PANTHER Gene Information   
Gene Symbol(s): puc
Organism: Drosophila melanogaster
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Gene Name: Puckered, isoform A
Gene ID: FBgn0243512
Protein ID: Q9VHV8
Persistent Id: PTN000017188
Alternate Ids:
FBpp0081288(Ensembl_PRO) FBgn0243512(FlyBase)
AAL29164(EMBL-CDS) NM_079549(refSeq)
261824977(GI) AE014297(EMBL)
Q9VHV8(Synonym) Q9VHV8_DROME(UniProtKB-ID)
FBgn0243512(Ensembl) FBtr0081792(Ensembl_TRS)
40958(GeneID)
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PANTHER Classification
PANTHER Family: DUAL SPECIFICITY PROTEIN PHOSPHATASE (PTHR10159)
PANTHER Subfamily: PUCKERED, ISOFORM A (PTHR10159:SF528)  
PANTHER GO-slim Molecular Function: protein tyrosine phosphatase activity
PANTHER GO-slim Biological Process: peptidyl-tyrosine dephosphorylation
negative regulation of MAPK cascade
PANTHER GO-slim Cellular Component: cytosol
PANTHER protein class: protein phosphatase
Pathway Categories: Oxidative stress response
   Mitogen activated protein kinase phosphatase 5
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: phosphoprotein phosphatase activity, protein tyrosine/threonine phosphatase activity, MAP kinase tyrosine phosphatase activity, JUN kinase phosphatase activity, MAP kinase tyrosine/serine/threonine phosphatase activity
GO BP Complete: dorsal closure, negative regulation of MAPK cascade, determination of adult lifespan, chitin-based embryonic cuticle biosynthetic process, epidermis development, JNK cascade, negative regulation of programmed cell death, positive regulation of border follicle cell migration, embryonic anterior midgut (ectodermal) morphogenesis, response to oxidative stress, wound healing, follicle cell of egg chamber development, negative regulation of peptidoglycan recognition protein signaling pathway, negative regulation of stress-activated protein kinase signaling cascade, positive regulation of immune response, imaginal disc fusion, thorax closure, signal transduction, imaginal disc eversion, determination of digestive tract left/right asymmetry, protein dephosphorylation, dorsal appendage formation, protein secretion, imaginal disc fusion, compound eye development, chorion micropyle formation, imaginal disc-derived male genitalia morphogenesis, positive regulation of gene expression, negative regulation of tumor necrosis factor-mediated signaling pathway, negative regulation of apoptotic process, cellular response to oxidative stress, actin cytoskeleton organization, regulation of G2/M transition of mitotic cell cycle
GO CC Complete: cytoplasm, cytosol, endoplasmic reticulum, Golgi apparatus
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: MAPK1/MAPK3 signaling, RAF-independent MAPK1/3 activation, MAPK family signaling cascades, RAF/MAP kinase cascade, Signal Transduction, Negative regulation of MAPK pathway

Orthologs