PANTHER Gene Information

Gene Symbol(s):

SHM6

Organism:

Arabidopsis thaliana

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Gene Name:

Serine hydroxymethyltransferase 6

Gene ID:

2030581

Protein ID:

Q9LM59

Persistent Id:

PTN000188192

Alternate Ids:

SHM6(Symbol)	Serine methylase 6(Synonym)
NP_173621(refSeq)	15219182(GI)
838807(GeneID)	AT1G22020(Ensembl_PRO)
AT1G22020(Ensembl_TRS)	locus:2030581(TAIR)
ANM60843(EMBL-CDS)	AC069252(EMBL)
2.1.2.1(EC)	GLYC6_ARATH(UniProtKB-ID)
AT1G22020(Ensembl)	ARA:AT1G22020-MON(BioCyc)
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PANTHER Classification

PANTHER Family:	SERINE HYDROXYMETHYLTRANSFERASE (PTHR11680)
PANTHER Subfamily:	SERINE HYDROXYMETHYLTRANSFERASE 6 (PTHR11680:SF36)
PANTHER GO-slim Molecular Function:	anion binding organic cyclic compound binding heterocyclic compound binding transferase activity, transferring one-carbon groups
PANTHER GO-slim Biological Process:	L-amino acid biosynthetic process proteinogenic amino acid biosynthetic process folic acid-containing compound metabolic process
PANTHER GO-slim Cellular Component:	mitochondrion
PANTHER protein class:	methyltransferase

Pathway Categories:

Serine glycine biosynthesis

Glycine hydroxymethyltransferase

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	pyridoxal phosphate binding, glycine hydroxymethyltransferase activity
GO BP Complete:	glycine biosynthetic process from serine, tetrahydrofolate interconversion, tetrahydrofolate metabolic process
GO CC Complete:	nucleus, chloroplast, cytoplasm, mitochondrion

