PANTHER Gene Information

Gene Symbol(s):

jac-1

Organism:

Caenorhabditis elegans

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Gene Name:

Juxtamembrane domain-associated catenin

Gene ID:

WBGene00002175

Protein ID:

Q9U308

Persistent Id:

PTN000042957

Alternate Ids:

Q2HQL5(AltAccession)	CAB60320(EMBL-CDS)
p120 catenin homolog(Synonym)	JAC1_CAEEL(UniProtKB-ID)
Y105C5B.21a(WormBase_TRS)	CE32231(WormBase_PRO)
178451(GeneID)	jac-1(Symbol)
AL110479(EMBL)	WBGene00002175(WormBase)
WBGene00002175(Ensembl)	75025630(GI)
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PANTHER Classification

PANTHER Family:	PLAKOPHILLIN-RELATED (PTHR10372)
PANTHER Subfamily:	ADHERENS JUNCTION PROTEIN P120 (PTHR10372:SF27)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	nucleus plasma membrane adherens junction cytoplasm
PANTHER protein class:	intermediate filament binding protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	protein binding, cadherin binding
GO BP Complete:	regulation of actin cytoskeleton organization, regulation of protein localization, embryonic body morphogenesis, cell adhesion, cell-cell adhesion
GO CC Complete:	nucleus, adherens junction, anchoring junction, cytoplasm, catenin complex, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Apoptosis, Signal Transduction, Innate Immune System, VEGFA-VEGFR2 Pathway, Signaling by VEGF, Developmental Biology, Keratinization, Programmed Cell Death, Apoptotic cleavage of cell adhesion proteins, VEGFR2 mediated vascular permeability, Neutrophil degranulation, Apoptotic execution phase, Signaling by Receptor Tyrosine Kinases, Formation of the cornified envelope, Immune System, Apoptotic cleavage of cellular proteins

