PANTHER Gene Information   
Gene Symbol(s): Tdg
Organism: Drosophila melanogaster
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Gene Name: FI14922p
Gene ID: FBgn0026869
Protein ID: Q9V4D8
Persistent Id: PTN000255449
Alternate Ids:
43796(GeneID) 442614406(GI)
FBpp0305856(Ensembl_PRO) FBgn0026869(FlyBase)
Q9V4D8(Synonym) FBtr0333706(Ensembl_TRS)
AEF33880(EMBL-CDS) BT128699(EMBL)
NP_001259060(refSeq) FBgn0026869(Ensembl)
Q9V4D8_DROME(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: G/T AND G/U MISMATCH-SPECIFIC DNA GLYCOSYLASE (PTHR12159)
PANTHER Subfamily: G_T MISMATCH-SPECIFIC THYMINE DNA GLYCOSYLASE (PTHR12159:SF9)  
PANTHER GO-slim Molecular Function: DNA N-glycosylase activity
PANTHER GO-slim Biological Process: base-excision repair
PANTHER GO-slim Cellular Component:
PANTHER protein class: DNA glycosylase
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: DNA binding, uracil DNA N-glycosylase activity, G/U mismatch-specific uracil-DNA glycosylase activity, pyrimidine-specific mismatch base pair DNA N-glycosylase activity, double-stranded DNA binding, mismatch base pair DNA N-glycosylase activity
GO BP Complete: base-excision repair, AP site formation, mismatch repair
GO CC Complete: nucleus
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: DNA Repair, Base Excision Repair, TET1,2,3 and TDG demethylate DNA, Metabolism of proteins, SUMOylation of DNA damage response and repair proteins, Gene expression (Transcription), Post-translational protein modification, Displacement of DNA glycosylase by APEX1, Base-Excision Repair, AP Site Formation, SUMOylation, SUMO E3 ligases SUMOylate target proteins, Cleavage of the damaged pyrimidine , Resolution of Abasic Sites (AP sites), Epigenetic regulation of gene expression, Depyrimidination

Orthologs