PANTHER Gene Information

Gene Symbol(s):

eIF2Balpha

Organism:

Drosophila melanogaster

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Gene Name:

eIF-2B GDP-GTP exchange factor subunit alpha

Gene ID:

FBgn0039726

Protein ID:

Q9VAD4

Persistent Id:

PTN000028102

Alternate Ids:

Q9VAD4_DROME(UniProtKB-ID)	NP_651752(refSeq)
FBgn0039726(Ensembl)	AAF56977(EMBL-CDS)
43549(GeneID)	16768640(GI)
FBpp0084874(Ensembl_PRO)	FBgn0039726(FlyBase)
Q9VAD4(Synonym)	FBtr0085508(Ensembl_TRS)
AJ344146(EMBL)
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PANTHER Classification

PANTHER Family:	TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA (PTHR45860)
PANTHER Subfamily:	TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA (PTHR45860:SF1)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	translation initiation factor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	translation initiation factor activity, guanyl-nucleotide exchange factor activity, enzyme regulator activity
GO BP Complete:	translational initiation
GO CC Complete:	eukaryotic translation initiation factor 2B complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Recycling of eIF2:GDP, Translation, Metabolism of proteins, Eukaryotic Translation Initiation, Cap-dependent Translation Initiation

Orthologs

ID	Organism	Type
HUMAN\|HGNC=3257\|UniProtKB=Q14232	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000005603.6\|UniProtKB=H2Q762	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000009165.3\|UniProtKB=G3R1A1	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000013181.4\|UniProtKB=H9ETU6	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2384802\|UniProtKB=Q99LC8	Mus musculus	LDO
RAT\|RGD=620819\|UniProtKB=Q64270	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000007269\|UniProtKB=Q0IIF2	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000016241.3\|UniProtKB=A0A8W4FH38	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000009770.5\|UniProtKB=A0A286ZJA8	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000021362.4\|UniProtKB=F6R6B2	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000003771.6\|UniProtKB=A0A337RW87	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845017139.1\|UniProtKB=A0A8I3P3X9	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000049098.1\|UniProtKB=A0A5F8GWI8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000015331.4\|UniProtKB=F7CNV5	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010024701.1\|UniProtKB=F1NLG8	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000035138.1\|UniProtKB=A0A803THL1	Anolis carolinensis	LDO
XENLA\|Gene=eif2b1.L\|UniProtKB=Q6NUG3	Xenopus laevis	O
XENLA\|Gene=eif2b1.S\|UniProtKB=A0A8J0U9V9	Xenopus laevis	LDO
XENTR\|Gene=eif2b1\|UniProtKB=A0A8J0SPE0	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000000423.2\|UniProtKB=H2L439	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040625-25\|UniProtKB=A0A0R4ILD9	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000005846.1\|UniProtKB=W5MFC2	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000006234.3\|UniProtKB=F6YCP6	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_114409\|UniProtKB=C3YD85	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC115918810\|UniProtKB=A0A7M7P7M2	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00014221\|UniProtKB=P34604	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00031538\|UniProtKB=A8XAA1	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00103901\|UniProtKB=A0A454XZQ6	Pristionchus pacificus	LDO
ANOGA\|EnsemblGenome=AGAP003650\|UniProtKB=Q7QAK5	Anopheles gambiae	LDO
ANOGA\|EnsemblGenome=AGAP012611\|UniProtKB=Q7QLJ5	Anopheles gambiae	LDO
ANOGA\|EnsemblGenome=AGAP012799\|UniProtKB=A0A1S4HA58	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC004385\|UniProtKB=D6X539	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_216985\|UniProtKB=E9HB01	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW024266\|UniProtKB=B7PJZ1	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g246207\|UniProtKB=A7SMK4	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG20160\|UniProtKB=B3RK01	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_19405\|UniProtKB=A9UQZ5	Monosiga brevicollis	LDO
YEAST\|SGD=S000001734\|UniProtKB=P14741	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AFR084C\|UniProtKB=Q754J0	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000186383\|UniProtKB=A0A1D8PQT4	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_C18161g\|UniProtKB=Q6CBJ8	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_00167\|UniProtKB=Q5BH13	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_5G11340\|UniProtKB=Q4WV99	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU04344\|UniProtKB=Q7RX32	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_08344\|UniProtKB=A7ESN9	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_14011\|UniProtKB=Q0U2M2	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPCC11E10.07c\|UniProtKB=Q9USP0	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_03678\|UniProtKB=B6K4W4	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNC01730\|UniProtKB=Q5KKV3	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_03171\|UniProtKB=A0A0D1E216	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_05021\|UniProtKB=E3K3K8	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_9589\|UniProtKB=F4NW18	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_096380\|UniProtKB=C4LWF1	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0288961\|UniProtKB=Q54I81	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_88551\|UniProtKB=F0ZQ29	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_12_0010\|UniProtKB=Q4QGU3	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb927.6.1280\|UniProtKB=Q585B9	Trypanosoma brucei	LDO
