PANTHER Gene Information

Gene Symbol(s):

OTC

Organism:

Bos taurus

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Tree

Gene Name:

Ornithine transcarbamylase, mitochondrial

Gene ID:

OTC

Protein ID:

Q9N1U7

Persistent Id:

PTN008697445

Alternate Ids:

NM_177487(refSeq)	OTC_BOVIN(UniProtKB-ID)
29135271(GI)	2.1.3.3 {ECO:0000250\|UniProtKB:P00480}(EC)
AF134841(EMBL)	AAF61405(EMBL-CDS)
OTCase {ECO:0000250\|UniProtKB:P00480}(Synonym)	OTC{ECO:0000250\|UniProtKB:P00480}(Symbol)
280887(GeneID)
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PANTHER Classification

PANTHER Family:	ORNITHINE CARBAMOYLTRANSFERASE, MITOCHONDRIAL (PTHR45753)
PANTHER Subfamily:	ORNITHINE TRANSCARBAMYLASE, MITOCHONDRIAL (PTHR45753:SF3)
PANTHER GO-slim Molecular Function:	transferase activity, transferring one-carbon groups
PANTHER GO-slim Biological Process:	L-amino acid biosynthetic process arginine metabolic process proteinogenic amino acid biosynthetic process
PANTHER GO-slim Cellular Component:
PANTHER protein class:	transferase

Pathway Categories:

