PANTHER Gene Information   
Gene Symbol(s): Ccn2
Organism: Rattus norvegicus
View Gene in Tree
Tree Reduced Tree  
Tree Reduced Tree
Gene Name: CCN family member 2
Gene ID: 621392
Protein ID: Q9R1E9
Persistent Id: PTN000142898
Alternate Ids:
CCN2_RAT(UniProtKB-ID) NP_071602(refSeq)
46981902(GI) Q9WVS1(AltAccession)
AF120275(EMBL) BAA82125(EMBL-CDS)
Connective tissue growth-related protein(Synonym) Ccn2{ECO:0000312|RGD:621392}(Symbol)
64032(GeneID) 621392(RGD)
Show All

PANTHER Classification
PANTHER Family: CONNECTIVE TISSUE GROWTH FACTOR-RELATED (PTHR11348)
PANTHER Subfamily: CCN FAMILY MEMBER 2 (PTHR11348:SF7)  
PANTHER GO-slim Molecular Function: heparin binding
integrin binding
PANTHER GO-slim Biological Process: positive regulation of cell differentiation
cell adhesion
signal transduction
PANTHER GO-slim Cellular Component: extracellular space
extracellular matrix
PANTHER protein class: growth factor
Pathway Categories: No pathway information available
GO MF Complete: growth factor activity, fibronectin binding, integrin binding, heparin binding
GO BP Complete: regulation of chondrocyte differentiation, positive regulation of cell population proliferation, chondrocyte differentiation, response to amino acid, fibroblast growth factor receptor signaling pathway, cell adhesion, microtubule depolymerization, integrin-mediated signaling pathway, positive regulation of collagen biosynthetic process, cartilage condensation, response to mineralocorticoid, cellular response to fatty acid, ossification, angiogenesis, cellular response to glucose stimulus, DNA biosynthetic process, response to fatty acid, cell migration, intracellular signal transduction, lung development, cell-matrix adhesion, positive regulation of cardiac muscle contraction, signal transduction, positive regulation of cell differentiation, response to organic cyclic compound, response to peptide hormone, connective tissue development, tissue homeostasis, negative regulation of gene expression, reactive oxygen species metabolic process, calcium ion transmembrane import into cytosol, positive regulation of stress fiber assembly, positive regulation of gene expression, positive regulation of JNK cascade, positive regulation of protein phosphorylation, positive regulation of ERK1 and ERK2 cascade, response to estradiol, chondrocyte proliferation, response to anoxia, positive regulation of cell activation, extracellular matrix constituent secretion, positive regulation of G0 to G1 transition, cellular response to interleukin-13, positive regulation of apoptotic signaling pathway
GO CC Complete: extracellular space, perinuclear region of cytoplasm, cell cortex, intracellular membrane-bounded organelle, Golgi apparatus, extracellular matrix, extracellular region
Reactome Pathways: -