PANTHER Gene Information

Gene Symbol(s):

PIM1

Organism:

Bos taurus

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Gene Name:

Serine_threonine-protein kinase pim-1

Gene ID:

ENSBTAG00000000396

Protein ID:

Q9N0P9

Persistent Id:

PTN000541652

Alternate Ids:

PIM1(Synonym)	ENSBTAT00000000511(Ensembl_TRS)
PIM1_BOVIN(UniProtKB-ID)	AF259078(EMBL)
NP_776569(refSeq)	AAF67200(EMBL-CDS)
2.7.11.1(EC)	27806485(GI)
281402(GeneID)	ENSBTAG00000000396(Ensembl)
PIM1(Symbol)	ENSBTAP00000000511(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	SERINE/THREONINE-PROTEIN KINASE PIM (PTHR22984)
PANTHER Subfamily:	SERINE_THREONINE-PROTEIN KINASE PIM-1 (PTHR22984:SF29)
PANTHER GO-slim Molecular Function:	protein serine/threonine kinase activity
PANTHER GO-slim Biological Process:	protein phosphorylation
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	non-receptor serine/threonine protein kinase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ribosomal small subunit binding, ribosomal protein S6 kinase activity, DNA-dependent protein kinase activity, ATP binding, histone H2AT120 kinase activity, AMP-activated protein kinase activity, histone H3S57 kinase activity, histone H4S1 kinase activity, histone H3S28 kinase activity, histone H3T45 kinase activity, manganese ion binding, histone H2AXS139 kinase activity, protein serine kinase activity, histone H3S10 kinase activity, histone H2BS14 kinase activity, histone H2AS1 kinase activity, eukaryotic translation initiation factor 2alpha kinase activity, protein serine/threonine kinase activity, 3-phosphoinositide-dependent protein kinase activity, histone H2AS121 kinase activity, histone H3T3 kinase activity, histone H2BS36 kinase activity, Rho-dependent protein serine/threonine kinase activity, histone H3T11 kinase activity, histone H3T6 kinase activity
GO BP Complete:	positive regulation of cardiac muscle cell proliferation, positive regulation of TORC1 signaling, positive regulation of brown fat cell differentiation, regulation of hematopoietic stem cell proliferation, regulation of transmembrane transporter activity, protein phosphorylation, negative regulation of innate immune response, regulation of mitotic cell cycle, chromatin remodeling, positive regulation of DNA-templated transcription, negative regulation of apoptotic process, apoptotic process, vitamin D receptor signaling pathway, cellular detoxification, cellular response to type II interferon, protein stabilization, positive regulation of cardioblast proliferation
GO CC Complete:	cytoplasm, cytosol, nucleolus, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=8986\|UniProtKB=P11309	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000018118.4\|UniProtKB=H2QSX4	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000015170.3\|UniProtKB=G3S2M1	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000063198.1\|UniProtKB=A0A5F8A759	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000061521.1\|UniProtKB=H9YX84	Macaca mulatta	LDO
MOUSE\|MGI=MGI=97584\|UniProtKB=P06803	Mus musculus	LDO
RAT\|RGD=3330\|UniProtKB=P26794	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00005044206.1\|UniProtKB=A0A8D1NTU1	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000020563.4\|UniProtKB=F6UWX4	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000023702\|UniProtKB=Q95LJ0	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845010485.1\|UniProtKB=A0A8I3N634	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000013454.4\|UniProtKB=F7G9A3	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000050736.1\|UniProtKB=A0A6I8NUU0	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010027085.1\|UniProtKB=A0A8V1ACF6	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000016764.3\|UniProtKB=H9GNL0	Anolis carolinensis	LDO
ORYLA\|Ensembl=ENSORLG00000030307.1\|UniProtKB=A0A3B3HDV3	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-000831-6\|UniProtKB=Q9YHZ5	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000014577.1\|UniProtKB=W5NBD3	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000001653.2\|UniProtKB=H2L884	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-061013-139\|UniProtKB=Q08BC0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000011041.1\|UniProtKB=W5MYU5	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000020864.1\|UniProtKB=H2Y2F9	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000005066.3\|UniProtKB=F6ZM46	Ciona intestinalis	LDO
CAEEL\|WormBase=WBGene00004183\|UniProtKB=Q20443	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG20512\|UniProtKB=A8XXZ2	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00024620\|UniProtKB=A8WQ92	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG09856\|UniProtKB=A8X9T8	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00109393\|UniProtKB=A0A2A6BJH8	Pristionchus pacificus	LDO
HELRO\|EnsemblGenome=HelroG83065\|UniProtKB=T1G4Z9	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g204344\|UniProtKB=A7RZ72	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g222708\|UniProtKB=A7T5T0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g197647\|UniProtKB=A7RIK4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g180174\|UniProtKB=A7RNH5	Nematostella vectensis	O
EMENI\|EnsemblGenome=ANIA_07123\|UniProtKB=C8VDA8	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_1G00230\|UniProtKB=Q4WL45	Neosartorya fumigata	O
GIAIC\|EnsemblGenome=GL50803_17259\|UniProtKB=D3KHH8	Giardia intestinalis	O
PARTE\|EnsemblGenome=GSPATT00024661001\|UniProtKB=A0E9G3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00004179001\|UniProtKB=A0EDE3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00038035001\|UniProtKB=A0CFM8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00034893001\|UniProtKB=A0C3P7	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPS_7188\|UniProtKB=B5YNK8	Thalassiosira pseudonana	O