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g129467\|UniProtKB=A7SS63	Nematostella vectensis	O
MONBE\|EnsemblGenome=MONBRDRAFT_13528\|UniProtKB=A9UQD9	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_11208\|UniProtKB=A9V8I9	Monosiga brevicollis	O
CRYNJ\|EnsemblGenome=CNJ00410\|UniProtKB=Q5KAU8	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_10586\|UniProtKB=A0A0D1CD49	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_05338\|UniProtKB=E3K747	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_09674\|UniProtKB=E3KI36	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_18481\|UniProtKB=F4NRS4	Batrachochytrium dendrobatidis	O
DICDI\|dictyBase=DDB_G0291652\|UniProtKB=Q54EW1	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_97107\|UniProtKB=F0ZDZ0	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0277947\|UniProtKB=Q54Z26	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_53574\|UniProtKB=F0ZDH7	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_14_1320\|UniProtKB=Q4QFK2	Leishmania major	O
LEIMA\|EnsemblGenome=LMJF_28_2370\|UniProtKB=Q4Q828	Leishmania major	O
TRIV3\|Gene_ORFName=TVAG_109540\|UniProtKB=A2EAE3	Trichomonas vaginalis	O
PLAF7\|EnsemblGenome=PF3D7_1456100\|UniProtKB=Q8IKR8	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_1235600\|UniProtKB=Q8I566	Plasmodium falciparum	O
THAPS\|EnsemblGenome=THAPSDRAFT_26190\|UniProtKB=B8C1A2	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_26031\|UniProtKB=B8CCS6	Thalassiosira pseudonana	O
PHYRM\|Gene=H3GN18_PHYRM\|UniProtKB=H3GN18	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_06g293950v5\|UniProtKB=A0A2K3DQH9	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00070p00192400\|UniProtKB=U5DJ90	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_37G01420\|UniProtKB=A0A0K9P5E9	Zostera marina	O
MUSAM\|EnsemblGenome=Ma10_g10950\|UniProtKB=A0A804KUV9	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma10_g16070\|UniProtKB=A0A804KWS3	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma06_g19130\|UniProtKB=A0A804JHW4	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_000781mg\|UniProtKB=K3XFW2	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3003G373600\|UniProtKB=C5XRB9	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb366470\|UniProtKB=A0A804QY56	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb146170\|UniProtKB=B4F947	Zea mays	O
ORYSJ\|EnsemblGenome=Os05g0429000\|UniProtKB=Q75HP7	Oryza sativa	O
ORYSJ\|EnsemblGenome=Os01g0874900\|UniProtKB=Q8RYY6	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_2g56557v3\|UniProtKB=I1HTW2	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0298480\|UniProtKB=A0A287LXX9	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS3B02G417800\|UniProtKB=A0A3B6FTK1	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3D02G378700\|UniProtKB=A0A3B6GYY7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3A02G385600\|UniProtKB=A0A3B6ER83	Triticum aestivum	O
NELNU\|Gene=LOC104612058\|UniProtKB=A0A1U8BCR6	Nelumbo nucifera	O
VITVI\|EnsemblGenome=Vitvi18g00341\|UniProtKB=F6H0N8	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_F03735\|UniProtKB=A0A059BX41	Eucalyptus grandis	O
BRANA\|Gene_ORFName=DARMORV10_A09P42750.1\|UniProtKB=A0A078H1H9	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra031358\|UniProtKB=M4ERD4	Brassica campestris	LDO
BRANA\|Gene_ORFName=DARMORV10_C08P21280.1\|UniProtKB=A0A078HLR4	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A08P28660.1\|UniProtKB=A0A078HVX0	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra016392\|UniProtKB=M4DIR5	Brassica campestris	LDO
GOSHI\|Gene=LOC107910588\|UniProtKB=A0A1U8K075	Gossypium hirsutum	O
GOSHI\|Gene=LOC107951434\|UniProtKB=A0A1U8NSM9	Gossypium hirsutum	O
GOSHI\|Gene=LOC107924076\|UniProtKB=A0A1U8L5F8	Gossypium hirsutum	O
GOSHI\|Gene=LOC107905031\|UniProtKB=A0A1U8JFK7	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_034999\|UniProtKB=A0A061FGV1	Theobroma cacao	O
POPTR\|EnsemblGenome=POPTR_005G170800v3\|UniProtKB=B9H783	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_002G090200v3\|UniProtKB=B9GUH3	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_18G072100\|UniProtKB=A0A2C9U149	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_1033180\|UniProtKB=B9RJC7	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_04G254300\|UniProtKB=A0A0R0KCM6	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_06G107800\|UniProtKB=K7KUF0	Glycine max	O
MEDTR\|EnsemblGenome=MTR_3g073470\|UniProtKB=G7J467	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr16_03090\|UniProtKB=A0A2I4H0E8	Juglans regia	O
