtKB=A0A8I6WS56	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS1A02G306100\|UniProtKB=A0A3B5Y380	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1B02G316800\|UniProtKB=A0A3B5Z1Q3	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1D02G305800\|UniProtKB=A0A3B5ZY50	Triticum aestivum	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.4HG0381580\|UniProtKB=A0A8I6XCN9	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS4B02G180800\|UniProtKB=A0A3B6ITT1	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4D02G182300\|UniProtKB=A0A3B6JIN9	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS4A02G123700\|UniProtKB=A0A3B6HRF3	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_011926\|UniProtKB=A0A1U8ANZ5	Nelumbo nucifera	O
NELNU\|Gene_ORFName=HUJ06_008950\|UniProtKB=A0A1U8AAW6	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110803648\|UniProtKB=A0A9R0KAN8	Spinacia oleracea	LDO
SPIOL\|Gene=LOC110786076\|UniProtKB=A0A9R0IBM0	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HannXRQ_Chr08g0212681\|UniProtKB=A0A251U3A0	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr10g0461371\|UniProtKB=A0A251TQN6	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr05g0218151\|UniProtKB=A0A251RUG2	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C900480140\|UniProtKB=A0A9R1WP74	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a007883mg\|UniProtKB=A0A022PYJ8	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_00256\|UniProtKB=A0A1U8G689	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400012333\|UniProtKB=M1AWX4	Solanum tuberosum	LDO
TOBAC\|Gene=LOC107817045\|UniProtKB=A0A1S4CAP4	Nicotiana tabacum	O
TOBAC\|Gene=LOC107808025\|UniProtKB=A0A1S4BGJ3	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi05g01784\|UniProtKB=D7SYI9	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_K01628\|UniProtKB=A0A059A162	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00037386001\|UniProtKB=A0A078GS32	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra020871\|UniProtKB=M4DWH7	Brassica campestris	O
BRACM\|EnsemblGenome=Bra013562\|UniProtKB=M4DAQ2	Brassica campestris	LDO
ARATH\|TAIR=locus=2119093\|UniProtKB=Q8W586	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107929110\|UniProtKB=A0A1U8LR94	Gossypium hirsutum	O
GOSHI\|Gene=LOC107928542\|UniProtKB=A0A1U8LL00	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_020790\|UniProtKB=A0A061EMM5	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g014354mg\|UniProtKB=A0A067G8Y7	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_010G148000v3\|UniProtKB=B9HX45	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_008G103000v3\|UniProtKB=B9HIL7	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_08G074300\|UniProtKB=A0A2C9VFH9	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_09G084300\|UniProtKB=A0A2C9V907	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1775060\|UniProtKB=B9REL8	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_17G035700\|UniProtKB=I1MRT2	Glycine max	LDO
SOYBN\|EnsemblGenome=GLYMA_07G237800\|UniProtKB=I1KMP4	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g100240\|UniProtKB=G7IEN9	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr12_10040\|UniProtKB=A0A2I4F1W7	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_2G076540\|UniProtKB=A0A0A0LHM2	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_1G114400\|UniProtKB=M5XCT4	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_3016\|UniProtKB=D8SNI4	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c8_16870\|UniProtKB=A9SSV0	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0080s0030\|UniProtKB=A0A2R6WKL7	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_001170150\|UniProtKB=A0A1Y1I0C2	Klebsormidium nitens	LDO
NITMS\|EnsemblGenome=Nmar_0042\|UniProtKB=A9A533	Nitrosopumilus maritimus	LDO
KORCO\|EnsemblGenome=Kcr_1388\|UniProtKB=B1L6Q5	Korarchaeum cryptofilum	LDO
SACS2\|EnsemblGenome=SSO1046\|UniProtKB=Q97Z85	Sulfolobus solfataricus	LDO
PYRAE\|EnsemblGenome=PAE3333\|UniProtKB=Q8ZTB6	Pyrobaculum aerophilum	LDO
THEKO\|EnsemblGenome=TK0951\|UniProtKB=Q5JIA1	Thermococcus kodakaraensis	LDO