PANTHER Gene Information

Gene Symbol(s):

CELE_Y48B6A.13

Organism:

Caenorhabditis elegans

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Gene Name:

Diphosphomevalonate decarboxylase

Gene ID:

WBGene00012984

Protein ID:

Q9U294

Persistent Id:

PTN000104632

Alternate Ids:

NP_496966(refSeq)	Q9U294_CAEEL(UniProtKB-ID)
WBGene00012984(WormBase)	175078(GeneID)
Y48B6A(WormBase_TRS)	CE22129(WormBase_PRO)
BX284602(EMBL)	Q9U294(Synonym)
WBGene00012984(Ensembl)	CAB54454(EMBL-CDS)
5824811(GI)
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PANTHER Classification

PANTHER Family:	DIPHOSPHOMEVALONATE DECARBOXYLASE (PTHR10977)
PANTHER Subfamily:	DIPHOSPHOMEVALONATE DECARBOXYLASE (PTHR10977:SF3)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	decarboxylase

Pathway Categories:

Cholesterol biosynthesis

Diphosphomevalonate decarboxylase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	nucleotide binding, ATP binding, lyase activity, diphosphomevalonate decarboxylase activity, carboxy-lyase activity
GO BP Complete:	isopentenyl diphosphate biosynthetic process, mevalonate pathway, lipid metabolic process, cholesterol biosynthetic process, cholesterol metabolic process, steroid metabolic process, steroid biosynthetic process, isoprenoid biosynthetic process, sterol biosynthetic process
GO CC Complete:	cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Synthesis of Dolichyl-phosphate, Asparagine N-linked glycosylation, Metabolism of steroids, Synthesis of substrates in N-glycan biosythesis, Metabolism of lipids, Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein, Post-translational protein modification, Cholesterol biosynthesis, Metabolism of proteins, Metabolism