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9025\|UniProtKB=Q9Y446	Homo sapiens	O
GORGO\|Ensembl=ENSGGOG00000007129.3\|UniProtKB=G3QW31	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000003525.4\|UniProtKB=F7CA43	Macaca mulatta	O
MOUSE\|MGI=MGI=1891830\|UniProtKB=Q9QY23	Mus musculus	O
RAT\|RGD=1309133\|UniProtKB=A0A8I5YBE4	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000048098.2\|UniProtKB=A0A3Q1MSI5	Bos taurus	O
BOVIN\|Gene=PKP3\|UniProtKB=Q08DQ0	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000027302.4\|UniProtKB=I3LFN8	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000026948.3\|UniProtKB=A0A9L0RJQ0	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000007581.6\|UniProtKB=M3W7Z1	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845029240.1\|UniProtKB=A0A8I3Q2T7	Canis lupus familiaris	O
ORNAN\|Ensembl=ENSOANG00000044491.1\|UniProtKB=A0A6I8N1B2	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010020739.1\|UniProtKB=A0A8V0ZFK0	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000013428.4\|UniProtKB=G1KNU2	Anolis carolinensis	O
XENLA\|Gene=pkp3.L\|UniProtKB=Q6DF93	Xenopus laevis	O
XENLA\|Gene=pkp3.S\|UniProtKB=A0A8J0UZQ6	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-489317\|UniProtKB=F7B720	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000005902.2\|UniProtKB=H2LMZ7	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000023370.1\|UniProtKB=A0A3B3I4R6	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-060512-114\|UniProtKB=F1Q8J9	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-130530-870\|UniProtKB=F1QWE6	Danio rerio	O
HUMAN\|HGNC=9026\|UniProtKB=Q99569	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000012559.6\|UniProtKB=H2QIV2	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000001679.3\|UniProtKB=A0A2I2ZRH7	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000011638.4\|UniProtKB=F6PTU9	Macaca mulatta	O
MOUSE\|MGI=MGI=109281\|UniProtKB=Q68FH0	Mus musculus	O
RAT\|RGD=1307840\|UniProtKB=A0A8I6A880	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000013773.6\|UniProtKB=F1MJ11	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000015878.5\|UniProtKB=F1RPT5	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000014290.4\|UniProtKB=A0A3Q2KTS1	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000015402.6\|UniProtKB=A0A337SDE9	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845026973.1\|UniProtKB=A0A8I3Q1A4	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000004479.4\|UniProtKB=F7A8D5	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000006136.3\|UniProtKB=F7CGZ7	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010010824.1\|UniProtKB=A0A8V0Y1Y0	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000010447.4\|UniProtKB=H9GGF2	Anolis carolinensis	O
XENLA\|Gene=pkp4.S\|UniProtKB=A0A8J1LY11	Xenopus laevis	O
XENLA\|Gene=pkp4.L\|UniProtKB=A0A8J0TXF3	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-489870\|UniProtKB=A0A8J0SYX8	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000001869.2\|UniProtKB=H2L8Z4	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000016767.2\|UniProtKB=A0A3B3HE64	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-120411-14\|UniProtKB=A0A2R8QAD2	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000005927.1\|UniProtKB=W5MFJ7	lepisosteus oculatus	O
HUMAN\|HGNC=9024\|UniProtKB=Q99959	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000004820.5\|UniProtKB=H2Q5P7	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000002106.3\|UniProtKB=G3RQ65	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000000595.4\|UniProtKB=F6Y9B8	Macaca mulatta	O
MOUSE\|MGI=MGI=1914701\|UniProtKB=Q9CQ73	Mus musculus	O
RAT\|RGD=1306533\|UniProtKB=F1M7L9	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000002651.6\|UniProtKB=A0A3Q1M2G3	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000000528.4\|UniProtKB=A0A5G2R2I1	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000013566.4\|UniProtKB=A0A3Q2GT10	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000030734.4\|UniProtKB=M3X980	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845016150.1\|UniProtKB=A0A8I3NZ03	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000012782.4\|UniProtKB=F6S0Z1	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000020593.3\|UniProtKB=A0A6I8N3M8	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010011076.1\|UniProtKB=A0A8V0Y9L5	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000012265.4\|UniProtKB=G1KM54	Anolis carolinensis	O
XENLA\|Gene=pkp2.S\|UniProtKB=A0A8J1MQX6	Xenopus laevis	O
XENLA\|Gene=pkp2.L\|UniProtKB=Q6GR18	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-5825462\|UniProtKB=A4IHT2	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000013540.2\|UniProtKB=H2MEG5	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-041210-167\|UniProtKB=B0BF33	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000015230.1\|UniProtKB=W5NDN5	lepisosteus oculatus	O
HUMAN\|HGNC=2515\|UniProtKB=O60716	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000003668.7\|UniProtKB=A0A2I3TBC2	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000015229.3\|UniProtKB=G3RQD5	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000012366.4\|UniProtKB=F6QHE6	Macaca mulatta	O
MOUSE\|MGI=MGI=105100\|UniProtKB=P30999	Mus musculus	O
RAT\|RGD=1305643\|UniProtKB=A0A0G2JXM1	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000002411.6\|UniProtKB=E1BQ11	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000013174.5\|UniProtKB=A0A5G2QJC4	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000017542.4\|UniProtKB=A0A3Q2KZ20	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000006640.6\|UniProtKB=A0A2I2UZ44	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845019357.1\|UniProtKB=A0A8I3P8H1	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000020116.4\|UniProtKB=A0A5F8HFL3	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000009319.3\|UniProtKB=A0A6I8N092	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010026163.1\|UniProtKB=A0A3Q2U1A5	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000006926.4\|UniProtKB=A0A803T8Q1	Anolis carolinensis	O
XENLA\|Gene=ctnnd1.L\|UniProtKB=A0A8J1L484	Xenopus laevis	O