Arginine biosynthesis

Ornithine carbamoyl transferase

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	amino acid binding, ornithine carbamoyltransferase activity
GO BP Complete:	L-arginine biosynthetic process, ornithine catabolic process, citrulline biosynthetic process, urea cycle, arginine biosynthetic process via ornithine, ammonium homeostasis
GO CC Complete:	mitochondrial matrix, mitochondrion, mitochondrial inner membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=8512\|UniProtKB=P00480	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000051070.1\|UniProtKB=A0A2I3TF75	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000021799.3\|UniProtKB=H2QYG7	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000011703.3\|UniProtKB=G3R7S1	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000013493.4\|UniProtKB=F6ZKS9	Macaca mulatta	O
MOUSE\|MGI=MGI=97448\|UniProtKB=P11725	Mus musculus	O
RAT\|RGD=3236\|UniProtKB=P00481	Rattus norvegicus	O
PIG\|Gene=OTC\|UniProtKB=O19072	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000012236.6\|UniProtKB=A0A480E1W6	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000022838.4\|UniProtKB=F6UW24	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000010876.6\|UniProtKB=M3WE39	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845025700.1\|UniProtKB=A0A8I3S5H5	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000021104.3\|UniProtKB=F6UHY3	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000007118.3\|UniProtKB=A0A6I8PCR4	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010002770.1\|UniProtKB=A0A8V0XEC2	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00015003941\|UniProtKB=Q9YHY9	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000014619.3\|UniProtKB=G1KQ60	Anolis carolinensis	O
XENLA\|Gene=otc.S\|UniProtKB=A0A8J1MB06	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-982300\|UniProtKB=Q6DJ41	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000009056.2\|UniProtKB=H2LYY6	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-070912-422\|UniProtKB=E9QHD9	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000007928.1\|UniProtKB=W5MML8	lepisosteus oculatus	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_287613\|UniProtKB=C3Z6N9	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC588878\|UniProtKB=A0A7M7HFR5	Strongylocentrotus purpuratus	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g182282\|UniProtKB=A7RV06	Nematostella vectensis	O
YEAST\|SGD=S000003624\|UniProtKB=P05150	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AFR098W\|UniProtKB=Q754H4	Eremothecium gossypii	O
CANAL\|CGD=CAL0000176534\|UniProtKB=Q5ABU0	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_D14894g\|UniProtKB=Q6C924	Yarrowia lipolytica	O
EMENI\|Gene_ORFName=AN4409\|UniProtKB=P11803	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_4G07190\|UniProtKB=Q4WNW5	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU01667\|UniProtKB=Q1K5I2	Neurospora crassa	O
SCLS1\|Gene_ORFName=SS1G_10630\|UniProtKB=A7EZ64	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_05206\|UniProtKB=Q0USQ8	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC4G9.10\|UniProtKB=P31317	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_00635\|UniProtKB=B6JW65	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNC04300\|UniProtKB=Q5KK45	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_03537\|UniProtKB=A0A0D1DW09	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_12127\|UniProtKB=E3KPE6	Puccinia graminis	O
GIAIC\|EnsemblGenome=GL50803_10311\|UniProtKB=E2RTT6	Giardia intestinalis	O
TRIV3\|Gene_ORFName=TVAG_041310\|UniProtKB=A2G3U5	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_038530\|UniProtKB=A2DY09	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_368740\|UniProtKB=A2EUY0	Trichomonas vaginalis	O
THAPS\|EnsemblGenome=THAPSDRAFT_997\|UniProtKB=B8BT16	Thalassiosira pseudonana	O
PHYRM\|Gene=H3HCG4_PHYRM\|UniProtKB=H3HCG4	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_12g489700v5\|UniProtKB=A8ILJ9	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00011p00222000\|UniProtKB=W1NGS5	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_56G00760\|UniProtKB=A0A0K9NY32	Zostera marina	O
MUSAM\|EnsemblGenome=Ma06_g10580\|UniProtKB=A0A804JEU1	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_017196mg\|UniProtKB=K3YSF2	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3004G268100\|UniProtKB=C5Y0C0	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb188330\|UniProtKB=C4IZ94	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb001310\|UniProtKB=A0A804PNG1	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb255250\|UniProtKB=A0A804PPP6	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb126200\|UniProtKB=A0A804N0U8	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb216710\|UniProtKB=A0A804P8V2	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb403320\|UniProtKB=A0A804UKL8	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb252020\|UniProtKB=A0A1D6HHJ4	Zea mays	O
ORYSJ\|EnsemblGenome=Os02g0704800\|UniProtKB=Q6YVI0	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_3g52727v3\|UniProtKB=I1ID02	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0607460\|UniProtKB=F2EEY9	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS6B02G299700\|UniProtKB=A0A3B6PQN7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6D02G252300\|UniProtKB=A0A3B6QH04	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6A02G272200\|UniProtKB=A0A3B6NR27	Triticum aestivum	O
NELNU\|Gene=LOC104595651\|UniProtKB=A0A1U7ZZT9	Nelumbo nucifera	O
SPIOL\|Gene=LOC110789105\|UniProtKB=A0A9R0IHZ9	Spinacia oleracea	O
HELAN\|Gene_ORFName=HanXRQr2_Chr07g0285601\|UniProtKB=A0A9K3NF37	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C600304330\|UniProtKB=A0A9R1X6B4	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a008393mg\|UniProtKB=A0A022R3E7	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_13290\|UniProtKB=A0A1U8GBM0	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400003741\|UniProtKB=M0ZWK1	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc04g080610.3\|UniProtKB=K4BVE0	Solanum lycopersicum	O