JUGRE\|EnsemblGenome=Jr13_27120\|UniProtKB=A0A2I4DYK5	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_4G377740\|UniProtKB=A0A0A0L3A9	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_1G507600\|UniProtKB=M5XRD3	Prunus persica	O
PRUPE\|EnsemblGenome=PRUPE_1G507500\|UniProtKB=M5Y4X2	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_90314\|UniProtKB=D8RC81	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_235922\|UniProtKB=D8T329	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c4_20570\|UniProtKB=A0A2K1KPA4	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c12_14950\|UniProtKB=A0A2K1JQW3	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c4_11810\|UniProtKB=A0A2K1KN32	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0011s0165\|UniProtKB=A0A2R6XK74	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_001330090\|UniProtKB=A0A0U9HJM4	Klebsormidium nitens	O
NITMS\|EnsemblGenome=Nmar_1793\|UniProtKB=A9A3Y9	Nitrosopumilus maritimus	O
KORCO\|EnsemblGenome=Kcr_0992\|UniProtKB=B1L5K9	Korarchaeum cryptofilum	O
SACS2\|EnsemblGenome=SSO0530\|UniProtKB=Q9UWT5	Sulfolobus solfataricus	O
PYRAE\|EnsemblGenome=PAE0798\|UniProtKB=Q8ZYF9	Pyrobaculum aerophilum	O
METAC\|EnsemblGenome=MA_3520\|UniProtKB=Q8TK94	Methanosarcina acetivorans	O
METJA\|EnsemblGenome=MJ_1597\|UniProtKB=Q58992	Methanocaldococcus jannaschii	O
HALSA\|EnsemblGenome=VNG_1414G\|UniProtKB=Q9HPY5	Halobacterium salinarum	O
THEKO\|EnsemblGenome=TK0528\|UniProtKB=Q5JF06	Thermococcus kodakaraensis	O
CHLAA\|EnsemblGenome=Caur_2543\|UniProtKB=A9WI58	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO5364\|UniProtKB=Q9K4E0	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO4837\|UniProtKB=Q9KZA9	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO5470\|UniProtKB=O86565	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv1093\|UniProtKB=P9WGI9	Mycobacterium tuberculosis	O
MYCTU\|Gene_OrderedLocusName=Rv0070c\|UniProtKB=P9WGI7	Mycobacterium tuberculosis	O
MYCGE\|EnsemblGenome=MG_394\|UniProtKB=P47634	mycoplasma genitalium	O
CLOBH\|Gene_OrderedLocusName=CBO2595\|UniProtKB=A5I526	Clostridium botulinum	O
STRR6\|EnsemblGenome=spr0928\|UniProtKB=Q8DPZ0	Streptococcus pneumoniae	O
STAA8\|EnsemblGenome=SAOUHSC_02354\|UniProtKB=Q2FWE5	Staphylococcus aureus	O
LISMO\|EnsemblGenome=CAD00617\|UniProtKB=Q8Y4B2	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_36900\|UniProtKB=P39148	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_5316\|UniProtKB=Q814V2	Bacillus cereus	O
THEMA\|EnsemblGenome=TM_0720\|UniProtKB=Q9WZH9	Thermotoga maritima	O
DEIRA\|EnsemblGenome=DR_0038\|UniProtKB=Q9RYB2	Deinococcus radiodurans	O
GLOVI\|EnsemblGenome=BAC92310\|UniProtKB=Q7ND67	Gloeobacter violaceus	O
SYNY3\|EnsemblGenome=BAA17124\|UniProtKB=P77962	Synechocystis	O
LEPIN\|EnsemblGenome=LA_1409\|UniProtKB=Q8F6A0	Leptospira interrogans	O
BACTN\|EnsemblGenome=BT_0738\|UniProtKB=Q8A9S7	Bacteroides thetaiotaomicron	O
CHLTR\|EnsemblGenome=CT_432\|UniProtKB=O84439	Chlamydia trachomatis	O
RHOBA\|EnsemblGenome=RB6215\|UniProtKB=Q7UQN2	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_479\|UniProtKB=O66776	Aquifex aeolicus	O
THEYD\|EnsemblGenome=THEYE_A1387\|UniProtKB=B5YFZ0	Thermodesulfovibrio yellowstonii	O
DICTD\|EnsemblGenome=Dtur_0810\|UniProtKB=B8E008	Dictyoglomus turgidum	O
BRADU\|EnsemblGenome=BAC50298\|UniProtKB=P24060	Bradyrhizobium diazoefficiens	O
VIBCH\|EnsemblGenome=VC_A0278\|UniProtKB=Q9KMP4	Vibrio cholerae	O
HELPY\|EnsemblGenome=HP_0183\|UniProtKB=P56089	Helicobacter pylori	O
NEIMB\|EnsemblGenome=NMB1055\|UniProtKB=P56990	Neisseria meningitidis serogroup b	O
GEOSL\|EnsemblGenome=GSU1607\|UniProtKB=Q74CR5	Geobacter sulfurreducens	O
BRADU\|Gene=glyA\|UniProtKB=Q89HS7	Bradyrhizobium diazoefficiens	O
COXBU\|EnsemblGenome=CBU_1419\|UniProtKB=Q83BT3	Coxiella burnetii	O
HAEIN\|EnsemblGenome=HI_0889\|UniProtKB=P43844	Haemophilus influenzae	O
SHEON\|Gene_OrderedLocusName=SO_3471\|UniProtKB=Q8EBN8	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_0941\|UniProtKB=Q9KTG1	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC0690\|UniProtKB=Q8PCN4	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA5415\|UniProtKB=Q9HTE9	Pseudomonas aeruginosa	O
PSEAE\|EnsemblGenome=PA2444\|UniProtKB=Q9I138	Pseudomonas aeruginosa	O
PSEAE\|EnsemblGenome=PA4602\|UniProtKB=Q9HVI7	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM2555\|UniProtKB=P0A2E1	Salmonella typhimurium	O
YERPE\|EnsemblGenome=YP_2548\|UniProtKB=Q8ZCR1	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAA16459\|UniProtKB=P0A825	Escherichia coli	O