GIAIC\|EnsemblGenome=GL50803_91911\|UniProtKB=A8BJN3	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_118970\|UniProtKB=A2D744	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_0828500\|UniProtKB=Q8IBB6	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00007508001\|UniProtKB=A0CH01	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00015208001\|UniProtKB=A0DB97	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_264824\|UniProtKB=B8CFP0	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GUH8_PHYRM\|UniProtKB=H3GUH8	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_16g687518v5\|UniProtKB=A0A2K3CW67	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00129p00098240\|UniProtKB=W1NJT8	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_81G00940\|UniProtKB=A0A0K9NM89	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma11_g08810\|UniProtKB=A0A804L5T0	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma08_g18640\|UniProtKB=A0A804K846	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_022406mg\|UniProtKB=K3Z786	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3008G101600\|UniProtKB=A0A1Z5R6U1	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb138200\|UniProtKB=B6TJL9	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os12g0497400\|UniProtKB=Q2QQD9	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_4g07040v3\|UniProtKB=I1IIA4	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0499540\|UniProtKB=A0A8I6XIL8	Hordeum vulgare subsp. vulgare	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0456970\|UniProtKB=F2D4N6	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS5B02G113900\|UniProtKB=A0A3B6LGW7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5A02G109200\|UniProtKB=A0A3B6KET8	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS5D02G121400\|UniProtKB=A0A3B6MPH6	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_019126\|UniProtKB=A0A1U8AZK8	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110787206\|UniProtKB=A0A9R0IDX6	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HanXRQr2_Chr04g0138851\|UniProtKB=A0A9K3NQ68	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C400193310\|UniProtKB=A0A9R1XHR6	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C100016360\|UniProtKB=A0A9R1XSH0	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a007694mg\|UniProtKB=A0A022RZF9	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_30654\|UniProtKB=A0A2G2Y971	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400003233\|UniProtKB=M0ZUH2	Solanum tuberosum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400028851\|UniProtKB=M1CTD9	Solanum tuberosum	LDO
TOBAC\|Gene=LOC107780329\|UniProtKB=A0A1S3YWD5	Nicotiana tabacum	O
TOBAC\|Gene=LOC107822215\|UniProtKB=A0A1S4CSY3	Nicotiana tabacum	O
TOBAC\|Gene=LOC107777280\|UniProtKB=A0A1S3YL40	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi09g00027\|UniProtKB=D7TZK5	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_J02599\|UniProtKB=A0A059AH31	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00062323001\|UniProtKB=A0A078HGT8	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00024605001\|UniProtKB=A0A078GFC5	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra039699\|UniProtKB=M4FF27	Brassica campestris	LDO
ARATH\|TAIR=locus=2197046\|UniProtKB=F4HTE0	Arabidopsis thaliana	LDO
ARATH\|TAIR=locus=2814880\|UniProtKB=A0A1P8AT59	Arabidopsis thaliana	LDO
BRACM\|EnsemblGenome=Bra008029\|UniProtKB=M4CUY4	Brassica campestris	O
ARATH\|TAIR=locus=2193932\|UniProtKB=A0A1P8AVS2	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107958346\|UniProtKB=A0A1U8PH01	Gossypium hirsutum	O
GOSHI\|Gene=LOC107906034\|UniProtKB=A0A1U8JDH8	Gossypium hirsutum	O
GOSHI\|Gene=LOC107960281\|UniProtKB=A0A1U8PLM2	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_029241\|UniProtKB=A0A061GCS0	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g016064mg\|UniProtKB=A0A067EIS9	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_003G072100v3\|UniProtKB=B9GXY9	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_001G163300v3\|UniProtKB=B9N7H9	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_11G013200\|UniProtKB=A0A2C9UXB3	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0417980\|UniProtKB=B9T3Y5	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_07G045300\|UniProtKB=I1KHI7	Glycine max	O
MEDTR\|EnsemblGenome=MTR_8g023040\|UniProtKB=G7L962	Medicago truncatula	O
SOYBN\|EnsemblGenome=GLYMA_19G262500\|UniProtKB=A0A0R0F3P0	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_03G263500\|UniProtKB=I1JS74	Glycine max	LDO
JUGRE\|EnsemblGenome=Jr12_16630\|UniProtKB=A0A2I4G5S8	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_7G448030\|UniProtKB=A0A0A0KCC1	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_3G031500\|UniProtKB=A0A251PUI3	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_131440\|UniProtKB=D8T430	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_177636\|UniProtKB=D8S7R3	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c3_36280\|UniProtKB=A0A7I4DEL1	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c5_19430\|UniProtKB=A0A2K1KKA7	Physcomitrella patens	LDO
PHYPA\|EnsemblGenome=Pp3c16_17800\|UniProtKB=A0A7I4B773	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0002s0094\|UniProtKB=A0A2R6XU40	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_003830130\|UniProtKB=A0A1Y1IA72	Klebsormidium nitens	LDO