TOBAC\|Gene=LOC107819553\|UniProtKB=A0A1S4CJ12	Nicotiana tabacum	O
TOBAC\|Gene=LOC107822172\|UniProtKB=A0A1S4CST9	Nicotiana tabacum	O
CAPAN\|EnsemblGenome=T459_16731\|UniProtKB=A0A2G2Z9N5	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_30989\|UniProtKB=A0A2G2YA09	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400015463\|UniProtKB=M1B932	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc12g089210.2\|UniProtKB=A0A3Q7JD34	Solanum lycopersicum	O
TOBAC\|Gene=LOC107799727\|UniProtKB=A0A1S4APF3	Nicotiana tabacum	O
TOBAC\|Gene=LOC107786954\|UniProtKB=A0A1S3ZHV9	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi18g00986\|UniProtKB=E0CQF4	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_F01880\|UniProtKB=A0A059BQQ2	Eucalyptus grandis	O
BRANA\|Gene_ORFName=GSBRNA2T00063737001\|UniProtKB=A0A078HH90	Brassica napus	O
BRACM\|EnsemblGenome=Bra003758\|UniProtKB=A0A397YSN9	Brassica campestris	O
ARATH\|TAIR=locus=2018467\|UniProtKB=O50039	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107905438\|UniProtKB=A0A1U8JBA0	Gossypium hirsutum	O
GOSHI\|Gene=LOC107943527\|UniProtKB=A0A1U8N4J3	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_034077\|UniProtKB=A0A061FJZ0	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g024871mg\|UniProtKB=A0A067HA10	Citrus sinensis	O
POPTR\|Gene_ORFName=POPTR_005G229400\|UniProtKB=A0A3N7F6U3	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_05G157200\|UniProtKB=A0A2C9VY17	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_1595060\|UniProtKB=B9R7X3	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_04G030500\|UniProtKB=K7KHU1	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_06G030600\|UniProtKB=A0A368UI50	Glycine max	O
MEDTR\|EnsemblGenome=MTR_1g022420\|UniProtKB=A0A072VEY9	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_3g112050\|UniProtKB=A0A072V483	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr11_21080\|UniProtKB=A0A2I4ENX0	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_3G859690\|UniProtKB=A0A0A0LGM8	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_1G376500\|UniProtKB=M5XE79	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_158392\|UniProtKB=D8SUH0	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_184194\|UniProtKB=D8SZY7	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c9_2740\|UniProtKB=A0A7I4EKS7	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c9_2745\|UniProtKB=A0A2K1K1Q1	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c15_7070\|UniProtKB=A0A7I4B1K1	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0003s0042\|UniProtKB=A0A2R6XSQ1	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_001100160\|UniProtKB=A0A1Y1HXA5	Klebsormidium nitens	O
NITMS\|EnsemblGenome=Nmar_0397\|UniProtKB=A9A594	Nitrosopumilus maritimus	O
KORCO\|EnsemblGenome=Kcr_1331\|UniProtKB=B1L6J8	Korarchaeum cryptofilum	O
KORCO\|EnsemblGenome=Kcr_1251\|UniProtKB=B1L6B8	Korarchaeum cryptofilum	O
KORCO\|EnsemblGenome=Kcr_0501\|UniProtKB=B1L475	Korarchaeum cryptofilum	O
SACS2\|EnsemblGenome=SSO0871\|UniProtKB=Q97ZM1	Sulfolobus solfataricus	O
PYRAE\|EnsemblGenome=PAE1985\|UniProtKB=Q8ZW40	Pyrobaculum aerophilum	O
METAC\|EnsemblGenome=MA_3310\|UniProtKB=Q8TKT5	Methanosarcina acetivorans	O
METJA\|EnsemblGenome=MJ_0881\|UniProtKB=Q58291	Methanocaldococcus jannaschii	O
HALSA\|EnsemblGenome=VNG_6315G\|UniProtKB=Q48296	Halobacterium salinarum	O
THEKO\|EnsemblGenome=TK0871\|UniProtKB=Q5JI16	Thermococcus kodakaraensis	O
STRCO\|Gene_OrderedLocusName=SCO5976\|UniProtKB=Q93JF1	Streptomyces coelicolor	O
CLOBH\|Gene_OrderedLocusName=CBO2593\|UniProtKB=A5I524	Clostridium botulinum	O
STRR6\|EnsemblGenome=spr1957\|UniProtKB=P65608	Streptococcus pneumoniae	O
STAA8\|EnsemblGenome=SAOUHSC_02968\|UniProtKB=Q2FUX8	Staphylococcus aureus	O
BACCR\|EnsemblGenome=BC_0407\|UniProtKB=Q81II0	Bacillus cereus	O
STAA8\|EnsemblGenome=SAOUHSC_01128\|UniProtKB=Q2FZB0	Staphylococcus aureus	O
THEMA\|EnsemblGenome=TM_1097\|UniProtKB=P96108	Thermotoga maritima	O
NEIMB\|EnsemblGenome=NMB1573\|UniProtKB=P0DH57	Neisseria meningitidis serogroup b	O
HAEIN\|EnsemblGenome=HI_0596\|UniProtKB=P44770	Haemophilus influenzae	O
VIBCH\|EnsemblGenome=VC_2508\|UniProtKB=Q9KP68	Vibrio cholerae	O
PSEAE\|EnsemblGenome=PA5172\|UniProtKB=P08308	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM4469\|UniProtKB=Q08016	Salmonella typhimurium	O
YERPE\|EnsemblGenome=YP_0638\|UniProtKB=Q8ZBG8	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAE76057\|UniProtKB=P06960	Escherichia coli	O
ECOLI\|EnsemblGenome=BAE78251\|UniProtKB=P04391	Escherichia coli	O
SALTY\|EnsemblGenome=STM4465\|UniProtKB=Q8ZK35	Salmonella typhimurium	O
MYCTU\|Gene_OrderedLocusName=Rv1656\|UniProtKB=P9WIT9	Mycobacterium tuberculosis	O
CLOBH\|Gene_OrderedLocusName=CBO2885\|UniProtKB=A5I5W9	Clostridium botulinum	O
LISMO\|EnsemblGenome=CAC98251\|UniProtKB=Q8YAS7	Listeria monocytogenes	O
LISMO\|EnsemblGenome=CAC99665\|UniProtKB=Q8Y6U5	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_11250\|UniProtKB=P18186	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_4126\|UniProtKB=Q818W3	Bacillus cereus	O
DEIRA\|EnsemblGenome=DR_0080\|UniProtKB=Q9RY70	Deinococcus radiodurans	O
GLOVI\|EnsemblGenome=BAC91042\|UniProtKB=Q7NGR7	Gloeobacter violaceus	O
SYNY3\|EnsemblGenome=BAA10847\|UniProtKB=Q55497	Synechocystis	O
LEPIN\|EnsemblGenome=LA_2840\|UniProtKB=Q8F2D1	Leptospira interrogans	O
BACTN\|EnsemblGenome=BT_3717\|UniProtKB=Q8A1E9	Bacteroides thetaiotaomicron	O
RHOBA\|EnsemblGenome=RB5986\|UniProtKB=Q7UQZ6	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_1711\|UniProtKB=O67607	Aquifex aeolicus	O
THEYD\|EnsemblGenome=THEYE_A0670\|UniProtKB=B5YJU7	Thermodesulfovibrio yellowstonii	O
GEOSL\|EnsemblGenome=GSU0152\|UniProtKB=Q74GU2	Geobacter sulfurreducens	O
BRADU\|EnsemblGenome=BAC46364\|UniProtKB=Q89VE8	Bradyrhizobium diazoefficiens	O
SHEON\|Gene_OrderedLocusName=SO_0277\|UniProtKB=Q8EK29	Shewanella oneidensis	O
XANCP\|EnsemblGenome=XCC2249\|UniProtKB=Q8P8J2	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA3537\|UniProtKB=P11724	Pseudomonas aeruginosa	O
ECOLI\|EnsemblGenome=BAE76936\|UniProtKB=Q46803	Escherichia coli	O