PANTHER Gene Information

Gene Symbol(s):

Higd1a

Organism:

Mus musculus

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Gene Name:

HIG1 domain family member 1A, mitochondrial

Gene ID:

MGI:1930666

Protein ID:

Q9JLR9

Persistent Id:

PTN000265851

Alternate Ids:

AK018360(EMBL)	76363183(GI)
ENSMUST00000213124(Ensembl_TRS)	NP_062788(refSeq)
56295(GeneID)	HIG1A_MOUSE(UniProtKB-ID)
ENSMUSP00000150726(Ensembl_PRO)	Hig1(Synonym)
BAB31176(EMBL-CDS)	MGI:1930666(MGI)
ENSMUSG00000038412(Ensembl)	Higd1a(Symbol)
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PANTHER Classification

PANTHER Family:	HYPOXIA-INDUCBILE GENE 1 HIG1 -RELATED (PTHR12297)
PANTHER Subfamily:	HIG1 DOMAIN FAMILY MEMBER 1A, MITOCHONDRIAL (PTHR12297:SF5)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	mitochondrion organization protein-containing complex assembly
PANTHER GO-slim Cellular Component:	mitochondrion
PANTHER protein class:	scaffold/adaptor protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	molecular_function
GO BP Complete:	negative regulation of release of cytochrome c from mitochondria, negative regulation of apoptotic process, cellular response to hypoxia, mitochondrial respirasome assembly, positive regulation of protein serine/threonine kinase activity, cellular response to glucose starvation
GO CC Complete:	nucleus, mitochondrion, membrane, protein-containing complex, mitochondrial inner membrane, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000050870.1\|UniProtKB=A0A2I3SCP6	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000038002.1\|UniProtKB=A0A2I2YME8	Gorilla gorilla gorilla	O
PANTR\|Ensembl=ENSPTRG00000048485.1\|UniProtKB=A0A2I3THH1	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000024036.2\|UniProtKB=G3RY47	Gorilla gorilla gorilla	O
HUMAN\|HGNC=29527\|UniProtKB=Q9Y241	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000014802.6\|UniProtKB=H2RFB3	Pan troglodytes	LDO
PANTR\|Ensembl=ENSPTRG00000052178.1\|UniProtKB=A0A2I3RVC4	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000052859.1\|UniProtKB=A0A2I3TV60	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000041459.1\|UniProtKB=A0A2I2Z1S7	Gorilla gorilla gorilla	O
GORGO\|Ensembl=ENSGGOG00000016759.3\|UniProtKB=A0A2I2Z8P0	Gorilla gorilla gorilla	LDO
RAT\|RGD=15003249\|UniProtKB=A0A8I6AFI4	Rattus norvegicus	O
RAT\|RGD=620215\|UniProtKB=Q8VH49	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000038640.3\|UniProtKB=G3X833	Bos taurus	O
FELCA\|Ensembl=ENSFCAG00000039759.3\|UniProtKB=A0A2I2UQ51	Felis catus	O
BOVIN\|Ensembl=ENSBTAG00000046941.2\|UniProtKB=A0A3Q1N117	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000045592.2\|UniProtKB=E1BL48	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000054433.1\|UniProtKB=A0A3Q1LR84	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000054799.1\|UniProtKB=A0A3Q1M1W6	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000035021.4\|UniProtKB=A0A3Q1M2Q9	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000034676.4\|UniProtKB=Q1LZ70	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00005044401.1\|UniProtKB=F1SRE7	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000037832.1\|UniProtKB=A0A3Q2H5E3	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000010978.3\|UniProtKB=A0A9L0S9D5	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000032676.2\|UniProtKB=A0A2I2URN4	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845017928.1\|UniProtKB=A0A8I3P1Q5	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00845003536.1\|UniProtKB=A0A8I3MRG3	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00845021078.1\|UniProtKB=A0A8I3PAZ6	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000037806.1\|UniProtKB=A0A5F8GWC3	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000036608.1\|UniProtKB=A0A5F8GRA1	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000025420.2\|UniProtKB=F6WI92	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000013605.3\|UniProtKB=F6VVJ0	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000025419.2\|UniProtKB=F6VVI4	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000038143.1\|UniProtKB=A0A6I8N4N7	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010027707.1\|UniProtKB=A0A8V1AA24	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000006500.3\|UniProtKB=A0A803T4H3	Anolis carolinensis	LDO
XENLA\|Gene=higd1c.L\|UniProtKB=Q6NRS0	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-5935687\|UniProtKB=Q5M8D7	Xenopus tropicalis	O
XENLA\|Gene=higd1a.L\|UniProtKB=Q6DJP8	Xenopus laevis	O
XENLA\|Gene=higd1a.S\|UniProtKB=Q7ZZZ3	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-974391\|UniProtKB=Q5XH86	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000024205.1\|UniProtKB=A0A3B3ICC3	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030826-15\|UniProtKB=Q7ZZZ4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000009418.1\|UniProtKB=W5MSY1	lepisosteus oculatus	LDO
LEPOC\|Ensembl=ENSLOCG00000003806.1\|UniProtKB=W5M831	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000018302.1\|UniProtKB=H2XS33	Ciona intestinalis	LDO
STRPU\|EnsemblGenome=LOC581354\|UniProtKB=A0A7M7REY4	Strongylocentrotus purpuratus	LDO
