PANTHER Gene Information

Gene Symbol(s):

Y45G12B.3

Organism:

Caenorhabditis elegans

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Gene Name:

L-2-hydroxyglutarate dehydrogenase, mitochondrial

Gene ID:

WBGene00021564

Protein ID:

Q9N4Z0

Persistent Id:

PTN000354442

Alternate Ids:

178733(GeneID)	FO080651(EMBL)
L2HDH(Synonym)	WBGene00021564(WormBase)
Y45G12B.3a(WormBase_TRS)	WBGene00021564(Ensembl)
CCD65497(EMBL-CDS)	Y45G12B.3a(Ensembl_PRO)
NP_503730(refSeq)	75023322(GI)
Y45G12B.3a(Ensembl_TRS)	1.1.99.2(EC)
L2HDH_CAEEL(UniProtKB-ID)	CE28366(WormBase_PRO)
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PANTHER Classification

PANTHER Family:	L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL (PTHR43104)
PANTHER Subfamily:	L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL (PTHR43104:SF2)
PANTHER GO-slim Molecular Function:	oxidoreductase activity, acting on CH-OH group of donors
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	dehydrogenase

Pathway Categories:

Ornithine degradation

Aminobutyraldehyde dehydrogenase

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	oxidoreductase activity, acting on CH-OH group of donors, oxidoreductase activity, 2-hydroxyglutarate dehydrogenase activity
GO BP Complete:	-
GO CC Complete:	mitochondrion

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

The citric acid (TCA) cycle and respiratory electron transport, Pyruvate metabolism and Citric Acid (TCA) cycle, Interconversion of 2-oxoglutarate and 2-hydroxyglutarate, Metabolism

Orthologs

ID	Organism	Type
HUMAN\|HGNC=20499\|UniProtKB=Q9H9P8	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000006329.5\|UniProtKB=A0A2I3SKZ1	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000003027.3\|UniProtKB=A0A2I2YPQ7	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000007468.4\|UniProtKB=F6SVX9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2384968\|UniProtKB=Q91YP0	Mus musculus	LDO
RAT\|RGD=1306250\|UniProtKB=D3ZVS2	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000015200\|UniProtKB=A7MBI3	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000005016.5\|UniProtKB=A0A286ZQZ4	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000020354.4\|UniProtKB=A0A9L0R891	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000025658.4\|UniProtKB=A0A337SQN0	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845002841.1\|UniProtKB=A0A8I3RSG8	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000007728.3\|UniProtKB=A0A5F8HDK7	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000013978.3\|UniProtKB=F6USC1	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010019259.1\|UniProtKB=A0A8V0ZGL8	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000001723.3\|UniProtKB=H9G5H9	Anolis carolinensis	LDO
XENLA\|Gene=l2hgdh.L\|UniProtKB=A0A1L8F9P7	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5764342\|UniProtKB=F6QMX5	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000009117.2\|UniProtKB=H2LZ62	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-090319-6\|UniProtKB=B8A6D3	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000011835.1\|UniProtKB=W5N1P6	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000006381.3\|UniProtKB=F6RKR7	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118425660\|UniProtKB=A0A9J7LZH6	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC578357\|UniProtKB=A0A7M7PR24	Strongylocentrotus purpuratus	LDO
CAEBR\|WormBase=WBGene00028888\|UniProtKB=A8X2R1	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00118584\|UniProtKB=A0A2A6CGH6	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0032729\|UniProtKB=Q9VJ28	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP007868\|UniProtKB=Q7Q3G9	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC007941\|UniProtKB=D2A385	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC007940\|UniProtKB=D2A384	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_305386\|UniProtKB=E9GS31	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG179569\|UniProtKB=T1FEW0	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g172254\|UniProtKB=A7SMW7	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG51164\|UniProtKB=B3SCQ1	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_14006\|UniProtKB=A9UPQ3	Monosiga brevicollis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_28787\|UniProtKB=F4PF51	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0267656\|UniProtKB=Q55GI5	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_33881\|UniProtKB=F0ZLQ4	Dictyostelium purpureum	LDO
PARTE\|EnsemblGenome=GSPATT00031234001\|UniProtKB=A0BR38	Paramecium tetraurelia	LDO
SELML\|EnsemblGenome=SELMODRAFT_88360\|UniProtKB=D8RA38	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_166561\|UniProtKB=D8QZ22	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c25_9310\|UniProtKB=A0A2K1IEC6	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0085s0100\|UniProtKB=A0A2R6WJ58	Marchantia polymorpha	LDO
NITMS\|EnsemblGenome=Nmar_0409\|UniProtKB=A9A5A6	Nitrosopumilus maritimus	LDO
STRCO\|Gene_OrderedLocusName=SCO4113\|UniProtKB=Q9F303	Streptomyces coelicolor	LDO
GLOVI\|Gene=Q7NIH6_GLOVI\|UniProtKB=Q7NIH6	Gloeobacter violaceus	LDO
SYNY3\|Gene=P74590_SYNY3\|UniProtKB=P74590	Synechocystis	LDO
LEPIN\|EnsemblGenome=LA_1578\|UniProtKB=Q8F5T9	Leptospira interrogans	LDO
RHOBA\|EnsemblGenome=RB10062\|UniProtKB=Q7UKM2	Rhodopirellula baltica	LDO
THEYD\|EnsemblGenome=THEYE_A1961\|UniProtKB=B5YIC0	Thermodesulfovibrio yellowstonii	LDO
HELPY\|EnsemblGenome=HP_0086\|UniProtKB=O24913	Helicobacter pylori	LDO
BRADU\|Gene=Q89E94_BRADU\|UniProtKB=Q89E94	Bradyrhizobium diazoefficiens	LDO
COXBU\|EnsemblGenome=CBU_1839\|UniProtKB=Q83AP2	Coxiella burnetii	LDO
VIBCH\|EnsemblGenome=VC_A0147\|UniProtKB=Q9KN19	Vibrio cholerae	LDO
PSEAE\|EnsemblGenome=PA5418\|UniProtKB=Q9HTE6	Pseudomonas aeruginosa	LDO
SALTY\|EnsemblGenome=STM2790\|UniProtKB=Q8ZMM3	Salmonella typhimurium	LDO
ECOLI\|EnsemblGenome=BAA16521\|UniProtKB=P37339	Escherichia coli	LDO