PANTHER Gene Information

Gene Symbol(s):

ndx-4

Organism:

Caenorhabditis elegans

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Gene Name:

Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]

Gene ID:

WBGene00003581

Protein ID:

Q9U2M7

Persistent Id:

PTN000482050

Alternate Ids:

WBGene00003581(WormBase)	CE20230(WormBase_PRO)
CAB63351(EMBL-CDS)	189639(GeneID)
3.6.1.-(EC)	NM_061012(refSeq)
WBGene00003581(Ensembl)	21465914(GI)
ndx-4(Symbol)	AP4A_CAEEL(UniProtKB-ID)
Nudix hydrolase 4(Synonym)	Y37H9A.6(Ensembl_TRS)
Y37H9A.6(Ensembl_PRO)	AL032625(EMBL)
Y37H9A(WormBase_TRS)
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PANTHER Classification

PANTHER Family:	DIADENOSINE 5,5-P1,P4-TETRAPHOSPHATE PYROPHOSPHOHYDROLASE MUTT (PTHR21340)
PANTHER Subfamily:	BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE [ASYMMETRICAL] (PTHR21340:SF0)
PANTHER GO-slim Molecular Function:	pyrophosphatase activity
PANTHER GO-slim Biological Process:	purine ribonucleoside monophosphate metabolic process ATP biosynthetic process
PANTHER GO-slim Cellular Component:
PANTHER protein class:	hydrolase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ATP binding, bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity, bis(5'-nucleosyl)-tetraphosphatase activity, 5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity, hydrolase activity
GO BP Complete:	ADP biosynthetic process, apoptotic process, ribose phosphate metabolic process, AMP biosynthetic process, diadenosine tetraphosphate catabolic process, ATP biosynthetic process
GO CC Complete:	cellular_component

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Cellular responses to stress, Cellular response to chemical stress, Detoxification of Reactive Oxygen Species, Cellular responses to stimuli

Orthologs

ID	Organism	Type
HUMAN\|HGNC=8049\|UniProtKB=P50583	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000020876.6\|UniProtKB=H2QX59	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000003907.3\|UniProtKB=G3QMT3	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000051675.1\|UniProtKB=F7HCE0	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1913651\|UniProtKB=P56380	Mus musculus	LDO
RAT\|RGD=1303023\|UniProtKB=Q6PEC0	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000031793\|UniProtKB=Q29RJ1	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000010981\|UniProtKB=P50584	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000011552.3\|UniProtKB=A0A9L0TLJ2	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000023876.4\|UniProtKB=M3X650	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845023059.1\|UniProtKB=A0A8I3PR56	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000049625.1\|UniProtKB=A0A5F8GG60	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000040448.1\|UniProtKB=A0A6I8P011	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010011911.1\|UniProtKB=R4GJX0	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000013079.3\|UniProtKB=A0A803T3U0	Anolis carolinensis	LDO
XENLA\|Gene=nudt2.S\|UniProtKB=A0A1L8HRP9	Xenopus laevis	O
XENLA\|Gene=nudt2.L\|UniProtKB=A5D8R0	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1008721\|UniProtKB=Q28GY0	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000008680.2\|UniProtKB=H2LXM7	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040718-7\|UniProtKB=Q6DG97	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000004965.1\|UniProtKB=W5MC59	lepisosteus oculatus	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_277165\|UniProtKB=C3ZGP8	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC756144\|UniProtKB=A0A7M7NBP8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC756973\|UniProtKB=A0A7M7G141	Strongylocentrotus purpuratus	LDO
CAEBR\|WormBase=WBGene00034373\|UniProtKB=A8XIC9	Caenorhabditis briggsae	LDO
DROME\|FlyBase=FBgn0287788\|UniProtKB=Q4V6M1	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP008495\|UniProtKB=Q7Q4N2	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC031183\|UniProtKB=A0A139WFV7	Tribolium castaneum	LDO
HELRO\|EnsemblGenome=HelroG164652\|UniProtKB=T1EVP2	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g248108\|UniProtKB=A7SYM4	Nematostella vectensis	LDO
ASPFU\|EnsemblGenome=AFUA_3G02870\|UniProtKB=Q4WFA6	Neosartorya fumigata	LDO
PLAF7\|EnsemblGenome=PF3D7_0520600\|UniProtKB=C0H4F3	Plasmodium falciparum	LDO
PHYRM\|Gene=H3GWA2_PHYRM\|UniProtKB=H3GWA2	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_05g247850v5\|UniProtKB=A0A2K3DS22	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_08g385450v5\|UniProtKB=A8IYY6	Chlamydomonas reinhardtii	LDO
NITMS\|EnsemblGenome=Nmar_1417\|UniProtKB=A9A3Q1	Nitrosopumilus maritimus	LDO
PYRAE\|EnsemblGenome=PAE0714\|UniProtKB=Q8ZYM2	Pyrobaculum aerophilum	O
PYRAE\|EnsemblGenome=PAE0252\|UniProtKB=Q7LX33	Pyrobaculum aerophilum	LDO
HALSA\|EnsemblGenome=VNG_0431G\|UniProtKB=Q9HS29	Halobacterium salinarum	LDO
CHLAA\|EnsemblGenome=Caur_2932\|UniProtKB=A9WFX7	Chloroflexus aurantiacus	O
CHLAA\|EnsemblGenome=Caur_1525\|UniProtKB=A9WAW4	Chloroflexus aurantiacus	O
CHLAA\|EnsemblGenome=Caur_3322\|UniProtKB=A9WJ50	Chloroflexus aurantiacus	LDO
STRCO\|Gene_OrderedLocusName=SCO1203\|UniProtKB=Q9FCB0	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv3733c\|UniProtKB=O69700	Mycobacterium tuberculosis	O
STRCO\|Gene_OrderedLocusName=SCO0278\|UniProtKB=Q9S2D5	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO4143\|UniProtKB=Q9KZV8	Streptomyces coelicolor	LDO
STRR6\|EnsemblGenome=spr0721\|UniProtKB=Q8DQE1	Streptococcus pneumoniae	LDO
BACCR\|EnsemblGenome=BC_3037\|UniProtKB=Q81BV5	Bacillus cereus	LDO
CHLTR\|EnsemblGenome=CT_771\|UniProtKB=O84776	Chlamydia trachomatis	LDO
AQUAE\|EnsemblGenome=aq_158\|UniProtKB=O66548	Aquifex aeolicus	LDO
THEYD\|EnsemblGenome=THEYE_A0224\|UniProtKB=B5YI07	Thermodesulfovibrio yellowstonii	LDO
COXBU\|EnsemblGenome=CBU_0598\|UniProtKB=Q83DU4	Coxiella burnetii	LDO
XANCP\|EnsemblGenome=XCC2883\|UniProtKB=Q8P6T2	Xanthomonas campestris	LDO
YERPE\|Gene_OrderedLocusName=YPO2054\|UniProtKB=A0A2S9PHG8	Yersinia pestis	LDO