XENLA\|Gene=ctnnd1\|UniProtKB=Q8AXM9	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-919827\|UniProtKB=F7C4Y1	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000010944.2\|UniProtKB=H2M5J8	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000003733.2\|UniProtKB=A0A3B3IKZ4	Oryzias latipes	O
DANRE\|Gene=ctnnd1\|UniProtKB=A0A8M9Q686	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000007942.1\|UniProtKB=W5MMP6	lepisosteus oculatus	O
HUMAN\|HGNC=728\|UniProtKB=O00192	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000014071.6\|UniProtKB=H2RDK0	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000006706.3\|UniProtKB=G3QV08	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000017153.4\|UniProtKB=F7H0U5	Macaca mulatta	LDO
MOUSE\|MGI=MGI=109620\|UniProtKB=P98203	Mus musculus	LDO
RAT\|RGD=1306655\|UniProtKB=B4F7F3	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000001473.7\|UniProtKB=A0A3Q1LH28	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000010133.5\|UniProtKB=A0A8X9AEP8	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000026951.3\|UniProtKB=A0A9L0TK54	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000002686.6\|UniProtKB=A0A2I2UNP3	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845028288.1\|UniProtKB=A0A8I3Q0V1	Canis lupus familiaris	LDO
ORNAN\|Ensembl=ENSOANG00000038057.1\|UniProtKB=A0A6I8NBV2	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010024616.1\|UniProtKB=A0A8V0ZTI6	Gallus gallus	LDO
XENLA\|Gene=arvcf.S\|UniProtKB=A0A8J1M4M4	Xenopus laevis	O
XENLA\|Gene=arvcf.L\|UniProtKB=A0A8J1LAV0	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-489677\|UniProtKB=A0A6I8QMY9	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000007658.2\|UniProtKB=A0A3B3H6B0	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000015210.2\|UniProtKB=A0A3B3I8I2	Oryzias latipes	LDO
DANRE\|Gene=arvcfa\|UniProtKB=A0A8N7TBY6	Danio rerio	O
DANRE\|Gene=arvcfb\|UniProtKB=A0A8M3ASI2	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000002429.1\|UniProtKB=W5M3A7	lepisosteus oculatus	LDO
HUMAN\|HGNC=9023\|UniProtKB=Q13835	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000001831.5\|UniProtKB=A0A2I3SMB6	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000012651.3\|UniProtKB=G3RPR6	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000013506.4\|UniProtKB=F6ZE38	Macaca mulatta	O
MOUSE\|MGI=MGI=1328359\|UniProtKB=P97350	Mus musculus	O
RAT\|RGD=1307472\|UniProtKB=D3ZY51	Rattus norvegicus	O
BOVIN\|Gene=PKP1\|UniProtKB=Q28161	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000046350.2\|UniProtKB=G3N156	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000030694.3\|UniProtKB=I3LGN8	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000015220.3\|UniProtKB=F7CVH6	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000004610.6\|UniProtKB=M3W2I5	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845018597.1\|UniProtKB=A0A8I3S0K7	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000000329.4\|UniProtKB=F6VDQ3	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000038923.1\|UniProtKB=A0A6I8N272	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010024891.1\|UniProtKB=A0A8V1A511	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000003509.4\|UniProtKB=R4GBL1	Anolis carolinensis	O
XENLA\|Gene=pkp1.S\|UniProtKB=A0A8J0UK32	Xenopus laevis	O
XENLA\|Gene=pkp1.L\|UniProtKB=A0A8J0UEX0	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-949309\|UniProtKB=A0A8J0SDD9	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000006317.2\|UniProtKB=H2LPF1	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000008336.2\|UniProtKB=H2LWI0	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030131-417\|UniProtKB=E7FBR0	Danio rerio	O
DANRE\|Gene=pkp1\|UniProtKB=A0A8M9P5B3	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000009825.1\|UniProtKB=W5MUF2	lepisosteus oculatus	O
HUMAN\|HGNC=2516\|UniProtKB=Q9UQB3	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000016731.6\|UniProtKB=A0A2I3RS45	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000014843.4\|UniProtKB=G3RWI8	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000023419.4\|UniProtKB=F7F975	Macaca mulatta	O
MOUSE\|MGI=MGI=1195966\|UniProtKB=O35927	Mus musculus	O
BOVIN\|Ensembl=ENSBTAG00000017222.7\|UniProtKB=A0A3Q1NJC6	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000016780.5\|UniProtKB=A0A5G2QHN8	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000010901.5\|UniProtKB=A0A3Q2HV94	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000002522.6\|UniProtKB=A0A337SQ12	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845020488.1\|UniProtKB=A0A8I3PDS0	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000002489.4\|UniProtKB=A0A5F8H2T9	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000011600.3\|UniProtKB=A0A6I8PB32	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010000799.1\|UniProtKB=A0A8V0X3V8	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000002855.4\|UniProtKB=A0A803SMA3	Anolis carolinensis	O
XENLA\|Gene=LOC108718510\|UniProtKB=A0A8J1KZE5	Xenopus laevis	O
XENTR\|Gene=ctnnd2\|UniProtKB=A0A8J1JNS2	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000012747.2\|UniProtKB=A0A3B3HSS8	Oryzias latipes	O
DANRE\|Gene=ctnnd2b\|UniProtKB=A0A8M3B7R3	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-030616-60\|UniProtKB=A0A286Y804	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000013495.1\|UniProtKB=W5N7P2	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000009410.3\|UniProtKB=F6TM19	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118427953\|UniProtKB=A0A9J7N5B0	Branchiostoma floridae	LDO
CAEBR\|Gene_ORFName=CBG13693\|UniProtKB=A8XIH7	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00277017\|UniProtKB=A0A2A6BYN3	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0260799\|UniProtKB=Q7PLI0	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP028624\|UniProtKB=A0A1S4HF02	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC001464\|UniProtKB=A0A139WPD3	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_327969\|UniProtKB=E9HCB4	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW015271\|UniProtKB=B7QNP2	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG191187\|UniProtKB=T1FSQ3	helobdella robusta	LDO
TRIAD\|EnsemblGenome=TriadG13097\|UniProtKB=B3S5T4	Trichoplax adhaerens	LDO