DROME\|FlyBase=FBgn0037890\|UniProtKB=A0A0B4K6E6	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0033519\|UniProtKB=A0A0B4KEI1	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP010716\|UniProtKB=Q7QE07	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC003997\|UniProtKB=D6WIG9	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_231437\|UniProtKB=E9H6U7	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW010981\|UniProtKB=B7Q7J4	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG83602\|UniProtKB=T1G581	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g88314\|UniProtKB=A7RP71	Nematostella vectensis	LDO
YEAST\|SGD=S000004492\|UniProtKB=Q03713	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AER310W\|UniProtKB=Q756G1	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000199655\|UniProtKB=Q59N74	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_C16456g\|UniProtKB=Q6CBQ8	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_03831\|UniProtKB=Q5B6J9	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_4G08130\|UniProtKB=Q4WP59	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU02451\|UniProtKB=Q7S455	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_13108\|UniProtKB=A7F679	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_01023\|UniProtKB=Q0V4P1	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC25B8.07c\|UniProtKB=Q9UTB1	Schizosaccharomyces pombe	LDO
CRYNJ\|EnsemblGenome=CNC04010\|UniProtKB=Q5KK74	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_00057\|UniProtKB=Q4PIK6	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_16683\|UniProtKB=E3L282	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_89273\|UniProtKB=F4P445	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0278571\|UniProtKB=Q54XU9	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_45921\|UniProtKB=F0ZCK8	Dictyostelium purpureum	LDO
PHYRM\|Gene=H3H004_PHYRM\|UniProtKB=H3H004	Phytophthora ramorum	LDO
AMBTC\|EnsemblGenome=AMTR_s00001p00271420\|UniProtKB=W1NMU6	Amborella trichopoda	O
AMBTC\|EnsemblGenome=AMTR_s00040p00125400\|UniProtKB=W1PYA8	Amborella trichopoda	O
AMBTC\|EnsemblGenome=AMTR_s00088p00076720\|UniProtKB=W1NW76	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_44G01620\|UniProtKB=A0A0K9P1A6	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma06_g38010\|UniProtKB=A0A804JQ11	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_033240mg\|UniProtKB=K4A2Y8	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3002G187500\|UniProtKB=C5XBE1	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb311470\|UniProtKB=B6SR83	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os09g0375900\|UniProtKB=Q6H5G3	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_4g29300v3\|UniProtKB=I1IPT6	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0477470\|UniProtKB=F2DZK2	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS5A02G187200\|UniProtKB=A0A3B6KF59	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5B02G196700\|UniProtKB=W5FKT5	Triticum aestivum	LDO
NELNU\|Gene=LOC104595330\|UniProtKB=A0A1U7ZM61	Nelumbo nucifera	O
NELNU\|Gene=LOC104607917\|UniProtKB=A0A1U8B6W6	Nelumbo nucifera	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr07g0307751\|UniProtKB=A0A251T6M8	Helianthus annuus	O
HELAN\|Gene_ORFName=HannXRQ_Chr09g0265981\|UniProtKB=A0A251TZD4	Helianthus annuus	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a0146781mg\|UniProtKB=A0A022QP11	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_28491\|UniProtKB=A0A1U8EQ87	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400003004\|UniProtKB=M0ZTI1	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc11g071865.1\|UniProtKB=A0A3Q7J139	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107778414\|UniProtKB=A0A1S3YQ23	Nicotiana tabacum	O
TOBAC\|Gene=LOC107798707\|UniProtKB=A0A1S4AKJ3	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi14g01803\|UniProtKB=D7TWS7	Vitis vinifera	O
VITVI\|EnsemblGenome=Vitvi17g00767\|UniProtKB=D7SHV8	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_J02179\|UniProtKB=A0A059AG95	Eucalyptus grandis	O
EUCGR\|EnsemblGenome=EUGRSUZ_K02867\|UniProtKB=A0A059A6K1	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_A06P19610.1\|UniProtKB=A0A078I4N5	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra018087\|UniProtKB=M4DNK0	Brassica campestris	LDO
GOSHI\|Gene=LOC107939811\|UniProtKB=I3NMV7	Gossypium hirsutum	LDO
GOSHI\|Gene=LOC107939274\|UniProtKB=I3NMV2	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_012012\|UniProtKB=A0A061FUE3	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g034748mg\|UniProtKB=A0A067DFC7	Citrus sinensis	LDO
POPTR\|Gene_ORFName=POPTR_015G073300\|UniProtKB=A0A3N7G0I2	Populus trichocarpa	LDO
POPTR\|EnsemblGenome=POPTR_012G078000v3\|UniProtKB=A9PFR4	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_14G068400\|UniProtKB=A0A2C9UJH6	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1511850\|UniProtKB=B9RB61	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_05G035600\|UniProtKB=C6T1P1	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_4g106700\|UniProtKB=G7JNU1	Medicago truncatula	LDO
JUGRE\|Gene=LOC108999200\|UniProtKB=A0A2I4FIT1	Juglans regia	LDO
JUGRE\|Gene=LOC108989081\|UniProtKB=A0A2I4EFD6	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_1G045920\|UniProtKB=A0A0A0LTF8	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_5G177100\|UniProtKB=M5WDB6	Prunus persica	LDO
PHYPA\|EnsemblGenome=Pp3c14_16830\|UniProtKB=A0A2K1JI65	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c3_16770\|UniProtKB=A0A2K1KUR4	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0124s0028\|UniProtKB=A0A2R6W9C8	Marchantia polymorpha	LDO