Orthologs

ID	Organism	Type
HUMAN\|HGNC=7529\|UniProtKB=P53602	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000008459.5\|UniProtKB=H2QBQ1	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000012548.3\|UniProtKB=G3R9Z3	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000014326.4\|UniProtKB=F6Q304	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2179327\|UniProtKB=Q99JF5	Mus musculus	LDO
RAT\|RGD=621292\|UniProtKB=Q62967	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000012059\|UniProtKB=Q0P570	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000034905.3\|UniProtKB=A0A287AB49	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000011206.4\|UniProtKB=F6ZMR1	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000006656.6\|UniProtKB=M3W6A2	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845003495.1\|UniProtKB=A0A8I3RRE8	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000004189.2\|UniProtKB=F6Y9W8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000011366.4\|UniProtKB=F6U2Q4	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010009646.1\|UniProtKB=A0A8V0Y2W7	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000006654.3\|UniProtKB=H9GBS4	Anolis carolinensis	LDO
XENLA\|Gene=mvd.L\|UniProtKB=A0A1L8GL39	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-975218\|UniProtKB=A0A6I8RS93	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000009351.2\|UniProtKB=H2M002	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-041114-127\|UniProtKB=Q5U403	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000001275.1\|UniProtKB=W5LZA1	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000005220.3\|UniProtKB=F6Z0U1	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_277163\|UniProtKB=C3ZGP5	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC764382\|UniProtKB=A0A7M7N4W9	Strongylocentrotus purpuratus	LDO
CAEBR\|WormBase=WBGene00039599\|UniProtKB=A8XYB1	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00112296\|UniProtKB=A0A2A6B894	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0030683\|UniProtKB=Q9VXQ3	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP001611\|UniProtKB=Q7PXV2	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC003224\|UniProtKB=D6WE42	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_301631\|UniProtKB=E9G9U6	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW022273\|UniProtKB=B7QEF4	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG185177\|UniProtKB=T1FMH1	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g118942\|UniProtKB=A7SHV3	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG55561\|UniProtKB=B3RV83	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_26828\|UniProtKB=A9V3M8	Monosiga brevicollis	LDO
YEAST\|SGD=S000005326\|UniProtKB=P32377	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AGL232C\|UniProtKB=Q751D8	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000181620\|UniProtKB=A0A1D8PC43	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_F05632g\|UniProtKB=Q6C2S1	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_04414\|UniProtKB=Q5B4W6	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_4G07130\|UniProtKB=Q4WNV9	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU11381\|UniProtKB=A7UX64	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_03958\|UniProtKB=A7EF67	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_04832\|UniProtKB=Q0UTT2	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC24C9.03\|UniProtKB=O13963	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_03349\|UniProtKB=B6K402	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNL04950\|UniProtKB=Q5K8P5	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_05179\|UniProtKB=A0A0D1C9W4	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_06637\|UniProtKB=E3K945	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_34046\|UniProtKB=F4NUN3	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0278607\|UniProtKB=Q54YQ9	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_32847\|UniProtKB=F0ZJV5	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_18_0020\|UniProtKB=Q4QE40	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb10.61.2745\|UniProtKB=Q388J2	Trypanosoma brucei	LDO
TRYB2\|Gene_ORFName=Tb10.05.0010\|UniProtKB=Q388P2	Trypanosoma brucei	LDO
GIAIC\|EnsemblGenome=GL50803_23420\|UniProtKB=A8BKG7	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_302660\|UniProtKB=A2EGU1	Trichomonas vaginalis	LDO
PARTE\|EnsemblGenome=GSPATT00008724001\|UniProtKB=A0CNB5	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_15226\|UniProtKB=B8BS75	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3HB33_PHYRM\|UniProtKB=H3HB33	Phytophthora ramorum	LDO
AMBTC\|EnsemblGenome=AMTR_s00114p00051110\|UniProtKB=W1NPU6	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_156G00320\|UniProtKB=A0A0K9PXM2	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma06_g17700\|UniProtKB=A0A804JHE3	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_022131mg\|UniProtKB=K3Z6G2	Setaria italica	O
SETIT\|EnsemblGenome=SETIT_017062mg\|UniProtKB=K3YS18	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3004G330600\|UniProtKB=C5XUG8	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb257840\|UniProtKB=B6TCA9	Zea mays	LDO
MAIZE\|EnsemblGenome=Zm00001eb056620\|UniProtKB=A0A804M3L1	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os02g0109100\|UniProtKB=Q6ETS8	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_2g61850v3\|UniProtKB=I1HVJ7	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0326430\|UniProtKB=A0A8I6XVE4	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS3B02G585400\|UniProtKB=W5D5D7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7A02G156400\|UniProtKB=A0A3B6RET4	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3A02G517800\|UniProtKB=A0A3B6ESQ2	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3D02G525300\|UniProtKB=A0A3B6H780	Triticum aestivum	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0519810\|UniProtKB=A0A8I7BFL1	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS5B02G447300\|UniProtKB=A0A3B6LV38	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5A02G442800\|UniProtKB=A0A3B6KPG3	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5D02G450200\|UniProtKB=A0A3B6N012	Triticum aestivum	LDO
NELNU\|Gene=LOC104588425\|UniProtKB=A0A1U7YW07	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110795215\|UniProtKB=A0A9R0IWU6	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr14g0660761\|UniProtKB=A0A251TBE0	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C200088690\|UniProtKB=A0A9R1WHB2	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C900474640\|UniProtKB=A0A9R1UG29	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a007068mg\|UniProtKB=A0A022PZU6	Erythranthe guttata	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400016014\|UniProtKB=M1BB88	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc04g009655.1\|UniProtKB=A0A3Q7G080	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107759723\|UniProtKB=A0A1S3WZY8	Nicotiana tabacum	O
TOBAC\|Gene=LOC107763449\|UniProtKB=A0A1S3XBX7	Nicotiana tabacum	LDO
CAPAN\|EnsemblGenome=T459_29703\|UniProtKB=A0A2G2Y6C6	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400023978\|UniProtKB=M1C7S0	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc11g007020.2\|UniProtKB=A8WBX7	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107817230\|UniProtKB=A0A1S4CBJ6	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107811776\|UniProtKB=A0A1S4BTP3	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi13g00887\|UniProtKB=D7TXN8	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_G02693\|UniProtKB=A0A059BH19	Eucalyptus grandis	O
EUCGR\|EnsemblGenome=EUGRSUZ_J00991\|UniProtKB=A0A059ABM6	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_C04P38200.1\|UniProtKB=A0A078JFC7	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra007059\|UniProtKB=M4CS67	Brassica campestris	O
BRACM\|EnsemblGenome=Bra014828\|UniProtKB=M4DEA7	Brassica campestris	LDO
ARATH\|TAIR=locus=2064092\|UniProtKB=O23722	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2080265\|UniProtKB=F4JCU3	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107920209\|UniProtKB=A0A1U8KW38	Gossypium hirsutum	O
GOSHI\|Gene=LOC107933302\|UniProtKB=A0A1U8M2E2	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_043879\|UniProtKB=A0A061FWD6	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g014714mg\|UniProtKB=A0A067DVM6	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_008G021100v3\|UniProtKB=B9HKQ7	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_010G237900v3\|UniProtKB=B9HVY0	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_10G058800\|UniProtKB=A0A2C9V4W6	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_07G087500\|UniProtKB=A0A2C9VL99	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0888230\|UniProtKB=B9S5A3	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_10G279800\|UniProtKB=I1LF24	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_20G109900\|UniProtKB=I1NFB9	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g112230\|UniProtKB=A0A072W240	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr05_04410\|UniProtKB=A0A2I4FUL3	Juglans regia	O
JUGRE\|Gene=LOC109009861\|UniProtKB=A0A2I4GQ73	Juglans regia	O
JUGRE\|EnsemblGenome=Jr14_04840\|UniProtKB=A0A2I4E1Q3	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_5G615210\|UniProtKB=A0A0A0KRF9	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_2G078900\|UniProtKB=M5WUF1	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_135101\|UniProtKB=D8T9Q4	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_268244\|UniProtKB=D8S7G7	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c6_12700\|UniProtKB=A0A7I4DWY8	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c5_15100\|UniProtKB=A0A7I4DR74	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0007s0128\|UniProtKB=A0A2R6XNN9	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_007740040\|UniProtKB=A0A1Y1IQ62	Klebsormidium nitens	LDO
SACS2\|EnsemblGenome=SSO2989\|UniProtKB=Q97UL5	Sulfolobus solfataricus	LDO